Quantum computing devices are recognized as powerful tools for solving NP-complete problems. How-ever, the intricacy of their modeling presents notable barriers for non-specialists, while the tedious iteration of constraint weights and modeling methodologies also consumes substantial effort on the part of experts. To address these challenges, this study integrates a femtosecond laser-pumped Coherent Ising Machine (CIM) with an LLM-driven agentic system by leveraging the LangGraph and LangChain frameworks. Com-prehensive investigations demonstrate that large language models (LLMs) can effectively perform such tasks in modeling as QUBO/Ising model calibration, constraint weight decision iteration and rapid validation of literature-reported schemes. Notably, all these tasks can be fully implemented based on domestic large models, combined with domestically developed CIM hardware, we truly achieve the practical empowerment of quantum CIM that fully relies on all-domestic agentic large models and hardware. This work successfully realizes robust technological integration, laying a solid foundation for subsequent research. Nevertheless, it also identifies the persisting challenges in the two cutting-edge fields of large models and quantum computing at the current stage. Encouragingly, we unexpectedly discover a promising new paradigm where accumulated knowledge from agent-assisted quantum computing iterations reciprocally enhances the agent’s own problem-solving capability, thereby addressing these challenges.
Quantum computing devices are recognized as powerful tools for solving NP-complete problems. How-ever, the intricacy of their modeling presents notable barriers for non-specialists, while the tedious iteration of constraint weights and modeling methodologies also consumes substantial effort on the part of experts. To address these challenges, this study integrates a femtosecond laser-pumped Coherent Ising Machine (CIM) with an LLM-driven agentic system by leveraging the LangGraph and LangChain frameworks. Com-prehensive investigations demonstrate that large language models (LLMs) can effectively perform such tasks in modeling as QUBO/Ising model calibration, constraint weight decision iteration and rapid validation of literature-reported schemes. Notably, all these tasks can be fully implemented based on domestic large models, combined with domestically developed CIM hardware, we truly achieve the practical empowerment of quantum CIM that fully relies on all-domestic agentic large models and hardware. This work successfully realizes robust technological integration, laying a solid foundation for subsequent research. Nevertheless, it also identifies the persisting challenges in the two cutting-edge fields of large models and quantum computing at the current stage. Encouragingly, we unexpectedly discover a promising new paradigm where accumulated knowledge from agent-assisted quantum computing iterations reciprocally enhances the agent’s own problem-solving capability, thereby addressing these challenges.
Quantum computing devices are recognized as powerful tools for solving NP-complete problems. However, the intricacy of their modeling presents notable barriers for non-specialists, while the tedious iteration of constraint weights and modeling methodologies also consumes substantial effort on the part of experts. To address these challenges, this study integrates a femtosecond laser-pumped Coherent Ising Machine (CIM) with an LLM-driven agentic system by leveraging the LangGraph and LangChain frameworks. Comprehensive investigations demonstrate that large language models (LLMs) can effectively perform such tasks in modeling as QUBO/Ising model calibration, constraint weight decision iteration and rapid validation of literature-reported schemes. Notably, all these tasks can be fully implemented based on domestic large models, combined with domestically developed CIM hardware, we truly achieve the practical empowerment of quantum CIM that fully relies on all-domestic agentic large models and hardware. This work successfully realizes robust technological integration, laying a solid foundation for subsequent research. Nevertheless, it also identifies the persisting challenges in the two cutting-edge fields of large models and quantum computing at the current stage. Encouragingly, we unexpectedly discover a promising new paradigm where accumulated knowledge from agent-assisted quantum computing iterations reciprocally enhances the agent's own problem-solving capability, thereby addressing these challenges.
Coherent Ising machines (CIMs) have emerged as a hybrid form of quantum computing devices designed to solve NP-complete problems, offering an exciting opportunity for discovering optimal solutions. Despite challenges such as susceptibility to noise-induced local minima, we achieved notable advantages in improving the computational accuracy and stability of CIMs. We conducted a successful experimental demonstration of CIM via femtosecond laser pumping that integrates optimization strategies across optical and structural dimensions, resulting in significant performance enhancements. The results are particularly promising. An average success rate of 55% was achieved to identify optimal solutions within a Möbius Ladder graph comprising 100 vertices. Compared with other alternatives, the femtosecond pulse results in significantly higher peak power, leading to more pronounced quantum effects and lower pump power in optical fiber-based CIMs. In addition, we have maintained an impressive success rate for a continuous period of 8 hours, emphasizing the practical applicability of CIMs in real-world scenarios. Furthermore, our research extends to the application of these principles in practical applications such as molecular docking and credit scoring. The results presented substantiate the theoretical promise of CIMs, paving the way for their integration into large-scale practical applications.
