Quantum correlation imaging via X-ray parametric down-conversion
Justin C. Goodrich, Ryan Mahon, Joseph Hanrahan, Dennis Bollweg, Monika Dziubelski, Raphael A. Abrahão, Sanjit Karmakar, K. Gofron, Thomas A Caswell, Daniel Allan, Lonny E. Berman, ANDREI NOMEROTSKI, Andrei Fluerasu, C. Da Vià, Sean M. McSweeney
Quantum imaging leverages correlations between pairs of photons and has the potential to obtain image information beyond what classical sources provide. Extending this approach to the X-ray regime has been limited by low photon-pair generation rates and the lack of suitable detectors. Here, we demonstrate X-ray coincidence imaging using spontaneous parametric down-conversion (SPDC) and a pixelated area detector with time- and energy-resolved capabilities. This configuration enables simultaneous detection of correlated X-ray photon pairs and coincidence-based imaging of test objects, including a biological specimen. The increased coincidence rate and spatially resolved detection establish a basis for future quantum-enhanced and low-dose X-ray imaging.
Quantum imaging leverages correlations between pairs of photons and has the potential to obtain image information beyond what classical sources provide. Extending this approach to the X-ray regime has been limited by low photon-pair generation rates and the lack of suitable detectors. Here, we demonstrate X-ray coincidence imaging using spontaneous parametric down-conversion (SPDC) and a pixelated area detector with time- and energy-resolved capabilities. This configuration enables simultaneous detection of correlated X-ray photon pairs and coincidence-based imaging of test objects, including a biological specimen. The increased coincidence rate and spatially resolved detection establish a basis for future quantum-enhanced and low-dose X-ray imaging.
Quantum imaging encompasses a broad range of methods that exploit the quantum properties of light to capture information about an object. One such approach involves using a two-photon quantum state, where only one photon interacts with the object being imaged while its entangled partner carries spatial or temporal information. To implement this technique, it is necessary to generate specific quantum states of light and detect photons at the single-photon level. While this method has been successfully demonstrated in the visible electromagnetic spectrum, extending it to X-rays has faced significant challenges due to the difficulties in producing a sufficient rate of X-ray photon pairs and detecting them with adequate resolution. Here, we demonstrate record high rates of correlated X-ray photon pairs produced via a spontaneous parametric down-conversion process and we employ these photons to perform quantum correlation imaging of several objects, including a biological sample (E. cardamomum seedpod). Notably, we report an unprecedented detection rate of about 6,300 pairs per hour and the observation of energy anti-correlation for the X-ray photon pairs. We also present a detailed analysis of the properties of the down-converted X-ray photons, as well as a comprehensive study of the correlation imaging formation, including a study of distortions and corrections. These results mark a substantial advancement in X-ray quantum imaging, expanding the possibilities of X-ray quantum optical technologies, and illustrating the pathway towards enhancing biological imaging with reduced radiation doses.
We directly observe far-field correlations of x-ray photon pairs generated by spontaneous parametric down-conversion (SPDC). Using an energy-resolved, two-dimensional photon counting detector we record the full ring-shaped emission of both photons across a broad bandwidth and extract pair correlations directly from raw events without imposing angular constraints. The ring radii scale with photon energy, in quantitative agreement with transverse phase matching, providing a stringent momentum-space validation of x-ray SPDC. These observations open a route to leveraging quantum correlations in x-ray imaging and metrology, including correlation-enhanced magnification and reduced blurring.
Spontaneous parametric down-conversion is a vital method for generating correlated photon pairs in the visible and near-infrared spectral regions; however, its extension to X-ray frequencies has faced substantial barriers. Here, we present an advancement in correlated X-ray pair generation and detection by employing a two-dimensional pixelated detector to obtain the first direct image of the pair distribution. Our study explores and directly visualizes the down-conversion process, revealing the characteristic ring structure of coincident photon pairs and demonstrating robust spatial correlations. A significant finding is the observation of energy anti-correlation, achieved at an unprecedented rate of approximately 4,100 pairs/hour, far exceeding previous reports in the literature. We believe these results represent a significant leap in X-ray quantum imaging, unlocking the potential for enhanced imaging of biological materials with reduced doses and broadening the applicability of X-ray quantum optical technologies.
