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Quantum Computing Meets Large Language Models: Insights, Challenges, and Future Directions

Thippa Reddy Gadekallu, Kai Fang, Hailin Feng, Wei Wang, Yuchao Xia, Jijing Cai, Engin Zeydan, Pronaya Bhattacharya, Chamitha de Alwis, Madhusanka Liyanage

Published Feb 2, 2026• 0 citations
Publisher

Abstract

Large Language Models (LLMs) such as GPT and LLaMA have transformed artificial intelligence, but their rapid growth has brought major challenges in computation, energy use, and scalability. Quantum computing (QC) offers a fundamentally different way to process information, with the potential to accelerate key operations in training, inference, optimization, and representation learning. This survey provides a structured and comprehensive review of how QC can support the future development of LLMs. It examines quantum algorithms, hybrid quantum-classical methods, quantum neural networks, quantum embeddings, and security applications. It also evaluates their feasibility in both the current noisy intermediate-scale quantum (NISQ) era and the future fault-tolerant era. The survey highlights current progress, identifies major technical barriers, and outlines practical research directions needed to build scalable, efficient, and secure quantum-enhanced language models.

DOI
10.36227/techrxiv.177004376.69666864/v1

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Large Language Models (LLMs) such as GPT and LLaMA have transformed artificial intelligence, but their rapid growth has brought major challenges in computation, energy use, and scalability. Quantum computing (QC) offers a fundamentally different way to process information, with the potential to accelerate key operations in training, inference, optimization, and representation learning. This survey provides a structured and comprehensive review of how QC can support the future development of LLMs. It examines quantum algorithms, hybrid quantum-classical methods, quantum neural networks, quantum embeddings, and security applications. It also evaluates their feasibility in both the current noisy intermediate-scale quantum (NISQ) era and the future fault-tolerant era. The survey highlights current progress, identifies major technical barriers, and outlines practical research directions needed to build scalable, efficient, and secure quantum-enhanced language models.
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Significant computational challenges exist in the training of large language models (LLMs), specifically for the efficient convergence. This paper discusses a hybrid quantum-classical framework designed to address these challenges. With the integration of quantum computing principles, like the superposition, entanglement, and tunneling, into the classical deep learning methods, an approach is studied to accelerate convergence, enhance optimization efficiency, and improve model generalization. A quantum feature mapping is used to project classical data into high-dimensional Hilbert spaces, enhancing data representation and revealing more complex feature patterns in the data. The quantum-assisted optimization algorithms, like Quantum Approximate Optimization Algorithm (QAOA) and Variational Quantum Eigensolver (VQE), can efficiently find optimal solutions within complex, non-convex loss landscapes and mitigate the issues of local minima encountered by classical methods. Furthermore, the quantum-accelerated matrix operations, with the use of Harrow-Hassidim-Lloyd (HHL) algorithm or Quantum Fourier Transform (QFT) etc., can provide computational speed-ups for the LLM training. Quantum measurement introduces inherent randomness, similar to the dropout in deep neural networks, where certain neurons are randomly deactivated during training. In the noisy intermediate-scale quantum (NISQ) era, our quantum-classical framework and conceptual analyses demonstrate the feasibility and potential advantages. This work lays the foundation for future research in this area.
Quantum computing has emerged as a transformative paradigm capable of addressing computational challenges beyond the reach of classical systems.In the current era of Noisy Intermediate-Scale Quantum (NISQ) devices, practical quantum hardware is characterized by limited qubit counts, short coherence times, gate errors, and the absence of full error correction.Despite these constraints, significant progress has been made in developing quantum machine learning (QML) techniques tailored to operate on near-term quantum processors.This paper presents a comprehensive review of Quantum Machine Learning in the context of NISQ computing.We first outline the fundamental principles of quantum computing, including qubits, superposition, entanglement, and quantum parallelism, followed by a detailed discussion of the NISQ computing model and its hardware limitations.The review then examines hybrid quantum-classical learning frameworks, variational quantum algorithms, quantum data encoding strategies, and noise mitigation techniques that enable practical implementation on existing platforms.Emerging applications across healthcare, finance, cybersecurity, climate modeling, and materials science are also surveyed to highlight the real-world potential of QML.Furthermore, key challenges such as scalability, trainability issues, and algorithmic robustness are analyzed, along with current research efforts aimed at overcoming these barriers.The paper concludes by identifying promising future directions for advancing QML toward quantum advantage.This review aims to provide researchers and practitioners with a structured understanding of the capabilities, limitations, and opportunities of quantum machine learning in the NISQ era .
Quantum Machine Learning represents a paradigm shift at the intersection of Quantum Computing and Machine Learning, leveraging quantum phenomena such as superposition, entanglement, and quantum parallelism to address the limitations of classical approaches in processing high-dimensional and large-scale datasets. This survey provides a comprehensive analysis of Quantum Machine Learning, detailing foundational concepts, algorithmic advancements, and their applications across domains such as healthcare, finance, and quantum chemistry. Key techniques, including Quantum Support Vector Machine, Quantum Neural Network, Quantum Decision Trees, and hybrid quantum-classical models, are explored with a focus on their theoretical foundations, computational benefits, and comparative performance against classical counterparts. While the potential for exponential speedups and enhanced efficiency is evident, the field faces significant challenges, including hardware constraints, noise, and limited qubit coherence in the current era of Noisy Intermediate-Scale Quantum devices. Emerging solutions, such as error mitigation techniques, hybrid frameworks, and advancements in quantum hardware, are discussed as critical enablers for scalable and fault-tolerant Quantum Machine Learning systems. By synthesizing state-of-the-art developments and identifying research gaps, this survey aims to provide a foundational resource for advancing Quantum Machine Learning toward practical, real-world applications in tackling computationally intensive problems.
Abstract Quantum computing has immense potential to advance the field of Artificial Intelligence (AI), promising faster processing, better optimization, and the ability to handle complex data structures more effectively. However, several challenges need to be addressed, including hardware limitations, algorithm development, and integration with existing AI workflows. This work provides a comprehensive overview of the current state of quantum AI research, covering key areas such as quantum machine learning, quantum deep learning, quantum natural language processing, quantum problem solving, quantum fuzzy logic, quantum evolutionary computation, and quantum decision making. It also presents a collection of interesting use cases targeted at different vertical sectors. The research methodology involves a thorough literature review to capture the most impactful developments from the standpoint of algorithm scalability in the 2020–2024 timeframe. The review highlights the benefits of quantum approaches, such as improved learning capacity, robustness to overfitting and, in some specific cases, quantum speedups for solving various problems. The interdisciplinary research landscape demonstrates a discernible trajectory toward the implementation of practical, large‐scale quantum computational intelligence. This progression is contingent upon the adoption of scalable algorithms that can deliver a quantum advantage, diverging from the replication of classical AI workflows.