Challenges
Datasets
Workspaces
Papers
Discussions
Leaderboard
Log inSign up
Challenges
Datasets
Workspaces
Papers
Discussions
Leaderboard
Blog
Job Board
Q3AS

© 2026 Aqora Quantum S.A.S.

TermsPrivacyLegal Notice

Biosystems

Contextuality, incompatibility, and intra-system entanglement of mental markers: From cognition and decision making to medicine

Andrei Yu. Khrennikov, Felix Benninger, Oded Shor, Irina Basieva

Published Jun 24, 2026• 2 citations
Publisher

Abstract

Over the past two decades, quantum-like modeling (QLM) has emerged as a powerful framework for describing non-classical features of cognition and decision-making. Rather than assuming physical quantum processes in the brain, QLM employs the Hilbert space formalism to model contextuality, incompatibility of mental observables, and entanglement-like correlations. In this paper, we develop a quantum-informational model of mental markers within the broader information field approach. We propose that, under conditions of information overload and limited cognitive resources, individuals primarily respond not to detailed semantic content but to compact content labels - mental markers - carrying cognitive and affective components. We formalize mental markers as structured quantum-like states and analyze the nonclassical correlations between their cognitive and affective components using the Contextuality-Incompatibility-Entanglement triad. Special attention is given to intra-system entanglement between rational (cognitive) evaluation and emotional (affective) coloring, accounting for context-dependent judgments, order effects, and affect-driven decision shifts. Illustrative examples with psychological interpretation and experimental perspectives are provided. Appendix B briefly discusses neurobiological analogues of information overload in neural networks, highlighting structural parallels with the proposed marker-based framework; coupling to the origin and diagnostics of neurological diseases is analyzed. The paper contributes to QLM by distinguishing inter-system and intra-system entanglement and by demonstrating that cognitive-affective entanglement constitutes a fundamental structural feature of mental markers in socially mediated information environments.

DOI
10.1016/j.biosystems.2026.105860

Related papers

Contextuality, Incompatibility, and Intra-System Entanglement of Mental Markers

Andrei Yu. Khrennikov, Felix Benninger, Oded Shor

Over the past two decades, quantum-like modeling (QLM) has emerged as a powerful framework for describing non-classical features of cognition and decision-making. Rather than assuming physical quantum processes in the brain, QLM employs the Hilbert space formalism to model contextuality, incompatibility of mental observables, and entanglement-like correlations. In this paper, we develop a quantum-informational model of mental markers within the broader I-field (information field) approach. We propose that, under conditions of information overload and limited cognitive resources, individuals primarily respond not to detailed semantic content but to compact content labels - mental markers - carrying cognitive and affective components. We formalize mental markers as structured quantum-like states and analyze the nonclassical correlations between their cognitive and affective components using the Contextuality-Incompatibility-Entanglement triad. Special attention is given to intra-system entanglement between rational (cognitive) evaluation and emotional (affective) coloring, accounting for context-dependent judgments, order effects, and affect-driven decision shifts. Illustrative examples with psychological interpretation and experimental perspectives are provided. An Appendix briefly discusses neurobiological analogues of information overload in neural networks, highlighting structural parallels with the proposed marker-based framework; coupling to the origin and diagnostics of neurological diseases is analyzed. The paper contributes to QLM by distinguishing inter-system and intra-system entanglement and by demonstrating that cognitive - affective entanglement constitutes a fundamental structural feature of mental markers in socially mediated information environments.

arXiv:2603.03358•Feb 27, 2026•0 citations

Quantum-like representation of neuronal networks' activity: modeling “mental entanglement”

