Variational Quantum Classifiers (VQCs) are a common class of hybrid quantum-classical models developed for nearterm quantum machine learning applications. Despite growing focus, it is still unclear how circuit design choices, particularly entanglement depth, affect learning performance and optimisation stability when compared to reliable classical baselines [1]. In this research, we provide a controlled empirical analysis of entanglement depth in VQCs for medical image classification utilizing pre-extracted deep feature representations. Under a predetermined experimental design, we assessed VQCs with no entanglement, single-layer entanglement, and two-layer interleaved entanglement with different training set sizes. Our findings demonstrate that in low-data regimes, increasing entanglement could negatively impact accuracy due to optimization instability [2] and may not always enhance performance. Since classical machine learning baselines consistently match or surpass quantum models, there is no performance advantage of variational quantum classifiers was observed under the evaluated experimental conditions and preprocessing constraints. These results emphasize the significance of thorough, comparative benchmarking for real-world use and draw attention to the expressivity optimization trade-offs inherent in variational quantum learning.
Variational Quantum Classifiers (VQCs) are a common class of hybrid quantum-classical models developed for nearterm quantum machine learning applications. Despite growing focus, it is still unclear how circuit design choices, particularly entanglement depth, affect learning performance and optimisation stability when compared to reliable classical baselines [1]. In this research, we provide a controlled empirical analysis of entanglement depth in VQCs for medical image classification utilizing pre-extracted deep feature representations. Under a predetermined experimental design, we assessed VQCs with no entanglement, single-layer entanglement, and two-layer interleaved entanglement with different training set sizes. Our findings demonstrate that in low-data regimes, increasing entanglement could negatively impact accuracy due to optimization instability [2] and may not always enhance performance. Since classical machine learning baselines consistently match or surpass quantum models, there is no performance advantage of variational quantum classifiers was observed under the evaluated experimental conditions and preprocessing constraints. These results emphasize the significance of thorough, comparative benchmarking for real-world use and draw attention to the expressivity optimization trade-offs inherent in variational quantum learning.
This study presents a comparative empirical evaluation of Variational Quantum Classifier (VQC) performance within the Quantum Machine Learning (QML) framework, focusing on VQC architectural analysis under NISQ-era qubit constraints. The VQC was designed utilizing ZFeatureMap for data encoding and EfficientSU2 as the ansatz. A systematic test was performed to evaluate the impact of three entanglement topologies (default, circular, pairwise) and two qubit scales (4 and 8) with four classical optimizers on standard classification datasets: Iris, Wine, and Breast Cancer. The results demonstrated that no single configuration is universally optimal. The default topology achieved the highest peak accuracy on multi-class datasets (Iris: 97% with P-BFGS), suggesting its efficiency in simpler parameter landscapes. Conversely, the pairwise and circular topologies showed superior stability and competitive accuracy (up to 92%) on the high-dimensional Breast Cancer dataset, confirming that richer qubit connectivity is essential for effective feature separation in more complex classification problems. Increasing the scale from 4 to 8 qubits was found to be crucial for improving the overall stability and consistency of performance rather than merely increasing peak accuracy. These findings provide essential empirical guidance for designing optimal and trainable VQC architectures under current quantum device limitations.
Quantum machine learning applies principles such as superposition and entanglement to data processing and optimization. Variational quantum models operate on qubits in high-dimensional Hilbert spaces and provide an alternative approach to model expressivity. We compare classical models and a variational quantum classifier on the XOR problem. Logistic regression, a one-hidden-layer multilayer perceptron, and a two-qubit variational quantum classifier with circuit depths 1 and 2 are evaluated on synthetic XOR datasets with varying Gaussian noise and sample sizes using accuracy and binary cross-entropy.
Performance is determined primarily by model expressivity. Logistic regression and the depth-1 quantum circuit fail to represent XOR reliably, whereas the multilayer perceptron and the depth-2 quantum circuit achieve perfect test accuracy under representative conditions. Robustness analyses across noise levels, dataset sizes, and random seeds confirm that circuit depth is decisive for quantum performance on this task. Despite matching accuracy, the multilayer perceptron achieves lower binary cross-entropy and substantially shorter training time. Hardware execution preserves the global XOR structure but introduces structured deviations in the decision function. Overall, deeper variational quantum classifiers can match classical neural networks in accuracy on low-dimensional XOR benchmarks, but no clear empirical advantage in robustness or efficiency is observed in the examined settings.
