Abstract Leukemia is a life-threatening blood cancer that requires early and accurate diagnosis to improve patient outcomes. Traditional diagnostic methods based on manual examination of blood smear images are time-consuming and prone to human error. With the advancement of artificial intelligence, automated detection systems using machine learning and deep learning techniques have shown promising results. However, classical models face limitations in handling complex feature spaces efficiently. To address this, this project proposes a hybrid approach titled “Leukemia Detection using Quantum Machine Learning”, which integrates classical image processing with quantum computing techniques. In this work, microscopic blood smear images from a publicly available Acute Lymphoblastic Leukemia dataset are utilized. The images undergo preprocessing steps including resizing, noise removal using Gaussian filtering, and normalization to enhance data quality. A Convolutional Neural Network (CNN) is employed for classical feature extraction, transforming image data into meaningful feature vectors. These features are further reduced using Principal Component Analysis (PCA) to make them suitable for quantum processing. The reduced feature set is encoded into quantum states using both angle encoding and amplitude encoding techniques. Quantum properties such as superposition and entanglement are leveraged through parameterized quantum circuits. Two quantum machine learning models, namely Quantum Support Vector Machine (QSVM) and Quantum Neural Network (QNN), are implemented to perform multi-class classification of leukemia stages, including Benign, Early, Pre, and Pro. The performance of both models is evaluated and compared using metrics such as accuracy, confusion matrix, and classification report. The proposed hybrid classical-quantum framework demonstrates the potential of quantum machine learning in medical image analysis. By combining deep learning with quantum algorithms, the system aims to improve diagnostic accuracy and computational efficiency. This approach not only enhances leukemia detection but also highlights the applicability of quantum computing in real-world healthcare problems, paving the way for future advancements in intelligent medical diagnosis systems.
Abstract Leukemia is a life-threatening blood cancer that requires early and accurate diagnosis to improve patient outcomes. Traditional diagnostic methods based on manual examination of blood smear images are time-consuming and prone to human error. With the advancement of artificial intelligence, automated detection systems using machine learning and deep learning techniques have shown promising results. However, classical models face limitations in handling complex feature spaces efficiently. To address this, this project proposes a hybrid approach titled “Leukemia Detection using Quantum Machine Learning”, which integrates classical image processing with quantum computing techniques. In this work, microscopic blood smear images from a publicly available Acute Lymphoblastic Leukemia dataset are utilized. The images undergo preprocessing steps including resizing, noise removal using Gaussian filtering, and normalization to enhance data quality. A Convolutional Neural Network (CNN) is employed for classical feature extraction, transforming image data into meaningful feature vectors. These features are further reduced using Principal Component Analysis (PCA) to make them suitable for quantum processing. The reduced feature set is encoded into quantum states using both angle encoding and amplitude encoding techniques. Quantum properties such as superposition and entanglement are leveraged through parameterized quantum circuits. Two quantum machine learning models, namely Quantum Support Vector Machine (QSVM) and Quantum Neural Network (QNN), are implemented to perform multi-class classification of leukemia stages, including Benign, Early, Pre, and Pro. The performance of both models is evaluated and compared using metrics such as accuracy, confusion matrix, and classification report. The proposed hybrid classical-quantum framework demonstrates the potential of quantum machine learning in medical image analysis. By combining deep learning with quantum algorithms, the system aims to improve diagnostic accuracy and computational efficiency. This approach not only enhances leukemia detection but also highlights the applicability of quantum computing in real-world healthcare problems, paving the way for future advancements in intelligent medical diagnosis systems.
