Given the recent prominence of Noisy Intermediate Scale Quantum (NISQ) devices, hybrid quantum-classical neural networks have recently drawn a lot of excitement as a potential solution to improving learning efficiency. Our current paper describes a Hybrid Quantum-Classical Convolutional Neural Network (HQCNN) which is defined as a pretrained backbone of ResNet-18 and a small quantum-enhanced feature-transformation layer of Qiskit. The convolutional high-dimensional features are reduced to the classical eight-dimensional one, which in turn is encoded into a four-qubit parameterized quantum circuit. The resultant quantum expectation values are combined with the compressed features to come up with a hybridized representation of twelve dimensions, used to classify multi-class dataset. Experimental analysis of CIFAR10 data has shown that the suggested HQCNN achieves a test accuracy of 94.74% and improves class-wise precision, recall, and F1-scores than a number of existing hybrid models while using a significantly smaller number of latent features. More investigation into the quantum module indicates that it is predictable about scalability to batch, resistant to perturbations in features, and efficiently performed by evaluating circuit vectors. These results indicate that compact and expressive representations of images that can be helpful in the NISQ era can be acquired using hybrid architectures, thus providing a practical way to forward the benefits of quantum to modern deep-learning pipelines.
Given the recent prominence of Noisy Intermediate Scale Quantum (NISQ) devices, hybrid quantum-classical neural networks have recently drawn a lot of excitement as a potential solution to improving learning efficiency. Our current paper describes a Hybrid Quantum-Classical Convolutional Neural Network (HQCNN) which is defined as a pretrained backbone of ResNet-18 and a small quantum-enhanced feature-transformation layer of Qiskit. The convolutional high-dimensional features are reduced to the classical eight-dimensional one, which in turn is encoded into a four-qubit parameterized quantum circuit. The resultant quantum expectation values are combined with the compressed features to come up with a hybridized representation of twelve dimensions, used to classify multi-class dataset. Experimental analysis of CIFAR10 data has shown that the suggested HQCNN achieves a test accuracy of 94.74% and improves class-wise precision, recall, and F1-scores than a number of existing hybrid models while using a significantly smaller number of latent features. More investigation into the quantum module indicates that it is predictable about scalability to batch, resistant to perturbations in features, and efficiently performed by evaluating circuit vectors. These results indicate that compact and expressive representations of images that can be helpful in the NISQ era can be acquired using hybrid architectures, thus providing a practical way to forward the benefits of quantum to modern deep-learning pipelines.
Image classification is an important application for deep learning. With the advent of quantum technology, quantum neural networks (QNNs) have become the focus of research. Traditional deep learning-based image classification involves using a convolutional neural network (CNN) to extract features from the image and a multi-layer perceptron (MLP) network to create the decision boundaries. However, quantum circuits with parameters can extract rich features from images and also create complex decision boundaries. This paper proposes a hybrid QNN (H-QNN) model designed for binary image classification that capitalizes on the strengths of quantum computing and classical neural networks. Our H-QNN model uses a compact, two-qubit quantum circuit integrated with a classical convolutional architecture, making it highly efficient for computation on noisy intermediate-scale quantum (NISQ) devices that are currently leading the way in practical quantum computing applications. Our H-QNN model significantly enhances classification accuracy, achieving a 90.1% accuracy rate on binary image datasets. In addition, we have extensively evaluated baseline CNN and our proposed H-QNN models for image retrieval tasks. The obtained quantitative results exhibit the generalization of our H-QNN for downstream image retrieval tasks. Furthermore, our model addresses the issue of overfitting for small datasets, making it a valuable tool for practical applications.
Deep learning techniques have significantly enhanced medical image classification for disease diagnosis. However, traditional deep learning models face several challenges, such as dependence on large annotated datasets, complex architectural layers, and millions of trainable parameters, which can increase computational load and cause overfitting. Although quantum computing offers potential for parallel processing and improved feature representation, its practical use is limited by the current capabilities of Noisy Intermediate-Scale Quantum (NISQ) hardware. To overcome these issues, Hybrid Quantum–Classical Convolutional Neural Networks (HQCNNs) have been developed, using quantum properties like superposition and entanglement to improve feature extraction and classification of medical images. This review offers a thorough analysis of 50 peer-reviewed studies published from 2021 to 2026 and introduces a taxonomy of HQCNN architectures. It classifies existing approaches into three categories: Quantum-to-Classical, Classical-to-Quantum, and Hybrid Quantum Transfer Learning. The studies reviewed encompass a diverse range of medical imaging applications, including binary and multi-class disease classification using X-ray, CT, MRI, ultrasound, dermoscopic, retinal, and mammographic images. Additionally, the review compares HQCNNs with their classical CNN counterparts, exploring how factors like quantum circuit design, dataset size, class imbalance, task complexity, evaluation protocols, and hardware limitations influence classification performance. It concludes with an analysis of the key limitations of current HQCNN models, discusses challenges in deploying NISQ devices practically, and proposes future research directions to bridge the gap between experimental HQCNN frameworks and reliable clinical diagnostic systems.
