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Devices for Integrated Circuit (DevIC)

Homomorphic Encryption in Quantum Computing

Surojit Mondal, Bikash Debnath, Jadav Chandra Das, Debashis De

Published Apr 5, 2025• 0 citations
Publisher

Abstract

Homomorphic encryption (HE) is a groundbreaking cryptographic method that allows calculations on encrypted data without the need for decryption, thus safeguarding privacy and security. This article investigates how to implement homomorphic encryption with QISKIT, a free-to-use quantum computing framework. The research investigates the theoretical underpinnings of HE, its use in quantum computing, and its importance for privacy-preserving calculations. Moreover, the study covers adder circuits based on quantum logic gates, their realization with QISKIT, and the prospects for improving computational security in cloud environments. The results stress the practical viability of HE in quantum environments, underscoring its possible uses in secure data processing and privacy-enhancing technologies.

DOI
10.1109/devic63749.2025.11012553

Related papers

A Comparative Framework for Post-Quantum Cryptography and Homomorphic Encryption: Integration, Methodologies, and Applications

Dr Rajendirakumar S

Abstract The rapid evolution of quantum computing fundamentally threatens modern cryptographic infrastructures, necessitating a paradigm shift toward advanced encryption techniques. While post-quantum cryptography (PQC) ensures that data remains secure against quantum algorithmic decryption, it does not inherently facilitate the processing of that data in untrusted environments. Homomorphic encryption (HE) addresses this computational privacy requirement, yet traditional HE schemes rely on classical mathematical problems that are easily compromised by quantum systems. This paper presents a comprehensive comparative framework that integrates post-quantum cryptographic principles with homomorphic capabilities to enable quantum-resistant, privacy-preserving computation. By analyzing lattice-based algorithms, code-based cryptography, and hardware acceleration paradigms, this study maps the existing trade-offs between security, computational overhead, and practical deployment feasibility in the impending quantum era. Keywords: PQC, HE. 1.Introduction The rapid evolution of quantum computing technology presents a profound threat to modern cryptographic infrastructures. As quantum algorithms, notably Shor's algorithm, mature, they acquire the capability to solve nondeterministic polynomial time problems in polynomial time, thereby breaking traditional asymmetric encryption standards such as RSA and Elliptic Curve Cryptography (ECC) (Chen, 2024). Consequently, the development of post-quantum cryptography (PQC) has become a global imperative to secure sensitive communications and data against future quantum adversaries (Pranjal & Chaturvedi, 2024). Cryptographers are currently focusing on transitioning secure systems to these newly established PQC standards before large-scale quantum computers become commercially viable. While PQC addresses the secure transmission and storage of data, it does not inherently solve the problem of secure data processing in untrusted cloud environments. Homomorphic encryption (HE) provides a sophisticated mechanism that allows computations to be performed directly on encrypted data without requiring prior decryption (Jain & Cherukuri, 2023). The core problem addressed in this paper is the conceptual and practical integration of PQC with HE shown in Fig1.1 which is essential for ensuring quantum-safe, privacy-preserving computation in distributed architectures. Achieving this synthesis is highly complex due to the massive computational overhead and noise accumulation inherent to both cryptographic domains. However, existing approaches to privacy-preserving computation remain broadly insufficient for the post-quantum era. First, conventional homomorphic encryption schemes rely heavily on mathematical hardness assumptions, such as integer factorization or discrete logarithms, which are demonstrably vulnerable to quantum attacks (Chen, 2024). Second, while some high-performance fully homomorphic implementations exist, they suffer from prohibitive computational overhead and severe ciphertext expansion, making widespread deployment impractical without specialized mitigation strategies (Tseng et al., 2025). Third, hardware-accelerated privacy solutions often rely on trusted execution environments, like Intel SGX, which inherently introduce side-channel vulnerabilities and force reliance on centralized hardware trust rather than pure mathematical security (Sadat et al., 2017). To overcome these critical limitations, this paper proposes a structured comparative methodology for evaluating quantum-resistant homomorphic encryption systems. Specifically, our paper makes the following main contributions: We provide a comprehensive comparative framework that categorizes and evaluates lattice-based and code-based homomorphic encryption schemes against classical performance constraints. We propose a structured, hypothetical evaluation pipeline designed to benchmark the computational overhead and latency of post-quantum homomorphic algorithms in federated networking environments. 