Leukemia is a critical blood-related health problem for which early diagnosis is a key aspect in the survival of the patient. Computer-assisted diagnosis using microscopic white blood cell images has received significant attention because the conventional manual approach is too time-consuming. In this paper, a hybrid Quantum Machine Learning-based approach for the classification of leukemia is presented. In the first place, the microscopic white blood cell images are preprocessed using resizing, normalization, and denoising techniques. Then, Principal Component Analysis is applied for dimensionality reduction. The reduced feature vectors are then mapped onto a quantum system using a Variational Quantum Circuit-based Quantum Neural Network.The presented method also validates the possibility of quantum-assisted learning in biomedical image diagnosis. Additionally, it offers a glimpse of how well a hybrid model would perform under Noisy Intermediate-Scale Quantum (NISQ) conditions. The experimental results are achieved using standard performance parameters such as accuracy, precision, recall, and F1-score. This method indicates how a hybrid model of QML can perform in a computationally simpler manner. This paper also indicates the potential of a quantum-classical system in future clinical applications for leukemia screening and diagnosis.
Breast cancer is one of the most prevalent and life-threatening diseases affecting women worldwide, and early detection plays a crucial role in improving survival rates and treatment outcomes.Conventional diagnostic methods such as mammography, ultrasound imaging, and histopathological analysis rely heavily on expert interpretation and classical machine learning techniques.Although classical deep learning models, especially Convolutional Neural Networks (CNNs), have demonstrated impressive performance in medical image analysis, they face inherent limitations related to computational complexity, scalability, and the curse of dimensionality when handling large, high-resolution datasets.With the rapid advancement of quantum computing, Quantum Machine Learning (QML) has emerged as a promising paradigm capable of addressing these challenges by leveraging quantum phenomena such as superposition and entanglement.This research explores the application of Quantum Convolutional Neural Networks (Quantum CNNs or QCNNs) for breast cancer detection, aiming to enhance classification accuracy while reducing computational overhead.The proposed approach integrates quantum circuits with classical preprocessing techniques to extract discriminative features from breast cancer datasets, such as mammographic or histopathological images.By encoding image features into quantum states and performing convolution operations through parameterized quantum circuits, the Quantum CNN model is designed to learn complex patterns more efficiently than classical counterparts.The study evaluates the effectiveness of Quantum CNNs in distinguishing between benign and malignant breast tumors and compares its performance with traditional CNN models.The findings highlight the potential of Quantum CNNs to revolutionize medical image analysis by offering faster convergence, improved generalization, and robustness against noise.This research contributes to the growing field of quantumassisted healthcare systems and demonstrates how quantum computing can be harnessed to address critical challenges in breast cancer diagnosis.
Cancer remains one of the leading causes of mortality worldwide, making early and accurate detection a critical challenge in medicine. Recent advances in quantum computing have opened new avenues for enhancing machine learning techniques in medical imaging and diagnosis. In this work, we apply quantum machine learning models, including Quantum Convolutional Neural Networks (QCNN), to the task of breast cancer detection using ultrasound images. We designed and implemented a hybrid pipeline combining classical preprocessing techniques with quantum-enhanced classification. Our experiments were conducted on real medical imaging datasets, and the results demonstrate the potential of quantum approaches to improve diagnostic accuracy over classical baselines. This research lies at the intersection of quantum computing, artificial intelligence, and medical image analysis, and highlights the promise of quantum-enhanced methods in addressing complex healthcare problems.
Quantum-Enhanced Machine Learning (QEML) is a new computational paradigm that introduces the concept of quantum mechanics with the latest artificial intelligence algorithms to enhance the performance of the diagnostic process in the field of medical imaging. The early identification of diseases is crucial in mortality reduction and improving patient outcome, especially in capacities dealing with such diseases as cancer, neurological diseases, heart diseases, and infections of the lungs. Although conventional deep learning architectures, in particular, Convolutional Neural Networks (CNNs) have been highly successful in processing complex medical images such as MRI scans, CT images, X-rays, and histopathological data, they can be computationally expensive, need large data sets, and suffer in optimization of high dimensional feature spaces. The limitations that QEML tries to overcome are based on the quantum mechanical principles of superposition, entanglement and interference to facilitate better data representation and processing. The suggested structure is based on the classical deep learning architectures and variational quantum circuits together, to create a hybrid quantum-classical system, which improves features extraction and classification levels. Under this method, the classical image characteristics are coded into quantum states and processed in high-dimensional Hilbert spaces, which can enhance the separability of subtle disease patterns, which would have otherwise been challenging to obtain with conventional techniques. The objective of this hybrid system is to enhance the critical diagnostic measures like sensitivity and specificity without affecting the interpretability of such measures to be used in the clinical context. The proposed framework is also assessed in terms of its feasibility, its computational performance and scalability to the capabilities of present-day Noisy Intermediate-Scale Quantum (NISQ) devices. The model effectiveness is evaluated using objective evaluation metrics, which, in a way, guarantee the feasibility of the model application within a real-life healthcare context. On balance, quantum computing and medical image analysis integration is an exciting field of work of the future intelligent healthcare systems and has a potential of providing more efficient, accurate, and scalable diagnostic solutions.
