Cancer prognosis prediction faces challenges such as complex multimodal data and computational inefficiencies, leading to delayed clinical decisions. This paper proposes a novel hybrid quantum-classical neural network (HQNN) framework for enhanced predictive analytics in oncology. By integrating quantum variational circuits with classical convolutional neural networks (CNN) and real-time multimodal data (genomic and imaging), the framework achieves classification accuracy of 92. 5 %, outperforming traditional CNNs (80.5 %) and deep neural networks (DNNs, 85.5%) in the TCGA dataset. The methodology includes data preprocessing, quantum feature encoding, and real-time prediction. Tested on 10,340 samples across 33 cancer types, the HQNN reduces inference time by 20 % and improves accuracy by 12 % over baselines. This work underscores the potential of QNNs to transform precision oncology, enabling faster and more accurate prognosis predictions to support clinical decision-making.
Cancer prognosis prediction faces challenges such as complex multimodal data and computational inefficiencies, leading to delayed clinical decisions. This paper proposes a novel hybrid quantum-classical neural network (HQNN) framework for enhanced predictive analytics in oncology. By integrating quantum variational circuits with classical convolutional neural networks (CNN) and real-time multimodal data (genomic and imaging), the framework achieves classification accuracy of 92. 5 %, outperforming traditional CNNs (80.5 %) and deep neural networks (DNNs, 85.5%) in the TCGA dataset. The methodology includes data preprocessing, quantum feature encoding, and real-time prediction. Tested on 10,340 samples across 33 cancer types, the HQNN reduces inference time by 20 % and improves accuracy by 12 % over baselines. This work underscores the potential of QNNs to transform precision oncology, enabling faster and more accurate prognosis predictions to support clinical decision-making.
Breast cancer diagnosis through thermographic image analysis remains a critical challenge in medical AI, with classical deep learning approaches facing limitations in complex thermal pattern classification tasks. This paper presents a novel Hybrid Quantum Neural Network (HQNN) architecture that integrates quantum computing principles with classical convolutional neural networks for enhanced breast cancer classification. Our approach employs parameterized quantum circuits with multi-head attention mechanisms for quantum-aware feature encoding, coupled with classical convolutional layers for comprehensive pattern recognition. The quantum component utilizes a 4qubit variational circuit with strongly entangling layers, while the classical component incorporates advanced attention mechanisms for feature fusion. Experimental validation on breast cancer thermographic data demonstrates substantial performance improvements over state-of-the-art classical architectures, with the quantum-enhanced approach exhibiting superior convergence dynamics and enhanced feature representation capabilities. Our findings provide evidence for quantum advantage in medical image classification through classical simulation, establishing a framework for quantum-classical hybrid systems in healthcare applications. The methodology addresses key challenges in quantum machine learning deployment while maintaining computational feasibility on near-term quantum devices.
Breast cancer remains a critical global health challenge, underscoring the need for early and precise diagnostic methodologies. This paper proposes a novel hybrid deep learning framework that integrates Quantum Neural Networks (QNNs) with the ResNet152 architecture and Transfer Learning to enhance breast cancer classification from medical images. Leveraging the feature extraction power of a pre-trained ResNet152 model, the system encodes refined feature representations into a parameterized quantum circuit utilizing Hadamard, CNOT, and Ry gates. Quantum error correction strategies such as Shor’s Code and surface code are incorporated to preserve quantum state fidelity and reduce decoherence-induced errors, thereby enhancing model robustness. Furthermore, quantum transfer learning accelerates training convergence and enriches pattern recognition capability in high-dimensional medical data. The proposed hybrid model achieves a classification accuracy of 97% and a real-time inference rate of 0.032 frames per second when deployed on an AI edge device, validating its efficacy for point-of-care diagnostics. This study underscores the transformative potential of synergizing quantum computing, edge AI, and deep learning to deliver scalable, interpretable, and high-precision diagnostic tools for clinical applications. The promising results open new avenues for integrating quantum technologies into conventional neural architectures to address the challenges of medical imaging and diagnostic intelligence.