Andrei Yu. Khrennikov, Makiko Yamada

Quantum-like modeling (QLM) – quantum theory applications outside of physics – are intensively developed with applications in biology, cognition, psychology, and decision-making. For cognition, QLM should be distinguished from quantum reductionist models in the spirit of Hameroff and Penrose and well as Umezawa and Vitiello. QLM is not concerned with just quantum physical processes in the brain but also QL information processing by macroscopic neuronal structures. Although QLM of cognition and decision-making has seen some success, it suffers from a knowledge gap that exists between oscillatory neuronal network functioning in the brain and QL behavioral patterns. Recently, steps toward closing this gap have been taken using the generalized probability theory and prequantum classical statistical field theory (PCSFT) – a random field model beyond the complex Hilbert space formalism. PCSFT is used to move from the classical ``oscillatory cognition'' of the neuronal networks to QLM for decision-making. In this study, we addressed the most difficult problem within this construction: QLM for entanglement generation by classical networks, i.e., “mental entanglement.” We started with the observational approach to entanglement based on operator algebras describing “local observables” and bringing into being the tensor product structure in the space of QL states. Moreover, we applied the standard states entanglement approach: entanglement generation by spatially separated networks in the brain. Finally, we discussed possible future experiments on “mental entanglement” detection using the EEG/MEG technique.

arXiv:2509.16253•Frontiers in Human Neuroscience•Dec 9, 2025•11 citations

Quantum-like representation of neuronal networks’ activity: modelling “mental entanglement”

Yamada Makiko, Andrei Yu. Khrennikov

Quantum-like modeling (QLM)– quantum theory applications outside of physics– are intensively developed with applications in biology, cognition, psychology, and decision-making. For cognition, QLM should be distinguished from quantum reductionist models in the spirit of Hameroff and Penrose and well as Umezawa and Vitiello. QLM is not concerned with just quantum physical processes in the brain but also QL information processing by macroscopic neuronal structures. Although QLM of cognition and decision-making has seen some success, it suffers from a knowledge gap that exists between oscillatory neuronal network functioning in the brain and QL behavioral patterns. Recently, steps toward closing this gap have been taken using the generalized probability theory and prequantum classical statistical field theory (PCSFT)– a random field model beyond the complex Hilbert space formalism. PCSFT is used to move from the classical “oscillatory cognition” of the neuronal networks to QLM for decision-making. In this study, we addressed the most difficult problem within this construction: QLM for entanglement generation by classical networks, i.e., “mental entanglement”. We started with the observational approach to entanglement based on operator algebras describing “local observables” and bringing into being the tensor product structure in the space of QL states. Moreover, we applied the standard states entanglement approach: entanglement generation by spatially separated networks in the brain. Finally, we discussed possible future experiments on “mental entanglement” detection using the EEG/MEG technique.

•Oct 1, 2025•0 citations

Quantum-like representation of neuronal networks’ activity: modeling “mental entanglement”

Makiko Yamada, Andrei Yu. Khrennikov

Quantum-like modeling (QLM) – quantum theory applications outside of physics – are intensively developed with applications in biology, cognition, psychology, and decision-making. For cognition, QLM should be distinguished from quantum reductionist models in the spirit of Hameroff and Penrose and well as Umezawa and Vitiello. QLM is not concerned with just quantum physical processes in the brain but also QL information processing by macroscopic neuronal structures. Although QLM of cognition and decision-making has seen some success, it suffers from a knowledge gap that exists between oscillatory neuronal network functioning in the brain and QL behavioral patterns. Recently, steps toward closing this gap have been taken using the generalized probability theory and prequantum classical statistical field theory (PCSFT) – a random field model beyond the complex Hilbert space formalism. PCSFT is used to move from the classical ``oscillatory cognition'' of the neuronal networks to QLM for decision-making. In this study, we addressed the most difficult problem within this construction: QLM for entanglement generation by classical networks, i.e., “mental entanglement.” We started with the observational approach to entanglement based on operator algebras describing “local observables” and bringing into being the tensor product structure in the space of QL states. Moreover, we applied the standard states entanglement approach: entanglement generation by spatially separated networks in the brain. Finally, we discussed possible future experiments on “mental entanglement” detection using the EEG/MEG technique.