2.Privacy-preserving computation The literature surrounding privacy-preserving computation can be broadly classified into three primary categories, the first being classical and fully homomorphic encryption (FHE) systems. The core idea behind these schemes is the preservation of algebraic structures during encryption, allowing operations on ciphertexts to reflect directly on the underlying plaintexts without exposing the raw data (Jain & Cherukuri, 2023). A major strength of these classical FHE systems, such as those utilized in encrypted relational databases like FHE-SQL, is their ability to provide end-to-end cryptographic protection for queries without relying on trusted hardware modules (Tseng et al., 2025). However, a fundamental weakness is that early FHE models, and their underlying privacy homomorphisms, remain fundamentally susceptible to quantum cryptanalysis due to their reliance on classical mathematical problems (Sen, 2013). Compared to these classical paradigms, our work specifically focuses on migrating these operational homomorphic properties into genuinely quantum-safe mathematical frameworks. The second category of related work focuses on hardware acceleration and hybrid computational environments for homomorphic encryption. The core idea here involves leveraging specialized hardware, such as ASIC AI chips or coarse-grained compute architectures like Google's TPUs, to mitigate the enormous computational overhead associated with HE (Tong et al., 2025). The strength of this approach lies in its ability to bridge the energy-efficiency gap, often utilizing intelligent compiler frameworks to convert high-precision modular arithmetic into dense, low-precision matrix multiplications. Conversely, the weakness of hardware-centric methods is that architectural mismatches frequently lead to severe resource under-utilization, and hybrid solutions utilizing components like Intel SGX introduce hardware trust assumptions that can compromise pure cryptographic integrity (Sadat et al., 2017). Unlike these approaches, our framework prioritizes algorithmic resilience and quantum resistance over purely hardware-driven and enclave-based optimizations. The third category encompasses emerging post-quantum and quantum homomorphic paradigms, which seek to unify quantum resistance with computational privacy. Researchers have proposed lattice-based HE schemes to replace vulnerable legacy systems like Paillier and ElGamal, successfully enabling secure applications such as federated learning (Chen, 2024). Similarly, code-based cryptography utilizing McEliece and non-negative matrix factorization has shown promise in providing faster encryption and decryption times while remaining mathematically secure against quantum computers (Chen, 2024). Furthermore, advanced quantum homomorphic encryption protocols have explored information-theoretic security combined with homomorphic quantum error-correction to ensure future-proof data protection (Ouyang & Rohde, 2022). While these systems represent the state-of-the-art, their primary weakness remains the massive memory and communication overhead introduced during distributed training protocols, which negatively impacts classification performance. Our approach builds upon this category by proposing a standardized methodology to systematically compare these disparate post-quantum homomorphic techniques. 3.Multi-stage Method To systematically evaluate and deploy post-quantum homomorphic encryption, we propose a structured, multi-stage methodological framework. The first step involves cryptographic primitive selection, where system architects must evaluate and choose between lattice-based constructs, such as ML-KEM adaptations, and code-based systems like McEliece, depending on their domain constraints (Chen, 2024). The second step requires the implementation of an algorithmic parameter optimization module, which dynamically adjusts polynomial degrees and error distributions to balance security levels with the operational multiplicative depth required by the application. Finally, the third step comprises the integration of a specialized abstraction layer designed to map complex high-precision cryptographic operations into hardware-friendly matrix operations, thereby reducing the inherent bottleneck of ciphertext evaluation. The key design choices within this framework are driven by the absolute necessity to balance quantum resistance with practical algorithmic utility. We prioritize lattice-based cryptography for our primary evaluation pathway because of its established resilience against quantum threats and its recent standardization by the National Institute of Standards and Technology (NIST) (Chen, 2024). Additionally, we explicitly design our framework to avoid reliance on trusted hardware environments, opting instead for pure cryptographic guarantees to prevent the side-channel data leaks that often plague hardware-enclave solutions. By focusing on algorithmic alignment and basis-aligned mathematical transformations, the framework ensures that homomorphic workloads can be optimized effectively without compromising the underlying post-quantum security proofs. To validate the efficacy of the proposed framework, we outline a comprehensive evaluation plan utilizing a hypothetical, high-dimensional healthcare benchmarking dataset. The experimental setup will simulate a secure genome-wide association study (GWAS) executing within a fully decentralized federated learning environment (Sadat et al., 2017). The primary metrics for this hypothetical evaluation will include key generation latency, ciphertext expansion ratio, and the amortized computational time required for homomorphic multiplication operations across distributed nodes. By systematically varying the cryptographic noise parameters and observing the resulting degradation in analytical performance, we aim to empirically map the trad

