Nitrogen-vacancy (NV) centres are exceptional solid-state quantum sensors with optically addressable spins. With room-temperature operability and biocompatibility, functionalised NV centres in nanodiamonds facilitate atomic-scale tracking and real-time monitoring of physical and chemical properties within living systems [1]. Conventionally, these systems work by addressing stochastically-positioned defects with a complex bulk-optic microscope [2] or using a single scanning probe, limited in scalability and the ability to capture spatial and temporal information simultaneously.
Nitrogen-vacancy (NV) centres are exceptional solid-state quantum sensors with optically addressable spins. With room-temperature operability and biocompatibility, functionalised NV centres in nanodiamonds facilitate atomic-scale tracking and real-time monitoring of physical and chemical properties within living systems [1]. Conventionally, these systems work by addressing stochastically-positioned defects with a complex bulk-optic microscope [2] or using a single scanning probe, limited in scalability and the ability to capture spatial and temporal information simultaneously.
Abstract Powered by the mutual developments in instrumentation, materials and theoretical descriptions, sensing and imaging capabilities of quantum emitters in solids have significantly increased in the past two decades. Quantum emitters in solids, whose properties resemble those of atoms and ions, provide alternative ways to probing natural and artificial nanoscopic systems with minimum disturbance and ultimate spatial resolution. Among those emerging quantum emitters, the nitrogen vacancy (NV) color center in diamond is an outstanding example due to its intrinsic properties at room temperature (highly-luminescent, photo-stable, biocompatible, highly-coherent spin states). This review article summarizes recent advances and achievements in using NV centers within nano- and single crystal diamonds in sensing and imaging. We also highlight prevalent challenges and material aspects for different types of diamond and outline the main parameters to consider when using color centers as sensors. As a novel sensing resource, we highlight the properties of NV centers as light emitting electrical dipoles and their coupling to other nanoscale dipoles e.g. graphene.
This monograph presents the emerging field of second-generation quantum sensing, which leverages phenomena such as superposition and entanglement, thereby offering measurement sensitivities far surpassing classical methods. In our discussion, we emphasize its potential to revolutionize various scientific and technological domains. Starting with a foundational overview of quantum sensors, distinguishing them from quantum computing and communication technologies, we then highlight the relative maturity of quantum sensing, especially in room-temperature operations, which positions it closest to market adoption. The main part of the monograph is dedicated to solid-state defects, particularly nitrogen-vacancy (NV) centers in diamond, which have emerged as promising candidates for scalable quantum sensors. The unique optical and spin properties of NV centers are explored in detail, emphasizing their possible applications in fields such as biomedical imaging, materials science, and semiconductor inspection. We delve into the technical aspects of integrating NV centers with conventional electronic and photonic systems, discussing the challenges and innovations in electronic interface circuits, photonic integration, and system-level integration technologies. Additionally, we examine gas-based quantum sensors, particularly those utilizing Rydberg atoms, which offer high precision due to their long coherence times. The challenges of integrating gas-based sensors, compared to their solid-state counterparts, are also briefly discussed. Overall, the monograph underscores the potential of second-generation quantum sensors, particularly those based on NV centers, to be the first scalable, high-volume quantum devices on the market, with applications spanning various fields due to their high sensitivity and room-temperature operation.
Powered by the mutual developments in instrumentation, materials andtheoretical descriptions, sensing and imaging capabilities of quantum emitters insolids have significantly increased in the past two decades. Quantum emitters insolids, whose properties resemble those of atoms and ions, provide alternative waysto probing natural and artificial nanoscopic systems with minimum disturbance andultimate spatial resolution. Among those emerging quantum emitters, the nitrogen-vacancy (NV) color center in diamond is an outstanding example due to its intrinsicproperties at room temperature (highly-luminescent, photo-stable, biocompatible,highly-coherent spin states). This review article summarizes recent advances andachievements in using NV centers within nano- and single crystal diamonds in sensingand imaging. We also highlight prevalent challenges and material aspects for differenttypes of diamond and outline the main parameters to consider when using color centersas sensors. As a novel sensing resource, we highlight the properties of NV centersas light emitting electrical dipoles and their coupling to other nanoscale dipoles e.g.graphene.
Nitrogen-vacancy (NV) centres in diamond show great promise for quantum computing, where photonic entanglement can be generated using long-lived optically-active spins [1]. A quantum processor would require a large number of interconnected NV centres, and an integrated platform becomes necessary for control and routing. Benefits of integration include nanophotonic cavities with ultra-small mode volumes [2], multilayer electronics, and use of existing integrated quantum photonic components and architectures. Pick-and-place methods have been adopted to combine diamond microchiplets with aluminium nitride [3]. Photonic and spin properties has also been measured in nanodiamond encapsulated in optimised silicon nitride (SiNx) [4]. However, challenges remain to interface diamond with photonics in a scalable and manufacturable process. In particular, the need to identify and manipulate stochastically located emitters requires precise and time-intensive confocal microscopy.
Optically addressable solid-state spin defects have emerged as powerful multimodal quantum sensors, with nitrogen-vacancy (NV) centers in bulk diamond providing benchmark quantum control and sensitivity under ambient conditions. Embedding such defects in nanodiamonds (NDs) extends these capabilities to mobile probes capable of accessing complex biological and nanoscale environments. Reduced dimensions, however, introduce constraints beyond volumetric spin impurities, notably enhanced lattice strain and surface-induced noise sources, which shorten NV spin relaxation times (T1 and T2) and destabilize the NV charge state, as well as resulting in pronounced particle-to-particle variability in NDs typically produced by top-down approaches. These effects complicate both sensing performance and the quantitative interpretation of multimodal signals in realistic environments. This article provides a structured perspective on the physical mechanisms by which material properties constrain NV behavior in NDs, together with mitigation strategies that shape the robust use of these mobile quantum sensors for biosensing and nanoscale science.
Quantum sensors encompass a diverse class of devices that exploit quantum coherence to detect weak or nanoscale signals. As their behavior is tied to physical constants, quantum sensors can achieve accuracy, repeatability, and precision approaching fundamental limits [1, 2]. As a result, these sensors have shown utility in a wide range of applications in both science and engineering leading to innovations. Among many solid-state spin systems, nitrogen-vacancy (NV) centers in diamonds have attracted considerable attention as a leading platform in many fields of quantum technologies, from quantum sensing to information processing and communication applications. They have superior physical properties, and their quantum coherence is preserved even at room temperature. The energy levels of NV centers are sensitive to magnetic fields, electric fields, strain, and temperature, and the spatial resolution is scalable from nanometers to millimeters. Therefore, diamond quantum sensors are distinctive sensors with multimodality and span scalable application fields. To realize an ideal quantum sensor for applications, the technical challenges in the sensor materials and the quantum control techniques, such as coherent microwave spin manipulation, effective optical spin-state initialization, and readout, have been developed. This chapter briefly explains the sensing principle using NV centers and then introduces sensor systems for biomedical applications, and monitoring of batteries for electric vehicles and internal power devices.