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IEEE Transactions on Quantum Engineering

Extension of Clifford Data Regression Methods for Quantum Error Mitigation

Jordi Pérez-Guijarro, Alba Pagés-Zamora, J.R. Fonollosa

Published Jan 1, 2026• 0 citations
Publisher

Abstract

To address the challenge posed by noise in real quantum devices, quantum error mitigation techniques play a crucial role. These techniques are resource-efficient, making them suitable for implementation in noisy intermediate-scale quantum devices, unlike the more resource-intensive quantum error correction codes. A notable example of such a technique is Clifford Data Regression, which employs a supervised learning approach. This work investigates two variants of this technique, both of which introduce a non-trivial set of gates into the original circuit. The first variant uses multiple copies of the original circuit, while the second adds a layer of single-qubit rotations. Different characteristics of these methods are analyzed theoretically, such as their complexity, or the scaling of the error with various parameters. Additionally, the performance of these methods is evaluated through numerical experiments, demonstrating a reduction in root mean square error.

DOI
10.1109/tqe.2026.3677541

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To address the challenge posed by noise in real quantum devices, quantum error mitigation techniques play a crucial role. These techniques are resource-efficient, making them suitable for implementation in noisy intermediate-scale quantum devices, unlike the more resource-intensive quantum error correction codes. A notable example of such a technique is Clifford Data Regression, which employs a supervised learning approach. This work investigates two variants of this technique, both of which introduce a non-trivial set of gates into the original circuit. The first variant uses multiple copies of the original circuit, while the second adds a layer of single-qubit rotations. Different characteristics of these methods are analyzed theoretically, such as their complexity, or the scaling of the error with various parameters. Additionally, the performance of these methods is evaluated through numerical experiments, demonstrating a reduction in root mean square error.
To address the challenge posed by noise in real quantum devices, quantum error mitigation techniques play a crucial role. These techniques are resource-efficient, making them suitable for implementation in noisy intermediate-scale quantum devices, unlike the more resource-intensive quantum error correction codes. A notable example of such a technique is Clifford Data Regression, which employs a supervised learning approach. This work investigates two variants of this technique, both of which introduce a non-trivial set of gates into the original circuit. The first variant uses multiple copies of the original circuit, while the second adds a layer of single-qubit rotations. Different characteristics of these methods are analyzed theoretically, such as their complexity, or the scaling of the error with various parameters. Additionally, the performance of these methods is evaluated through numerical experiments, demonstrating a reduction in root mean square error.
In addressing the challenge posed by noise in actual quantum devices, the application of quantum error mitigation techniques becomes essential. These techniques are resource-efficient, making them viable for implementation in noisy intermediate-scale quantum devices, unlike the resource-intensive quantum error correction codes. A prominent example among these techniques is Clifford Data Regression, which employs a supervised learning approach. This work explores two variants of this technique, both of which add a non-trivial set of gates to the original circuit. The first variant leverages copies of the original circuit, whereas the second approach adds a layer of 1-qubit rotations.
Error mitigation is essential for the practical implementation of quantum algorithms on noisy intermediate-scale quantum (NISQ) devices. This work explores and extends Clifford Data Regression (CDR) to mitigate noise in quantum chemistry simulations using the Variational Quantum Eigensolver (VQE). Using the H4_44​ molecule with the tiled Unitary Product State (tUPS) ansatz, we perform noisy simulations with the ibm torino noise model to investigate in detail the effect of various hyperparameters in CDR on the error mitigation quality. Building on these insights, two improvements to the CDR framework are proposed. The first, Energy Sampling (ES), improves performance by selecting only the lowest-energy training circuits for regression, thereby further biasing the sample energies toward the target state. The second, Non-Clifford Extrapolation (NCE), enhances the regression model by including the number of non-Clifford parameters as an additional input, enabling the model to learn how the noisy-ideal mapping evolves as the circuit approaches the optimal one. Our numerical results demonstrate that both strategies outperform the original CDR.
Quantum error mitigation (QEM) is critical for harnessing the potential of near-term quantum devices. Particularly, QEM protocols can be designed based on machine learning, where the mapping between noisy computational outputs and ideal ones can be learned on a training set consisting of Clifford circuits or near-Clifford circuits that contain only a limited number of non-Clifford gates. This learned mapping is then applied to noisy target circuits to estimate the ideal computational output. In this work, we propose a learning-based error mitigation framework called Clifford Perturbation Data Regression (CPDR), which constructs training sets by Clifford circuits with small perturbations. Specifically, these circuits are parameterized quantum circuits, where the rotation angles of the gates are restricted to a narrow range, ensuring that the gates remain close to Clifford gates. This design enables the efficient simulation of the training circuits using the Sparse Pauli Dynamics method. As a result, CPDR is able to utilize training sets with a better diversity to train the model, compared with previous learning-based QEM models that construct training sets with only Clifford or near-Clifford circuits. Numerical simulations on small-scale Ising model circuits demonstrate that the performance of CPDR dramatically outperforms that of existing methods such as Zero-Noise Extrapolation and learning-based Probabilistic Error Cancellation. Furthermore, using the experimental data from IBM's 127-qubit Eagle processor, our findings suggest that CPDR demonstrates improved accuracy compared to the original mitigation results reported in [Nature 618, 500 (2023)].
If noisy-intermediate-scale-quantum-era quantum computers are to perform useful tasks, they will need to employ powerful error mitigation techniques.Quasiprobability methods can permit perfect error compensation at the cost of additional circuit executions, provided that the nature of the error model is fully understood and sufficiently local both spatially and temporally.Unfortunately, these conditions are challenging to satisfy.Here we present a method by which the proper compensation strategy can instead be learned ab initio.Our training process uses multiple variants of the primary circuit where all non-Clifford gates are substituted with gates that are efficient to simulate classically.The process yields a configuration that is near optimal versus noise in the real system with its non-Clifford gate set.Having presented a range of learning strategies, we demonstrate the power of the technique both with real quantum hardware (IBM devices) and exactly emulated imperfect quantum computers.The systems suffer a range of noise severities and types, including spatially and temporally correlated variants.In all cases the protocol successfully adapts to the noise and mitigates it to a high degree.
The practical implementation of quantum algorithms on noisy intermediate-scale quantum devices encounters operational limitations due to decoherence and other sources of noise inherent in real hardware. To mitigate these errors while preserving the original functionality of the algorithm, shorter quantum circuits are therefore preferred. This motivates the development of effective quantum circuit optimization algorithms. Learning-based approaches have emerged as a leading candidate, yet existing autonomous agents remain inefficient, spending most of their training capacity rediscovering elementary reductions that deterministic rule-based methods already handle reliably. To address this challenge, we propose a reinforcement learning framework that embeds a deterministic Commutation-and-Reduction (CR) algorithm directly into the training environment. After every agent action, the CR algorithm automatically resolves elementary commutations and cancellations, enabling the agent to focus its learning capacity on the non-trivial optimizations where reinforcement learning adds real value. Empirical evaluation across two gate sets, the universal Clifford+T basis and the CNOT+Pauli basis, shows that RL+CR produces shorter circuits than a standard RL agent at all tested scales. We demonstrate that RL trained on smaller quantum circuits can be applied to larger quantum circuits. On 20-qubit Clifford+T circuits, five times larger than the training circuits, RL+CR removes twice as many gates as standard RL. This work provides a robust approach that could accelerate the compilation and optimization processes for future fault-tolerant and utility-scale quantum systems.