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The rise of quantum computing/technology potentially introduces significant security challenges to cloud computing, necessitating quantum-resistant encryption strategies as well as protection schemes and methods for cloud infrastructures offering quantum computing time and services (i.e. quantum clouds). This research explores various options for securing quantum clouds and ensuring privacy, especially focussing on the integration of homomorphic encryption (HE) into Eclipse Qrisp, a high-level quantum computing framework, to enhance the security of quantum cloud platforms. The study addresses the technical feasibility of integrating HE with Qrisp, evaluates performance trade-offs, and assesses the potential impact on future quantum cloud architectures. The successful implementation and Qrisp integration of three post-quantum cryptographic (PQC) algorithms demonstrates the feasibility of integrating HE with quantum computing frameworks. The findings indicate that while the Quantum One-Time Pad (QOTP) offers simplicity and low overhead, other algorithms like Chen and Gentry-Sahai-Waters (GSW) present performance trade-offs in terms of runtime and memory consumption. The study results in an overall set of recommendations for securing quantum clouds, e.g. implementing HE at data storage and processing levels, developing Quantum Key Distribution (QKD), and enforcing stringent access control and authentication mechanisms as well as participating in PQC standardization efforts.

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Homomorphic encryption experiments on IBM’s cloud quantum computing platform

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Quantum computing has undergone rapid development in recent years. Owing to limitations on scalability, personal quantum computers still seem slightly unrealistic in the near future. The first practical quantum computer for ordinary users is likely to be on the cloud. However, the adoption of cloud computing is possible only if security is ensured. Homomorphic encryption is a cryptographic protocol that allows computation to be performed on encrypted data without decrypting them, so it is well suited to cloud computing. Here, we first applied homomorphic encryption on IBM’s cloud quantum computer platform. In our experiments, we successfully implemented a quantum algorithm for linear equations while protecting our privacy. This demonstration opens a feasible path to the next stage of development of cloud quantum information technology.

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Cloud computing allows clients with limited computational resources to offload computations to more powerful remote servers. In this paradigm, homomorphic encryption (HE) schemes enable a server to run any computation on a client's encrypted data. These schemes are widely used in cloud computing protocols such as delegated computing, two-party secure computation, and zero-knowledge proofs. Quantum homomorphic encryption (QHE) aims to achieve the objectives of HE with quantum data and quantum circuits, enabling cloud quantum servers to compute on encrypted quantum data uploaded by clients. In this work, we consider a scenario where a client has access to a quantum “encryption/decryption device”, which allows the encryption, transmission, reception, and decryption of quantum states, but not universal quantum computation. In this setting, we provide a proof-of-concept software simulation of quantum homomorphic encryption. Our code implements the “EPR scheme” of Broadbent and Jeffery, which allows for the execution of universal quantum circuits by the server at the cost of requiring shared EPR pairs between the client and server. Our implementation explores the near-term viability of the EPR scheme. Perhaps unsurprisingly, our experiments indicate that the additional cost of homomorphic circuit evaluation is minor in comparison to the simulation cost of the quantum operations. Our simulation toolkit is implemented in Python and is open-source.

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This chapter presents a novel approach to securing sensitive healthcare data using quantum homomorphic encryption (QHE) integrated with the RSA encryption scheme. In an era where privacy-preserving data analysis is critical, particularly in healthcare, this method demonstrates how encrypted medical datasets, specifically the Diabetes dataset, can undergo computations such as homomorphic addition without compromising confidentiality. The chapter simulates encryption, quantum circuit-based homomorphic operations, and decryption using classical and quantum paradigms. It compares computational accuracy and efficiency between quantum and classical homomorphic models, establishing the feasibility of QHE for real-world medical applications. Performance is evaluated across multiple input sizes, demonstrating secure computation scalability. The results show that QHE offers promising capabilities for privacy-preserving analytics in healthcare and other sensitive domains, bridging quantum and classical cryptographic methods to support secure, efficient, and scalable data processing.

