Quantum Machine Learning (QML) merges Quantum Computing (QC) and Artificial Intelligence (AI) to solve problems that are intractable by classical computers. At the same time, domains such as finance, healthcare, manufacturing, and transportation domains are transitioning into Internet of Things (IoT)-enabled cyber physical systems generating streams of heterogeneous data with high dimensionality and volume. This work presents a unified scientometric and qualitative review of QML across these sectors. A PRISMA-based screening is followed by a Keyword Co-occurrence Cluster Analysis (KCCA), a Keyword Burst Analysis (KBA), and a Citation Burst Analysis (CBA) using CiteSpace on a Scopus-derived corpus of literature. An evidence-based Technology Readiness Level (TRL) framework is introduced to assess the technology’s maturity. Our findings indicate that the volume of publications has increased after 2022, with healthcare dominating the volume and manufacturing the impact. Furthermore, a clear trend towards the development of hybrid quantum classical architectures is present across all domains. Security applications such as anomaly detection are the most developed QML entry point to IoT systems. All four domains are at a TRL of 3-4, indicating that QML research is still at the concept-validation stage. Challenges include hardware noise, barren plateaus, absence of standardized benchmarks, and encoding heterogeneous data from IoT devices for training QML applications.
Quantum Machine Learning (QML) merges Quantum Computing (QC) and Artificial Intelligence (AI) to solve problems that are intractable by classical computers. At the same time, domains such as finance, healthcare, manufacturing, and transportation domains are transitioning into Internet of Things (IoT)-enabled cyber physical systems generating streams of heterogeneous data with high dimensionality and volume. This work presents a unified scientometric and qualitative review of QML across these sectors. A PRISMA-based screening is followed by a Keyword Co-occurrence Cluster Analysis (KCCA), a Keyword Burst Analysis (KBA), and a Citation Burst Analysis (CBA) using CiteSpace on a Scopus-derived corpus of literature. An evidence-based Technology Readiness Level (TRL) framework is introduced to assess the technology’s maturity. Our findings indicate that the volume of publications has increased after 2022, with healthcare dominating the volume and manufacturing the impact. Furthermore, a clear trend towards the development of hybrid quantum classical architectures is present across all domains. Security applications such as anomaly detection are the most developed QML entry point to IoT systems. All four domains are at a TRL of 3-4, indicating that QML research is still at the concept-validation stage. Challenges include hardware noise, barren plateaus, absence of standardized benchmarks, and encoding heterogeneous data from IoT devices for training QML applications.
The proliferation of large-scale Internet of Things (IoT) networks introduce significant challenges for real-time anomaly detection, particularly due to the massive volume, high speed, and heterogeneity of IoT-generated data. Traditional and deep learning-based models, while effective to some extent, often face computational bottlenecks that limit their scalability and responsiveness in complex IoT environments. To address these limitations, this paper investigates the application of Quantum Machine Learning (QML) for anomaly detection in IoT systems. By leveraging the parallelism and high-dimensional processing capabilities of quantum computing, QML offers a promising pathway to overcome current computational constraints. We propose a novel anomaly detection framework based on Quantum Generative Adversarial Networks (QGANs) designed to enhance security, reliability, and real-time responsiveness across diverse IoT scenarios, including smart homes, industrial IoT, healthcare monitoring, and critical infrastructure protection. Furthermore, this paper provides a comprehensive analysis of existing anomaly detection challenges, practical IoT applications, and outlines future research directions, including hybrid quantum-classical architectures, resource-efficient quantum algorithms for edge computing, and the integration of QML with emerging technologies to ensure scalable, secure, and robust IoT systems.
Quantum Machine Learning (QML) has emerged as a promising interdisciplinary paradigm that integrates quantum computing and machine learning to address limitations of classical approaches in processing complex high-dimensional heterogeneous and imbalanced medical data. This study presents a systematic literature review of QML applications in healthcare based on 94 primary studies published between 2020 and April 2025. The review follows Kitchenham’s guidelines and the PRISMA framework to ensure rigor transparency and reproducibility. Seven research questions were formulated to examine publication trends sources datasets topics quantum model categories algorithms methods and evaluation metrics. Findings reveal a sharp increase in publication activity after 2023 indicating growing academic interest in healthcare-oriented QML. Medical imaging datasets were most frequently used followed by signal-based and tabular datasets with 86.5% of studies relying on public data. Hybrid classical-quantum approaches including CNN-QSVM Quantum Neural Networks and Variational Quantum Classifiers were dominant because they combine classical feature extraction with quantum-enhanced learning. However most studies were conducted in simulation environments rather than real hardware reflecting NISQ limitations including noise decoherence limited qubits and circuit depth constraints. Many results used small curated or imbalanced datasets raising concerns regarding generalizability reproducibility and clinical validity. Although numerous studies reported high accuracy standardized evaluation protocols external validation and uncertainty assessment remain limited. Overall QML in healthcare remains exploratory with substantial potential but significant barriers. This review highlights progress gaps and future directions emphasizing clinically representative datasets robust benchmarking interpretable noise-resilient models and real-hardware implementation to support trustworthy deployment in healthcare systems worldwide settings today.