•Sep 23, 2025•0 citations

Quantum Information Processing in Human Cognition: Bridging Quantum Phenomena, Neural Dynamics, and Decision‐Making

Hamidreza Namazi, Arvindhan M, Helena Chytilova +1 more

ABSTRACT Recent advances at the intersection of quantum physics, neuroscience, and cognitive science have renewed interest in whether quantum phenomena and quantum‐inspired formalisms can inform models of human cognition and decision‐making. While classical neural and computational models explain many aspects of perception and behavior, they face limitations in accounting for contextuality, order effects, probabilistic reasoning violations, ambiguity resolution, and rapid information integration. This review synthesizes evidence and theoretical frameworks linking quantum‐related principles to cognition, with emphasis on quantum sensing in biological systems, molecular and subcellular quantum‐relevant mechanisms, quantum‐to‐classical transition pathways, quantum‐inspired models of perception and decision‐making, and quantum‐inspired computational approaches. It also extends beyond the probabilistic arm of quantum cognition by considering emerging equilibrium‐based and causal‐logical theories, including mental equilibrium, brain‐universe similarity, mind‐light‐matter unity, quantum emergence, and quantum intelligence. Throughout, the review distinguishes physically instantiated quantum mechanisms from abstract quantum‐like formalisms that model contextuality, mental entanglement, and non‐separable cognitive dynamics without requiring sustained macroscopic quantum coherence in the brain. Finally, it identifies methodological challenges and future directions for advancing quantum cognitive science toward experimentally testable and biologically meaningful theories.

Advanced Quantum Technologies•Jun 1, 2026•1 citation

Coupling quantum-like cognition with the neuronal networks within generalized probability theory

Andrei Yu. Khrennikov, Masanao Ozawa, Felix Benninger +1 more

The past few years have seen a surge in the application of quantum-like (QL) modeling in fields such as cognition, psychology, and decision-making. Despite the success of this approach in explaining various psychological phenomena, there remains a potential dissatisfaction due to its lack of clear connection to neurophysiological processes in the brain. Currently, it remains a phenomenological approach. In this paper, we develop a QL representation of networks of communicating neurons. This representation is not based on standard quantum theory but on generalized probability theory (GPT), with a focus on the operational measurement framework (see section 2.1 for comparison of classical, quantum, and generalized probability theories). Specifically, we use a version of GPT that relies on ordered linear state spaces rather than the traditional complex Hilbert spaces. A network of communicating neurons is modeled as a weighted directed graph, which is encoded by its weight matrix. The state space of these weight matrices is embedded within the GPT framework, incorporating effect-observables and state updates within the theory of measurement instruments — a critical aspect of this model. Under the specific assumption regarding neuronal connectivity, the compound system S = ( S 1 , S 2 ) of neuronal networks is represented using the tensor product. This S 1 ⊗ S 2 representation significantly enhances the computational power of S . The GPT-based approach successfully replicates key QL effects, such as order, non-repeatability, and disjunction effects — phenomena often associated with decision interference. Additionally, this framework enables QL modeling in medical diagnostics for neurological conditions like depression and epilepsy. While the focus of this paper is primarily on cognition and neuronal networks, the proposed formalism and methodology can be directly applied to a broad range of biological and social networks. Furthermore, it supports the claims of superiority made by quantum-inspired computing and can serve as the foundation for developing QL-based AI systems, specifically utilizing the QL representation of oscillator networks. • Quantum-like cognition is coupled to functioning of neuronal networks. • Cognitive effects as the order, response replicability, and conjunction effects and neuronal networks. • Generalized probability theory (operational approach) is explored. • A brief review on the basics of generalized probability theory is presented.