Introduction: Medical image classification is a crucial task in cancer diagnosis, relying on the accurate analysis of high-dimensional imaging data. While Convolutional Neural Networks (CNNs) have shown great success in this domain, their performance is often limited by the shallow feature expressiveness and overfitting, particularly in small or heterogeneous datasets. Methods: Quantum machine learning offers new opportunities through high-dimensional representations and nonlinear transformations. In this work, we propose a Quantum-Enhanced Sandwich Convolutional Neural Network (QSCNN), a layered hybrid architecture that integrates quantum and classical modules. The model employs a quanvolutional layer for localized quantum feature extraction, followed by conventional convolution and pooling for hierarchical representation learning, and a variational quantum classifier for nonlinear decision-making. Results: QSCNN achieved higher accuracy and training stability than classical CNNs and QCCNN baselines across three medical imaging tasks.: brain tumor MRI, skin cancer dermoscopy, and lung cancer CT. Circuit depth analysis revealed a trade-off between expressiveness and robustness, and additional experiments with depolarizing noise confirmed the model’s resilience under realistic quantum error conditions. Discussion: This suggests that circuit design choices influence hybrid model behavior and generalization, supporting the feasibility of quantum-enhanced methods for small-sample medical imaging. However, the current evaluation is limited to relatively small benchmark datasets, and broader validation on large-scale data will be essential to confirm clinical applicability. Conclusion: In summary, QSCNN presents a feasible hybrid framework for enhancing medical image classification with quantum features. While preliminary, our results suggest potential advantages in accuracy and stability under NISQ conditions.
Breast cancer is one of the most prevalent and life-threatening diseases affecting women worldwide, and early detection plays a crucial role in improving survival rates and treatment outcomes.Conventional diagnostic methods such as mammography, ultrasound imaging, and histopathological analysis rely heavily on expert interpretation and classical machine learning techniques.Although classical deep learning models, especially Convolutional Neural Networks (CNNs), have demonstrated impressive performance in medical image analysis, they face inherent limitations related to computational complexity, scalability, and the curse of dimensionality when handling large, high-resolution datasets.With the rapid advancement of quantum computing, Quantum Machine Learning (QML) has emerged as a promising paradigm capable of addressing these challenges by leveraging quantum phenomena such as superposition and entanglement.This research explores the application of Quantum Convolutional Neural Networks (Quantum CNNs or QCNNs) for breast cancer detection, aiming to enhance classification accuracy while reducing computational overhead.The proposed approach integrates quantum circuits with classical preprocessing techniques to extract discriminative features from breast cancer datasets, such as mammographic or histopathological images.By encoding image features into quantum states and performing convolution operations through parameterized quantum circuits, the Quantum CNN model is designed to learn complex patterns more efficiently than classical counterparts.The study evaluates the effectiveness of Quantum CNNs in distinguishing between benign and malignant breast tumors and compares its performance with traditional CNN models.The findings highlight the potential of Quantum CNNs to revolutionize medical image analysis by offering faster convergence, improved generalization, and robustness against noise.This research contributes to the growing field of quantumassisted healthcare systems and demonstrates how quantum computing can be harnessed to address critical challenges in breast cancer diagnosis.
Breast cancer is one among the most common diseases that are encountered in the world and one of the principal causes of death among women, early detection being crucial to enhance survival rates but mammograms are an important tool that can save lives by finding breast cancer at its earliest stages but the manual evaluation is dependent on a radiologist's clear interpretation and analysis of which sometimes erroneously or misses the key findings. This research work deals with breast cancer detection from mammogram images and hence provides a solution for the issues identified by training Quantum Convolutional Neural Network (Quantum CNN). Quantum CNNs is recently being integrated with classical deep learning models in the form of Quantum CNN where quantum mechanical properties are used to support feature extraction and data handling. This research work trains the Quantum CNN using publicly available datasets, including the CBIS-DDSM Breast Cancer Image Dataset and the Breast Histopathology Images dataset. Key methods used include data preprocessing techniques such as Region of Interest (ROI) extraction, morphological operations, and quantum-enhanced convolutional layers for image classification. The proposed model demonstrates improved accuracy and computational efficiency over classical CNNs, making it a promising tool for more accurate and faster breast cancer detection.
Diagnosis of cancer is one of the hardest problems faced in modern medicine and involves integrating different data sources such as medical images, genomic profiles and clinical records. Traditional machine learning methods have difficulty handling the high-dimensional and complex correlation properties of multimodal medical data. In view of this, we propose a new Quantum-Enhanced Multimodal Fusion Network (QEMFN) framework to break through traditional image–text matching based on quantum computing principles for CT imaging with genomic sequencing data and EHR information. Our approach utilizes variational quantum circuits for feature encoding, quantum kernel methods for crossmodal attention, and hybrid quantum–classical architectures for final classification. We realize the framework using Google Cirq quantum computing library and validate it on publicly available datasets including TCIA (The Cancer Imaging Archive), TCGA (The Cancer Genome Atlas), and MIMIC-III clinical database. The matched multimodal cohort comprises 847 lung cancer patients, 623 colorectal cancer patients, and 401 liver cancer patients with complete imaging, genomic, and clinical records, assembled via de-identified patient ID linkage across the three archives. The experiment takes steps toward the realization of quantum-enhanced diagnostic systems and offers a path for subsequent experimental confirmation. We theoretically analyze the potential quantum advantage, present detailed implementation details using Cirq, and describe a roadmap to clinical translation for quantum-enhanced diagnostic tools.