This study presents a noise-aware evaluation framework for hybrid quantum–classical machine learning models applied to medical binary classification. Using three healthcare datasets—Pima Indians Diabetes, Heart Disease, and Breast Cancer Wisconsin—the performance of a Variational Quantum Classifier (VQC) was analyzed under multiple depolarizing noise levels (0.00–0.10). Classical baselines, Logistic Regression (LR) and Support Vector Machine (SVM), were implemented for comparison. The research investigates the impact of noise on predictive accuracy, F1-score, and training time, highlighting the computational overhead of hybrid quantum–classical models. Zero Noise Extrapolation (ZNE), using linear and Richardson methods, was applied to mitigate noise effects, revealing that while ZNE improves performance under certain conditions, extrapolation instability can occur. Transpiler optimization also contributed to improved VQC stability by reducing circuit complexity. Results show that classical models consistently outperformed the VQC in accuracy, stability, and training efficiency. VQC exhibited fluctuating performance under noise, requiring significantly higher training time, and increasing SPSA iterations did not always yield stable accuracy improvements. These findings underscore the challenges of noise robustness, optimization instability, and computational cost in the NISQ era, and suggest directions for future work, including alternative optimizers, adaptive ansatz design, advanced error mitigation, and real hardware benchmarking. This research provides a systematic benchmarking framework for evaluating training time versus noise-level trade-offs, contributing to the development of more reliable quantum machine learning models for medical applications. Keywords: Quantum Machine Learning, Variational Quantum Classifier, Depolarizing Noise, Zero Noise Extrapolation, Medical Classification, Hybrid Quantum–Classical Models, Training Time Analysis
The practical value of quantum machine learning must be derived from efficiency rather than scale, as current NISQ processors support only small, shallow circuits. This paper evaluated whether variational quantum circuits (VQCs) can reduce the trainable parameter count in an image classification scenario while preserving accuracy. Experimentation compared quantum classifier heads to parameter-matched classical heads on an identical set of frozen features drawn from the Fashion-MNIST dataset by a CNN. 9 configurations of a quantum circuit crossed 4, 6, and 8 qubits with 1, 2, and 4 entangling layers, each matched to a multilayer perceptron with an approximately equal parameter count. The linear probes served as a floor baseline for all 105 runs across 5 random seed values. 7 out of 9 quantum-based configurations met the mean test accuracy of no more than 1 percentage point below its matched classical head, enforced by the pre-specified criterion. The 2 failures were single-layer circuits, with each falling roughly 8 points below its matched classical head and 12 points below the circuit-free linear probe; in total, 6 configs with 2+ layers passed, with the smallest at 74 trainable parameters. The general trend noticed was that accuracy increased progressively with depth. The 4-layer circuits exceeded the linear probe at every qubit count and produced the highest accuracy at 6 and 8 qubits. The simulation ran noiselessly; VQCs preserved accuracy at the matched parameter budget when depth was given, showcasing depth rather than qubit count gating performance.
The increasingly complex cybersecurity landscape requires more advanced network anomaly detection systems. Although, classical machine learning models are known to be effective, they reach computational bottlenecks when processing high-dimensional data. This study investigates the potential of Quantum Machine Learning (QML) for network traffic anomaly detection by evaluating four distinct Variational Quantum Classifier (VQC) architectures. A synthetic network traffic dataset is generated for the evaluations. The VQC models systematically varied feature encoding methods, parameterized ansatz circuits, quantum neural network types, and classical optimizers. Experimental results show that a trade-off exists between circuit expressivity and optimization stability. Deeper circuits (VQC-4) achieved higher accuracy of upto 89.0\%, while simultaneously being sensitive to training conditions. A shallower variant (VQC-1) under performed, although it had consistent and stable optimization curves. Class-dependent biases were also observed such as in VQC-2, where the model struggled to find an effective decision boundary, and produced a large number of false negatives. The best performing model in this study (VQC-3) combined ZFeatureMap with RealAmplitudes ansatz, optimized using ADAM. Comparative analysis against classical machine learning models such as Support Vector Machine and Random Forest reveal a performance gap, where classical models are able to achieve perfect classification performance on the synthetic data. It is concluded that classical algorithms remain dominant in their ability to classify structured data with relatively simple class separations. However, due to the observed potential of certain VQC configurations to learn decision boundaries to classify data, their utility for future applications in noisier, higher-dimensional problems is highlighted.
With the advancement of quantum computing in the Noisy Intermediate-Scale Quantum (NISQ) era, hybrid quantum-classical algorithms have emerged as promising approaches for addressing certain machine learning tasks. This study investigates the Variational Quantum Classifier (VQC), a hybrid model that integrates parameterized quantum circuits with classical optimization routines, implemented via IBM’s Qiskit framework. We provide a detailed account of the VQC architecture, including feature encoding, ansatz construction, and optimization methodology. To assess its performance, we conduct a comparative analysis between VQC and classical Support Vector Classifiers (SVC) across synthetic and real-world datasets, including Iris and a binary-filtered version of MNIST. Experimental results reveal that classical models consistently achieve higher accuracy and faster training times. However, the VQC demonstrates functional viability, particularly under noise-free conditions and reduced-dimensionality settings. These findings underscore the current limitations of quantum models while highlighting the potential of VQC as a proof-of-concept for quantum-enhanced learning as quantum hardware matures.