Classical light sources emit a randomly-timed stream of individual photons, the spatial distribution of which can be detected with a camera to form an image. Quantum light sources, based on parametric down conversion, emit photons as correlated photon-pairs. The spatial correlations between the photons enables imaging systems where the preferential selection of photon-pairs allows for enhancements in the noise performance over what is possible using classical light sources. However, until now the technical challenge of measuring, and correlating both photons has led to system complexity. Here we show that a camera capable of resolving the number of individual photons in each pixel of the detector array can be used to record an image formed from these photon-pair events and hence achieve a greater contrast than possible using a classical light source. We achieve an enhancement in the ratio of two-photon events compared to one-photon events using spatially correlated SPDC light compared to uncorrelated illumination by a LED. These results indicate the potential advantages of using photon counting cameras in quantum imaging schemes and these advantages will further increase as the technology is developed. Operating in photon sparse regimes such systems have potential applications in low-light microscopy and covert imaging.
Imaging with X-rays poses fundamental limits due to radiation damage of the highly energetic photons. This becomes problematic for sensitive biological systems such as subcellular structures. Lowering the radiation dose, without sacrificing the signal-to-noise ratio, would be desirable for any kind of imaging modalities involving X-rays. To achieve this goal, quantum imaging with entangled X-ray photons constitutes a promising route. Production of biphotons have been demonstrated in the X-ray regime by the process of Spontaneous Parametric Down-Conversion (SPDC). However, compared to SPDC in the regime of visible light, the production rate for X-ray biphotons is extremely low. With the introduction of new high average brightness X-ray sources, such as 4th generation synchrotrons and high repetition rate Free-Electron X-ray Lasers (XFEL), quantum imaging may become practical. We introduce a ray tracing approach using Monte-Carlo sampling, specifically designed for quantum imaging with entangled X-ray photons generated by SPDC. By simulation, the superior image quality of quantum over classical imaging methods is demonstrated using realistic experimental conditions available at high repetition rate XFELs. With these simulations, we can efficiently assist the design of future experiments at beam lines, which can substantially accelerate the advancement of X-ray quantum imaging and reduce costs.
Quantum imaging leverages nonclassical correlations to reveal features that may vanish in conventional event integration [ 1, 2]. While single-photon detectors are well-established, quantum imaging demands complex data acquisition across many thousands of detectors, each generating rich metadata including triggering time, duration, and other properties. Consequently, effective data management, data wrangling, and correlation extraction become critical challenges. In this work, we investigate optimal handling of spatial correlations from a quantum-photonic source (spontaneous parametric down-conversion, SPDC) using an emerging single-photon event-based camera, the TPX3CAM (256×256 array, supported by an intensifier). Utilizing a femtosecond photon-pair source, we comprehensively analyse noise characteristics, including temporal dynamics and spatial distribution, to develop advanced spatio-temporal noise suppression strategies tailored to camera performance. Our primary objectives include real-time isolation and preprocessing of correlative data. Our analysis demonstrates the potential of these real-time correlation detection and noise reduction algorithms to expand quantum imaging capabilities across diverse scientific domains. Potential applications include high-resolution spectroscopy in biology, materials science, and advanced electron microscopy, where these techniques could enable identification of cascaded two-photon processes with atomic-scale precision. Figure 1 shows an excellent example of such a detection in real-space. The ring feature corresponds to the location of the correlated photon-pairs produced from the SPDC process. This is also apparent in figure 2, where we see a strong anti-correlation between the coordinates of the detected photons – corresponding to photon-pairs. <!-- named anchor --> Figure 1: Distribution of SPDC photons on TPX3CAM <!-- named anchor --> Figure 2: Spatial anti-correlation of x-coordinates