arXiv:2411.00036•Journal of Mathematical Psychology•May 1, 2025•17 citations
Over the past two decades, quantum-like modeling (QLM) has emerged as a powerful framework for describing non-classical features of cognition and decision-making. Rather than assuming physical quantum processes in the brain, QLM employs the Hilbert space formalism to model contextuality, incompatibility of mental observables, and entanglement-like correlations. In this paper, we develop a quantum-informational model of mental markers within the broader information field approach. We propose that, under conditions of information overload and limited cognitive resources, individuals primarily respond not to detailed semantic content but to compact content labels - mental markers - carrying cognitive and affective components. We formalize mental markers as structured quantum-like states and analyze the nonclassical correlations between their cognitive and affective components using the Contextuality-Incompatibility-Entanglement triad. Special attention is given to intra-system entanglement between rational (cognitive) evaluation and emotional (affective) coloring, accounting for context-dependent judgments, order effects, and affect-driven decision shifts. Illustrative examples with psychological interpretation and experimental perspectives are provided. Appendix B briefly discusses neurobiological analogues of information overload in neural networks, highlighting structural parallels with the proposed marker-based framework; coupling to the origin and diagnostics of neurological diseases is analyzed. The paper contributes to QLM by distinguishing inter-system and intra-system entanglement and by demonstrating that cognitive-affective entanglement constitutes a fundamental structural feature of mental markers in socially mediated information environments.
Over the past two decades, quantum-like modeling (QLM) has emerged as a powerful framework for describing non-classical features of cognition and decision-making. Rather than assuming physical quantum processes in the brain, QLM employs the Hilbert space formalism to model contextuality, incompatibility of mental observables, and entanglement-like correlations. In this paper, we develop a quantum-informational model of mental markers within the broader I-field (information field) approach. We propose that, under conditions of information overload and limited cognitive resources, individuals primarily respond not to detailed semantic content but to compact content labels - mental markers - carrying cognitive and affective components. We formalize mental markers as structured quantum-like states and analyze the nonclassical correlations between their cognitive and affective components using the Contextuality-Incompatibility-Entanglement triad. Special attention is given to intra-system entanglement between rational (cognitive) evaluation and emotional (affective) coloring, accounting for context-dependent judgments, order effects, and affect-driven decision shifts. Illustrative examples with psychological interpretation and experimental perspectives are provided. An Appendix briefly discusses neurobiological analogues of information overload in neural networks, highlighting structural parallels with the proposed marker-based framework; coupling to the origin and diagnostics of neurological diseases is analyzed. The paper contributes to QLM by distinguishing inter-system and intra-system entanglement and by demonstrating that cognitive - affective entanglement constitutes a fundamental structural feature of mental markers in socially mediated information environments.
Quantum-like modeling (QLM) – quantum theory applications outside of physics – are intensively developed with applications in biology, cognition, psychology, and decision-making. For cognition, QLM should be distinguished from quantum reductionist models in the spirit of Hameroff and Penrose and well as Umezawa and Vitiello. QLM is not concerned with just quantum physical processes in the brain but also QL information processing by macroscopic neuronal structures. Although QLM of cognition and decision-making has seen some success, it suffers from a knowledge gap that exists between oscillatory neuronal network functioning in the brain and QL behavioral patterns. Recently, steps toward closing this gap have been taken using the generalized probability theory and prequantum classical statistical field theory (PCSFT) – a random field model beyond the complex Hilbert space formalism. PCSFT is used to move from the classical ``oscillatory cognition'' of the neuronal networks to QLM for decision-making. In this study, we addressed the most difficult problem within this construction: QLM for entanglement generation by classical networks, i.e., “mental entanglement.” We started with the observational approach to entanglement based on operator algebras describing “local observables” and bringing into being the tensor product structure in the space of QL states. Moreover, we applied the standard states entanglement approach: entanglement generation by spatially separated networks in the brain. Finally, we discussed possible future experiments on “mental entanglement” detection using the EEG/MEG technique.
Quantum-like modeling (QLM)– quantum theory applications outside of physics– are intensively developed with applications in biology, cognition, psychology, and decision-making. For cognition, QLM should be distinguished from quantum reductionist models in the spirit of Hameroff and Penrose and well as Umezawa and Vitiello. QLM is not concerned with just quantum physical processes in the brain but also QL information processing by macroscopic neuronal structures. Although QLM of cognition and decision-making has seen some success, it suffers from a knowledge gap that exists between oscillatory neuronal network functioning in the brain and QL behavioral patterns. Recently, steps toward closing this gap have been taken using the generalized probability theory and prequantum classical statistical field theory (PCSFT)– a random field model beyond the complex Hilbert space formalism. PCSFT is used to move from the classical “oscillatory cognition” of the neuronal networks to QLM for decision-making. In this study, we addressed the most difficult problem within this construction: QLM for entanglement generation by classical networks, i.e., “mental entanglement”. We started with the observational approach to entanglement based on operator algebras describing “local observables” and bringing into being the tensor product structure in the space of QL states. Moreover, we applied the standard states entanglement approach: entanglement generation by spatially separated networks in the brain. Finally, we discussed possible future experiments on “mental entanglement” detection using the EEG/MEG technique.