Abstract Quantum Machine Learning has emerged as a promising field at the intersection of Quantum Computing and Artificial Intelligence, offering the potential to achieve computational advantages over classical machine learning approaches. While classical ML has matured into a robust ecosystem with broad applications, QML remains nascent, constrained by hardware limitations, yet fueled by rapid theoretical and algorithmic developments. This paper presents a comprehensive comparative review of QML and classical ML, focusing on their foundations, complexity, and applications across domains. We analyze where QML models have shown advantages, where they lag behind, and try to provide possible explanations for these results. By synthesizing evidence across neural networks, kernel methods, generative models, representation learning, and clustering, we highlight patterns that indicate when quantum models tend to outperform or underperform classical baselines. We also review real-world applications of QML across diverse domains such as materials science, energy forecasting, healthcare and bioinformatics, transportation, and finance. Finally, we identify open challenges including state preparation, scalability, and benchmarking standards, and propose a roadmap for the development of QML into a field with demonstrable advantages.
Machine Learning (ML) has been extensively utilized in various scientific and engineering domains. But the inherent constraints and computational complexity that arise in classical machine learning are particularly evident when dealing with large-scale, high-dimensional datasets or when attempting to solve intricate optimisation problems. Quantum systems exhibit unconventional patterns that are typically not effectively generated by traditional systems and can also tackle high dimensional and large size datasets efficiently. Therefore, it is believed that quantum computing systems may outperform traditional computing devices in machine learning tasks. Quantum Machine Learning (QML) has emerged as a rapidly developing field that combines the concepts of quantum mechanics and machine learning to solve complex problems across various disciplines. The domain of quantum machine learning investigates the development and execution of quantum software with the potential to facilitate machine learning at a much superior pace compared to traditional computers. However, the major challenges encountered are hardware limitations, noise, and development of quantum algorithms. The objective of this paper is to provide an insight on the foundational principles, essential algorithms, various associated platforms, potential applications and challenges being faced by QML. As data continues to grow in size and complexity, together with the emergence of nonlinear and high-dimensional real-world situations, the computing benefits offered by QML have the potential to facilitate significant advancements in the fields of healthcare, finance, robotics, logistics, communication, and cyber security. This paper presents the basis for future research work related to development of quantum algorithms in the domain of machine learning.
The Internet of Things (IoT) is a constantly expanding system connecting countless devices for seamless data collection and exchange. This has transformed decision-making with data-driven insights across different domains. However, challenges arise concerning security and computational limitations. To strengthen IoT against cyber threats and optimize resource usage, combining quantum computing (QC) with machine learning (ML) is a promising approach. ML enables computers to learn from data and detect patterns without explicit programming. By leveraging ML algorithms, vast datasets from IoT devices can be analyzed, identifying anomalies and forecasting potential security breaches. Yet, conventional ML algorithms may need help with the complexity and scale of IoT data. QC, based on quantum mechanics, offers unparalleled computational speed and scale. Quantum ML algorithms can quickly analyze IoT datasets, identifying patterns and potential threats. This study examines the ideas behind ML, QC, and their potential collaboration within IoT networks. The research focuses on the possibility of improving the security of IoT networks by integrating QC approaches with ML. It also addresses the challenges and limitations of integrating ML and QC in the context of IoT networks. These obstacles include hardware constraints, algorithm complexities, and the need for specialized knowledge.
Quantum Machine Learning (QML) improves quantum computational advantage by utilizing quantum mechanics to process and analyse information far faster than using classical techniques. One significant obstacle in the field of QML is the need for quantum hardware that is both fault-tolerant and noise resilient to implement and execute QML algorithms successfully. Overcoming the difficulties of QML can result in significant advancements in computational speed and accuracy. QML would enable the successful resolution of complex problems that are currently intractable using classical computing methods. This paper provides a comprehensive analysis of the limitations of classical Machine Learning (ML) and offers an overview of QML, highlighting its significance and foundational principles. We explore cutting-edge QML algorithms that leverage quantum parallelism and entanglement, specifically designed for Internet of Things (IoT) networks, to perform tasks more efficiently. We also discuss the architecture of a QML-based IoT network, focusing on integrating quantum computing capabilities into the vast network of interconnected IoT devices. Additionally, the paper introduces fresh perspectives on QML's potential applications, especially in IoT, and proposes future research directions. We offer insights into the structure of QML, its potential applications, and the architectural considerations for integrating QML into IoT. This paper is primarily targeted at engineering managers and strategic decision-makers seeking actionable guidance on the adoption of QML in industrial IoT contexts.