The objective of this research is to develop a Hybrid Quantum-Classical Convolutional Neural Network (QC-CNN) framework that integrates parameterized quantum circuits (PQCs) within classical CNN architectures to enhance image classification performance.The proposed model leverages quantum principles such as superposition and entanglement for high-dimensional feature representation, achieving superior accuracy and reduced computational complexity.Experiments on MNIST and CIFAR-10 datasets demonstrated improved classification accuracy of 98.7% and 82.5%, respectively, surpassing traditional CNNs while reducing training time by 33% and parameters by 45%.Statistical analysis confirmed the significance of these improvements.Visualizations using t-SNE revealed enhanced class separability, and noise perturbation tests validated the model's robustness.The results highlight the hybrid QC-CNN's potential for efficient and scalable quantum-enhanced deep learning applications.Extended evaluations, including quantum-layer-depth analysis, robustness testing, and t-SNE visualization, empirically support the hybrid QC-CNN's effectiveness across varied scenarios.
Medical image classification is a critical component of modern healthcare; however, accurate diagnosis remains challenging due to limited annotated datasets, class imbalance, and the high dimensionality of medical imaging data. To address these challenges, a hybrid quantum-classical neural network (HQCNN) is proposed, integrating classical deep learning with variational quantum learning for medical image classification. The proposed architecture combines a five-layer convolutional neural network (CNN) for hierarchical feature extraction with a lightweight 4-qubit variational quantum circuit (VQC) incorporating quantum state encoding, superposition and entanglement mechanisms, and a quantum attention-Fourier (QAF) module. This hybrid design aims to improve nonlinear feature representation and quantum parameter efficiency while maintaining a shallow quantum circuit suitable for noisy intermediate-scale quantum (NISQ)-era constraints. Experimental evaluation on six MedMNIST benchmark datasets demonstrated competitive performance across both binary and multi-class classification tasks. HQCNN achieved 98.88% accuracy on the binary subset of PathMNIST (classes 0 vs. 1), 97.61% accuracy on the multi-class OrganAMNIST dataset, and 86.29% accuracy on BreastMNIST. Comparative experiments and statistical analyses demonstrated consistent improvements over the controlled BHQNN baseline, while component-wise ablation studies showed that the QAF module, superposition and entanglement mechanisms, and expressive parameterized rotations contributed to classification performance in a complementary and dataset-dependent manner. Moreover, HQCNN reduced the number of trainable quantum parameters by approximately 55.6% compared with the baseline hybrid quantum neural network (BHQNN). Noise-aware simulations further showed that the model retained relatively stable predictive performance under moderate depolarizing noise, supporting further evaluation under near-term quantum computing conditions. Overall, the results demonstrate that HQCNN provides a parameter-efficient hybrid quantum-classical framework for medical image classification and offers a promising foundation for further investigation of quantum-enhanced medical image analysis.
The integration of quantum computing principles with classical deep learning architectures has emerged as a promising direction for advancing image recognition systems beyond the limitations of purely classical convolutional neural networks (CNNs). This study proposes and analyzes a hybrid quantum–classical deep learning framework based on quanvolutional neural network (QNN) principles, where quantum circuits are embedded within convolutional feature extraction layers to enhance representation capability. The research investigates how quantum-enhanced filters, particularly quanvolutional layers, contribute to improved feature diversity, non-linear transformation capacity, and classification accuracy in image recognition tasks. Building upon established convolutional architectures and quantum machine learning theories, the proposed framework integrates quantum random circuit encoding with classical deep neural networks to evaluate performance gains in comparison to conventional CNN models. The study further incorporates theoretical insights from hybrid quantum-classical learning systems, emphasizing the role of parameterized quantum circuits in feature mapping and optimization stability. The methodology is grounded in NISQ-era quantum computing constraints and leverages hybrid optimization strategies to ensure computational feasibility. Experimental evaluation demonstrates that quanvolution-based models can provide improved robustness in feature extraction, particularly in high-dimensional image spaces, while maintaining competitive computational efficiency. However, scalability limitations and noise sensitivity in quantum circuits remain key challenges. Overall, this work contributes to the growing field of quantum-enhanced machine learning by providing a structured performance analysis of hybrid quanvolutional architectures and highlighting their potential role in next-generation intelligent visual recognition systems.
Abstract Quantum Neural Networks (QNNs) present a promising research direction in image recognition, demonstrating significant potential for various applications. However, QNNs with a fixed circuit topology structure are prone to encountering the barren plateaus during training when processing exponential number of qubits, which limit their performance and scalability. In this paper, a novel Hybrid Quantum-Classical Inception-inspired Convolutional Neural Networks (HQCNN) is proposed. The HQCNN enhances feature learning capability and mitigates the barren plateau issue by integrating quantum convolutional kernels with diverse circuit topologies across multiple channels. The architecture employs an amplitude encoding layer to map multi-channel classical data into quantum states, followed by diverse quantum convolutional kernels that extract feature representations. Furthermore, Hadamard gates are used to intergrate multi-channel features and incorporate quantum pooling to reduce feature dimensionality, with a fully connected layer mapping the quantum-enhancing features into class labels for classification tasks. Finally, by analyzing the influence of the circuit structures and quantum gate combinations on the models' performance, the optimal HQCNN architecture is constructed. Experimental results demonstrate that HQCNN achieves 98.5% accuracy on the MNIST-4 classification task and 92.5% accuracy on the MNIST-10 classification task, which indicates that the proposed model outperforms state-of-the-art HQCNN models and classical CNN in image classification with about 10% parameters. This study provides an effective approach for alleviating the barren plateau issue and designing multi-channel quantum convolutional neural networks for processing big classic data with fewer quantum resources.