Quantum-like modeling (QLM) – quantum theory applications outside of physics – are intensively developed with applications in biology, cognition, psychology, and decision-making. For cognition, QLM should be distinguished from quantum reductionist models in the spirit of Hameroff and Penrose and well as Umezawa and Vitiello. QLM is not concerned with just quantum physical processes in the brain but also QL information processing by macroscopic neuronal structures. Although QLM of cognition and decision-making has seen some success, it suffers from a knowledge gap that exists between oscillatory neuronal network functioning in the brain and QL behavioral patterns. Recently, steps toward closing this gap have been taken using the generalized probability theory and prequantum classical statistical field theory (PCSFT) – a random field model beyond the complex Hilbert space formalism. PCSFT is used to move from the classical ``oscillatory cognition'' of the neuronal networks to QLM for decision-making. In this study, we addressed the most difficult problem within this construction: QLM for entanglement generation by classical networks, i.e., “mental entanglement.” We started with the observational approach to entanglement based on operator algebras describing “local observables” and bringing into being the tensor product structure in the space of QL states. Moreover, we applied the standard states entanglement approach: entanglement generation by spatially separated networks in the brain. Finally, we discussed possible future experiments on “mental entanglement” detection using the EEG/MEG technique.
ABSTRACT Recent advances at the intersection of quantum physics, neuroscience, and cognitive science have renewed interest in whether quantum phenomena and quantum‐inspired formalisms can inform models of human cognition and decision‐making. While classical neural and computational models explain many aspects of perception and behavior, they face limitations in accounting for contextuality, order effects, probabilistic reasoning violations, ambiguity resolution, and rapid information integration. This review synthesizes evidence and theoretical frameworks linking quantum‐related principles to cognition, with emphasis on quantum sensing in biological systems, molecular and subcellular quantum‐relevant mechanisms, quantum‐to‐classical transition pathways, quantum‐inspired models of perception and decision‐making, and quantum‐inspired computational approaches. It also extends beyond the probabilistic arm of quantum cognition by considering emerging equilibrium‐based and causal‐logical theories, including mental equilibrium, brain‐universe similarity, mind‐light‐matter unity, quantum emergence, and quantum intelligence. Throughout, the review distinguishes physically instantiated quantum mechanisms from abstract quantum‐like formalisms that model contextuality, mental entanglement, and non‐separable cognitive dynamics without requiring sustained macroscopic quantum coherence in the brain. Finally, it identifies methodological challenges and future directions for advancing quantum cognitive science toward experimentally testable and biologically meaningful theories.
The past few years have seen a surge in the application of quantum-like (QL) modeling in fields such as cognition, psychology, and decision-making. Despite the success of this approach in explaining various psychological phenomena, there remains a potential dissatisfaction due to its lack of clear connection to neurophysiological processes in the brain. Currently, it remains a phenomenological approach. In this paper, we develop a QL representation of networks of communicating neurons. This representation is not based on standard quantum theory but on generalized probability theory (GPT), with a focus on the operational measurement framework (see section 2.1 for comparison of classical, quantum, and generalized probability theories). Specifically, we use a version of GPT that relies on ordered linear state spaces rather than the traditional complex Hilbert spaces. A network of communicating neurons is modeled as a weighted directed graph, which is encoded by its weight matrix. The state space of these weight matrices is embedded within the GPT framework, incorporating effect-observables and state updates within the theory of measurement instruments — a critical aspect of this model. Under the specific assumption regarding neuronal connectivity, the compound system S = ( S 1 , S 2 ) of neuronal networks is represented using the tensor product. This S 1 ⊗ S 2 representation significantly enhances the computational power of S . The GPT-based approach successfully replicates key QL effects, such as order, non-repeatability, and disjunction effects — phenomena often associated with decision interference. Additionally, this framework enables QL modeling in medical diagnostics for neurological conditions like depression and epilepsy. While the focus of this paper is primarily on cognition and neuronal networks, the proposed formalism and methodology can be directly applied to a broad range of biological and social networks. Furthermore, it supports the claims of superiority made by quantum-inspired computing and can serve as the foundation for developing QL-based AI systems, specifically utilizing the QL representation of oscillator networks. • Quantum-like cognition is coupled to functioning of neuronal networks. • Cognitive effects as the order, response replicability, and conjunction effects and neuronal networks. • Generalized probability theory (operational approach) is explored. • A brief review on the basics of generalized probability theory is presented.