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Advances in computational intelligence and robotics book series

Integration of Hybrid Quantum–Neuromorphic AI With Cloud, Edge, and High-Performance Computing Environments

Arun B Prasad, Ajay Prasad, Dineshkumar Rajendran, Anurag Tiwari, T. Akilan, Islombek Khushvaktov

Published Mar 4, 2026• 0 citations
Publisher

Abstract

The convergence of quantum computing, neuromorphic learning, and distributed cloud infrastructures has occurred very rapidly, and intelligent systems are now providing new opportunities, but the challenge of instability, complexity of orchestration, and noise sensitivity remains in the way of practical integration. The proposed work is based on a hybrid quantum and neuromorphic architecture, which is the integration of event-based neuromorphic adaptation and quantum-assisted global optimization, orchestrated by cloud-HPC. The architecture presents the thermodynamically regularized learning and resourceful task scheduling to the probabilistic search and the continuous local adaptation. Experimental evaluation across financial modeling, medical imaging, and physical system prediction shows an average accuracy of 94.3%, a reduction in convergence time to 3.5 s, and improved reconstruction quality (SSIM = 0.93, PSNR = 33.0 dB). Workflow robustness also increases, achieving a 96.1% task success rate under secure orchestration.

DOI
10.4018/979-8-3373-7779-7.ch007

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The convergence of quantum computing, neuromorphic learning, and distributed cloud infrastructures has occurred very rapidly, and intelligent systems are now providing new opportunities, but the challenge of instability, complexity of orchestration, and noise sensitivity remains in the way of practical integration. The proposed work is based on a hybrid quantum and neuromorphic architecture, which is the integration of event-based neuromorphic adaptation and quantum-assisted global optimization, orchestrated by cloud-HPC. The architecture presents the thermodynamically regularized learning and resourceful task scheduling to the probabilistic search and the continuous local adaptation. Experimental evaluation across financial modeling, medical imaging, and physical system prediction shows an average accuracy of 94.3%, a reduction in convergence time to 3.5 s, and improved reconstruction quality (SSIM = 0.93, PSNR = 33.0 dB). Workflow robustness also increases, achieving a 96.1% task success rate under secure orchestration.
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Artificial intelligence has become a transformative technology for predictive modelling across scientific, industrial, financial, and healthcare applications. However, the increasing complexity of large-scale datasets, high-dimensional feature spaces, and computationally intensive learning algorithms has exposed significant limitations in conventional computing architectures. Recent developments in quantum computing and high-performance computing have created unprecedented opportunities to accelerate artificial intelligence by improving computational efficiency, optimization capability, and predictive accuracy. This paper presents a comprehensive study of a quantum-driven artificial intelligence framework that integrates quantum algorithms with high-performance computing infrastructure to enhance predictive modelling performance. The proposed framework combines quantum-enhanced optimization, parallel heterogeneous computing, distributed data processing, and hybrid machine learning architectures to address computational bottlenecks encountered in conventional predictive systems. The study reviews recent developments in quantum artificial intelligence, evaluates emerging computational paradigms, identifies current research challenges, and proposes a scalable architecture suitable for future intelligent decision-support systems. The findings demonstrate that integrating quantum computation with high-performance computing can significantly improve prediction quality, optimization efficiency, scalability, and computational sustainability across diverse application domains while establishing a foundation for next-generation intelligent computing environments.
This chapter discusses the intersection of quantum computing, artificial intelligence and neuromorphic engineering as a basis of the next generation hybrid intelligent systems. It describes the role of quantum processing in providing high-dimensional reasoning and probabilistic optimization, and the ability of neuromorphic hardware to do spiking computations at real time and using less energy. These paradigms and their combination address the scalability and performance constraints of classical AI. The chapter examines major hybrid architectures, neuromorphic-to-quantum encoding algorithms, quantum-assisted learning algorithms, and integrated inference pipelines. Another significant aspect that it brings to the fore is the key areas of application, including robotics, healthcare, finance, and edge intelligence, as well as engineering limitations, moral implications, and safety issues of AGI. An outlook research road identifies essential milestones towards scalable, secure, and interpretable hybrid neuromorphic quantum systems.
Neuromorphic computing is inspired by the dynamics of biological neural systems - they operate event-driven and enable energy-efficient and real-time learning by Spiking neural networks. Advantages of this approach include faster convergence, improved accuracy, and potential energy efficiency gain, making this approach suitable for edge AI, real-time signal processing, and large-scale cognitive simulations. The convergence of neuromorphic computing and quantum optimization offers a transformative pathway for next-generation AI. By integrating event-driven spiking neural networks with quantum algorithms, hybrid systems can achieve faster learning, enhanced global optimization, and energy-efficient computation beyond classical limits. A comprehensive framework has been presented for designing and analyzing such hybrid quantum-neuromorphic architectures, highlighting their potential for real-time, scalable, and intelligent applications.
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High-performance computing (HPC) has evolved over decades through multiple architectural transitions, from vector supercomputers to massively parallel CPU clusters and GPU-accelerated systems, continuously expanding the frontier of scientific discovery. With the emergence of quantum processing units (QPUs) as practical computational accelerators, a new opportunity arises to further extend this trajectory by integrating quantum and classical computing paradigms. Building on the emerging vision of Quantum Integrated High-Performance Computing (QHPC), this paper contributes a full-stack layered architecture that integrates QPUs as first-class accelerators within, not merely alongside, the classical HPC software and hardware stack, with tight, on-premise quantum-classical coupling as its defining characteristic. The architecture comprises of unified resource management, quantum-aware scheduling, hybrid workflow orchestration, middleware and programming abstraction, interconnect technologies, and a tiered execution model enabling seamless workload partitioning across classical and quantum backends. A central aspect of this architecture is a strong user requests abstraction layer that exposes heterogeneous resources through a unified job submission interface, similar in spirit to existing schedulers such as Slurm, allowing users to describe workloads in a consistent template independent of underlying compute type or location. Drawing insights from prior accelerator integration eras, we outline how QHPC can support emerging workloads in quantum chemistry, materials discovery, combinatorial optimization, and climate modeling. We conclude by highlighting open challenges in building scalable, reliable, and programmable quantum-classical infrastructures that seamlessly connect global users to heterogeneous compute resources for future quantum-classical HPC ecosystems.