Coherent Ising Machines (CIMs) have emerged as a hybrid form of quantum computing devices designed to solve NP-complete problems, offering an exciting opportunity for discovering optimal solutions. Despite challenges such as susceptibility to noise-induced local minima, we achieved notable advantages in improving the computational accuracy and stability of CIMs. We conducted a successful experimental demonstration of CIM via femto-second laser pumping that integrates optimization strategies across optical and structural dimensions, resulting in significant performance enhancements. The results are particularly promising. An average success rate of 55% was achieved to identify optimal solutions within a Mobius Ladder graph comprising 100 vertices. Compared with other alternatives, the femto-second pulse results in significantly higher peak power, leading to more pronounced quantum effects and lower pump power in optical fiber based CIMs. In addition, we have maintained an impressive success rate for a continuous period of 8 hours, emphasizing the practical applicability of CIMs in real-world scenarios. Furthermore, our research extends to the application of these principles in practical applications such as molecular docking and credit scoring. The results presented substantiate the theoretical promise of CIMs, paving the way for their integration into large-scale practical applications.
The convergence of quantum computing and large language models (LLMs) represents a major milestone in computational intelligence, introducing novel paradigms for information processing, complexity modeling, and scientific advancement. This survey provides a comprehensive overview of the emerging interdisciplinary field that integrates quantum mechanics with natural language processing. We begin by presenting the foundational principles of quantum computing and LLMs, then examine their integration through automated quantum code generation, hybrid transformer architectures, and quantum natural language processing (QNLP) frameworks. State-of-the-art models, such as quantum-augmented attention mechanisms and circuit embedding strategies, are evaluated across domain-specific datasets and benchmarks. We also investigate the role of LLMs as quantum research assistants, educational tools, and simulation agents, particularly in resource-constrained environments. Furthermore, the survey explores challenges related to scalability, interpretability, and quantum data encoding, and outlines future research directions-especially the vision for fully quantum-native LLMs. Our goal is to guide researchers through the current landscape and to encourage continued exploration at the intersection of quantum technologies and advanced language models.
The design of high performing quantum circuits remains largely dependent on human expertise. We introduce an autonomous agentic framework that employs large language models (LLMs) to conduct iterative quantum circuit designs under explicit design constraints. Our system integrates seven components: Exploration, Generation, Discussion, Validation, Storage, Evaluation, and Review. These components form a closed-loop workflow that combines web-based knowledge acquisition, literature-grounded critique, executable code generation, and experimental feedback. We evaluate the framework on two tasks: quantum feature map construction for quantum machine learning and ansatz generation for variational quantum eigensolver applications in quantum chemistry. In image classification benchmarks, the best generated feature map outperforms representative quantum feature maps and, when scaled to larger qubit counts, surpasses the classical radial basis function kernel. In molecular ground state estimation across seven molecules, the generated ansatz attains competitive accuracy with widely used chemically inspired and hardware-efficient constructions while satisfying the imposed scaling constraints. These results establish LLM driven agentic system as a viable paradigm for automated quantum circuit design and illustrate how AI systems can participate in iterative scientific optimization workflows across scientific domains.
Quantum optimal control (QOC) underpins adiabatic quantum computation, quantum annealing, and quantum state engineering, yet practical deployment is fundamentally bottlenecked by strict hardware constraints and substantial expert effort required to design protocols for each problem instance. To overcome this, we introduce QOC-Workbench, an auditable, large language model (LLM)-driven workflow that acts as an automated quantum co-scientist for cross-paradigm protocol design. Going beyond traditional numerical optimizers that merely tune parameters within a fixed formula, the LLM autonomously parses physics literature, proposes structural hypotheses, and writes code to validate them by direct simulation. This workflow supports cross-paradigm design by accumulating control motifs across tasks. We demonstrate this approach across three distinct settings: Case 1, Rydberg-atom maximum-independent-set arrays; Case 2, interacting XXZ spin chains; and Case 3, random transverse-field Ising models. In Cases 1 and 2, the workflow autonomously discovers hardware-compliant auxiliary controls, target catalysts, and schedule deformations that outperform literature baselines. In Case 3, it addresses the computational bottleneck of variational counterdiabatic driving by escalating from per-instance optimization to an amortized graph-neural-network generator, successfully transferring learned coefficient paths to larger unseen systems. By actively bridging the gap between theoretical algorithms and experimental restrictions across distinct control paradigms and Hamiltonian families, QOC-Workbench establishes a continuously evolving, cross-paradigm methodology for autonomous quantum control.