Image classification has become a fundamental task in computer vision with applications in areas such as medical imaging, agriculture, environmental monitoring, and automated surveillance. Traditional machine learning techniques have achieved reasonable performance in classification tasks; however, they often struggle when dealing with high-dimensional and complex image datasets. Deep learning models, particularly Convolutional Neural Networks (CNNs), have significantly improved image classification performance by automatically learning hierarchical feature representations. Despite these advancements, classical deep learning models may still face challenges related to computational complexity and large-scale data processing.In recent years, quantum machine learning has emerged as a promising paradigm that combines principles of quantum computing with classical machine learning techniques to enhance computational efficiency and model performance. This study proposes a hybrid quantum–classical framework for image classification that integrates a deep residual network (ResNet-50) with a Quantum Support Vector Machine (QSVM). The ResNet-50 model is employed as a feature extraction mechanism to capture high-level visual representations from image data. The extracted features are then reduced in dimensionality using Principal Component Analysis (PCA) to simplify the feature space and improve computational efficiency.The reduced feature vectors are subsequently classified using a QSVM model that utilizes quantum feature maps to encode classical data into quantum states. Various quantum feature maps are explored to evaluate their impact on classification performance. Experimental results demonstrate that the hybrid quantum–classical approach achieves higher classification accuracy compared to conventional machine learning models such as Support Vector Machines and Random Forest classifiers. The proposed framework highlights the potential of combining classical deep learning architectures with quantum machine learning algorithms to address complex image classification challenges. This hybrid approach provides an efficient and scalable solution for advanced image analysis tasks and demonstrates the growing potential of quantum computing in artificial intelligence applications.
Blood group classification is a critical aspect of medical diagnostics, essential for transfusion medicine, organ transplantation and prenatal care.Traditional serological methods while effective, are time-consuming, require specialized laboratory facilities and are subject to human error.This research introduces a novel quantum-enhanced approach to blood group classification that combines deep learning techniques with quantum machine learning algorithms.Our methodology leverages convolutional neural networks (CNNs) optimized through quantum computing principles to analyze blood sample images for accurate and rapid blood group determination.Using a comprehensive dataset of 10,000 blood sample images across eight blood groups (A+, A-, B+, B-, AB+, AB-, O+, O-), we developed and validated our hybrid quantum-classical model.The proposed quantum-enhanced CNN achieved 99.5% classification accuracy, outperforming traditional serological methods (95.0%) and conventional machine learning approaches such as SVM (97.5%) and Random Forest (98.0%).Processing time was significantly reduced from 300 seconds for traditional methods to just 3.5 seconds for our quantum-enhanced approach.We further evaluated various CNN architectures with ResNet50 demonstrating the highest accuracy (99.0%) among classical implementations.The quantum advantage was particularly evident with larger datasets, showing consistent performance improvements across all testing scenarios.Our approach addresses critical gaps in current blood typing methodologies by providing a non-invasive, rapid and highly accurate alternative that can be deployed in resource-limited settings and emergency situations.This research demonstrates the practical application of quantum computing principles in healthcare diagnostics and establishes a foundation for further exploration of quantum-enhanced medical image analysis [1][2][3] .