CRC Press eBooks•Nov 28, 2025•0 citations
Homomorphic encryption (HE) is a groundbreaking cryptographic method that allows calculations on encrypted data without the need for decryption, thus safeguarding privacy and security. This article investigates how to implement homomorphic encryption with QISKIT, a free-to-use quantum computing framework. The research investigates the theoretical underpinnings of HE, its use in quantum computing, and its importance for privacy-preserving calculations. Moreover, the study covers adder circuits based on quantum logic gates, their realization with QISKIT, and the prospects for improving computational security in cloud environments. The results stress the practical viability of HE in quantum environments, underscoring its possible uses in secure data processing and privacy-enhancing technologies.
Abstract The rapid evolution of quantum computing fundamentally threatens modern cryptographic infrastructures, necessitating a paradigm shift toward advanced encryption techniques. While post-quantum cryptography (PQC) ensures that data remains secure against quantum algorithmic decryption, it does not inherently facilitate the processing of that data in untrusted environments. Homomorphic encryption (HE) addresses this computational privacy requirement, yet traditional HE schemes rely on classical mathematical problems that are easily compromised by quantum systems. This paper presents a comprehensive comparative framework that integrates post-quantum cryptographic principles with homomorphic capabilities to enable quantum-resistant, privacy-preserving computation. By analyzing lattice-based algorithms, code-based cryptography, and hardware acceleration paradigms, this study maps the existing trade-offs between security, computational overhead, and practical deployment feasibility in the impending quantum era. Keywords: PQC, HE. 1.Introduction The rapid evolution of quantum computing technology presents a profound threat to modern cryptographic infrastructures. As quantum algorithms, notably Shor's algorithm, mature, they acquire the capability to solve nondeterministic polynomial time problems in polynomial time, thereby breaking traditional asymmetric encryption standards such as RSA and Elliptic Curve Cryptography (ECC) (Chen, 2024). Consequently, the development of post-quantum cryptography (PQC) has become a global imperative to secure sensitive communications and data against future quantum adversaries (Pranjal & Chaturvedi, 2024). Cryptographers are currently focusing on transitioning secure systems to these newly established PQC standards before large-scale quantum computers become commercially viable. While PQC addresses the secure transmission and storage of data, it does not inherently solve the problem of secure data processing in untrusted cloud environments. Homomorphic encryption (HE) provides a sophisticated mechanism that allows computations to be performed directly on encrypted data without requiring prior decryption (Jain & Cherukuri, 2023). The core problem addressed in this paper is the conceptual and practical integration of PQC with HE shown in Fig1.1 which is essential for ensuring quantum-safe, privacy-preserving computation in distributed architectures. Achieving this synthesis is highly complex due to the massive computational overhead and noise accumulation inherent to both cryptographic domains. However, existing approaches to privacy-preserving computation remain broadly insufficient for the post-quantum era. First, conventional homomorphic encryption schemes rely heavily on mathematical hardness assumptions, such as integer factorization or discrete logarithms, which are demonstrably vulnerable to quantum attacks (Chen, 2024). Second, while some high-performance fully homomorphic implementations exist, they suffer from prohibitive computational overhead and severe ciphertext expansion, making widespread deployment impractical without specialized mitigation strategies (Tseng et al., 2025). Third, hardware-accelerated privacy solutions often rely on trusted execution environments, like Intel SGX, which inherently introduce side-channel vulnerabilities and force reliance on centralized hardware trust rather than pure mathematical security (Sadat et al., 2017). To overcome these critical limitations, this paper proposes a structured comparative methodology for evaluating quantum-resistant homomorphic encryption systems. Specifically, our paper makes the following main contributions: We provide a comprehensive comparative framework that categorizes and evaluates lattice-based and code-based homomorphic encryption schemes against classical performance constraints. We propose a structured, hypothetical evaluation pipeline designed to benchmark the computational overhead and latency of post-quantum homomorphic algorithms in federated networking environments. 2.Privacy-preserving computation The literature surrounding privacy-preserving computation can be broadly classified into three primary categories, the first being classical and fully homomorphic encryption (FHE) systems. The core idea behind these schemes is the preservation of algebraic structures during encryption, allowing operations on ciphertexts to reflect directly on the underlying plaintexts without exposing the raw data (Jain & Cherukuri, 2023). A major strength of these classical FHE systems, such as those utilized in encrypted relational databases like FHE-SQL, is their ability to provide end-to-end cryptographic protection for queries without relying on trusted hardware modules (Tseng et al., 2025). However, a fundamental weakness is that early FHE models, and their underlying privacy homomorphisms, remain fundamentally susceptible to quantum cryptanalysis due to their reliance on classical mathematical problems (Sen, 2013). Compared to these classical paradigms, our work specifically focuses on migrating these operational homomorphic properties into genuinely quantum-safe mathematical frameworks. The second category of related work focuses on hardware acceleration and hybrid computational environments for homomorphic encryption. The core idea here involves leveraging specialized hardware, such as ASIC AI chips or coarse-grained compute architectures like Google's TPUs, to mitigate the enormous computational overhead associated with HE (Tong et al., 2025). The strength of this approach lies in its ability to