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International Conference on Data Science and Its Applications (ICoDSA)

Hybrid Quantum-Classical Neural Network for Breast Cancer Detection

M. T. Rahim, Asad Ali, Tanvir Alam

Published Jul 3, 2025• 3 citations
Publisher

Abstract

Breast cancer is among the leading causes of mortality among women worldwide, emphasizing the urgent need for accurate and efficient diagnostic tools. Machine learning-based systems have been heavily investigated in this regard. Quantum computing has garnered considerable attention recently; however, few studies have focused on its application to this specific problem. In this work, we integrate quantum computing principles with classical neural networks (QCNNs) to enhance the detection accuracy and computational efficiency of breast cancer diagnosis using the MedMNIST dataset. The hybrid QCNN framework leverages the power of quantum computing to perform complex feature mapping and extraction while reducing the estimated circuit depth of the quantum circuit compared to pure quantum neural network schemes. The proposed model achieved an accuracy of over 84%, a sensitivity of 82%, and a specificity of 86.0%, outperforming the state-of-the-art model developed for the same purpose. The focus of the study is to improve the accuracy and generalizability of classifying complex mammograms, as opposed to current quantum machine learning models, for practical applications in healthcare. We believe this study will support advancing the prospect of AI-enabled medical diagnosis with state-of-the-art quantum computing principles.

DOI
10.1109/icodsa67155.2025.11157288

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Cancer remains one of the leading causes of mortality worldwide, making early and accurate detection a critical challenge in medicine. Recent advances in quantum computing have opened new avenues for enhancing machine learning techniques in medical imaging and diagnosis. In this work, we apply quantum machine learning models, including Quantum Convolutional Neural Networks (QCNN), to the task of breast cancer detection using ultrasound images. We designed and implemented a hybrid pipeline combining classical preprocessing techniques with quantum-enhanced classification. Our experiments were conducted on real medical imaging datasets, and the results demonstrate the potential of quantum approaches to improve diagnostic accuracy over classical baselines. This research lies at the intersection of quantum computing, artificial intelligence, and medical image analysis, and highlights the promise of quantum-enhanced methods in addressing complex healthcare problems.
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Breast cancer is one among the most common diseases that are encountered in the world and one of the principal causes of death among women, early detection being crucial to enhance survival rates but mammograms are an important tool that can save lives by finding breast cancer at its earliest stages but the manual evaluation is dependent on a radiologist's clear interpretation and analysis of which sometimes erroneously or misses the key findings. This research work deals with breast cancer detection from mammogram images and hence provides a solution for the issues identified by training Quantum Convolutional Neural Network (Quantum CNN). Quantum CNNs is recently being integrated with classical deep learning models in the form of Quantum CNN where quantum mechanical properties are used to support feature extraction and data handling. This research work trains the Quantum CNN using publicly available datasets, including the CBIS-DDSM Breast Cancer Image Dataset and the Breast Histopathology Images dataset. Key methods used include data preprocessing techniques such as Region of Interest (ROI) extraction, morphological operations, and quantum-enhanced convolutional layers for image classification. The proposed model demonstrates improved accuracy and computational efficiency over classical CNNs, making it a promising tool for more accurate and faster breast cancer detection.
This paper explores the potential of quantum ma-chine learning for breast cancer detection. We designed a binary classification approach using the BreastMNIST dataset and segmented mass regions derived from the BCDR dataset. A quanvolutional layer is employed as a quantum feature extractor, interfaced with elements of classical neural networks, to enhance the detection of malignant and benign patterns in breast tissue. The hybrid quanvolutional neural network aims to mitigate challenges associated with traditional machine learning models, such as feature sparsity and data imbalance. This architecture employs a simple yet efficient design that integrates the strengths of both quantum computing and classical methods, reducing computational complexity while maintaining performance. Re-sults demonstrate the potential of quanvolutions in diagnostic accuracy, offering a promising framework for integrating quan-tum computing in medical imaging. This approach provides an optimized solution that balances quantum processing with classical systems for more effective and scalable applications.