bridge the energy-efficiency gap, often utilizing intelligent compiler frameworks to convert high-precision modular arithmetic into dense, low-precision matrix multiplications. Conversely, the weakness of hardware-centric methods is that architectural mismatches frequently lead to severe resource under-utilization, and hybrid solutions utilizing components like Intel SGX introduce hardware trust assumptions that can compromise pure cryptographic integrity (Sadat et al., 2017). Unlike these approaches, our framework prioritizes algorithmic resilience and quantum resistance over purely hardware-driven and enclave-based optimizations. The third category encompasses emerging post-quantum and quantum homomorphic paradigms, which seek to unify quantum resistance with computational privacy. Researchers have proposed lattice-based HE schemes to replace vulnerable legacy systems like Paillier and ElGamal, successfully enabling secure applications such as federated learning (Chen, 2024). Similarly, code-based cryptography utilizing McEliece and non-negative matrix factorization has shown promise in providing faster encryption and decryption times while remaining mathematically secure against quantum computers (Chen, 2024). Furthermore, advanced quantum homomorphic encryption protocols have explored information-theoretic security combined with homomorphic quantum error-correction to ensure future-proof data protection (Ouyang & Rohde, 2022). While these systems represent the state-of-the-art, their primary weakness remains the massive memory and communication overhead introduced during distributed training protocols, which negatively impacts classification performance. Our approach builds upon this category by proposing a standardized methodology to systematically compare these disparate post-quantum homomorphic techniques. 3.Multi-stage Method To systematically evaluate and deploy post-quantum homomorphic encryption, we propose a structured, multi-stage methodological framework. The first step involves cryptographic primitive selection, where system architects must evaluate and choose between lattice-based constructs, such as ML-KEM adaptations, and code-based systems like McEliece, depending on their domain constraints (Chen, 2024). The second step requires the implementation of an algorithmic parameter optimization module, which dynamically adjusts polynomial degrees and error distributions to balance security levels with the operational multiplicative depth required by the application. Finally, the third step comprises the integration of a specialized abstraction layer designed to map complex high-precision cryptographic operations into hardware-friendly matrix operations, thereby reducing the inherent bottleneck of ciphertext evaluation. The key design choices within this framework are driven by the absolute necessity to balance quantum resistance with practical algorithmic utility. We prioritize lattice-based cryptography for our primary evaluation pathway because of its established resilience against quantum threats and its recent standardization by the National Institute of Standards and Technology (NIST) (Chen, 2024). Additionally, we explicitly design our framework to avoid reliance on trusted hardware environments, opting instead for pure cryptographic guarantees to prevent the side-channel data leaks that often plague hardware-enclave solutions. By focusing on algorithmic alignment and basis-aligned mathematical transformations, the framework ensures that homomorphic workloads can be optimized effectively without compromising the underlying post-quantum security proofs. To validate the efficacy of the proposed framework, we outline a comprehensive evaluation plan utilizing a hypothetical, high-dimensional healthcare benchmarking dataset. The experimental setup will simulate a secure genome-wide association study (GWAS) executing within a fully decentralized federated learning environment (Sadat et al., 2017). The primary metrics for this hypothetical evaluation will include key generation latency, ciphertext expansion ratio, and the amortized computational time required for homomorphic multiplication operations across distributed nodes. By systematically varying the cryptographic noise parameters and observing the resulting degradation in analytical performance, we aim to empirically map the trad
The rise of quantum computing/technology potentially introduces significant security challenges to cloud computing, necessitating quantum-resistant encryption strategies as well as protection schemes and methods for cloud infrastructures offering quantum computing time and services (i.e. quantum clouds). This research explores various options for securing quantum clouds and ensuring privacy, especially focussing on the integration of homomorphic encryption (HE) into Eclipse Qrisp, a high-level quantum computing framework, to enhance the security of quantum cloud platforms. The study addresses the technical feasibility of integrating HE with Qrisp, evaluates performance trade-offs, and assesses the potential impact on future quantum cloud architectures. The successful implementation and Qrisp integration of three post-quantum cryptographic (PQC) algorithms demonstrates the feasibility of integrating HE with quantum computing frameworks. The findings indicate that while the Quantum One-Time Pad (QOTP) offers simplicity and low overhead, other algorithms like Chen and Gentry-Sahai-Waters (GSW) present performance trade-offs in terms of runtime and memory consumption. The study results in an overall set of recommendations for securing quantum clouds, e.g. implementing HE at data storage and processing levels, developing Quantum Key Distribution (QKD), and enforcing stringent access control and authentication mechanisms as well as participating in PQC standardization efforts.
Quantum computing has undergone rapid development in recent years. Owing to limitations on scalability, personal quantum computers still seem slightly unrealistic in the near future. The first practical quantum computer for ordinary users is likely to be on the cloud. However, the adoption of cloud computing is possible only if security is ensured. Homomorphic encryption is a cryptographic protocol that allows computation to be performed on encrypted data without decrypting them, so it is well suited to cloud computing. Here, we first applied homomorphic encryption on IBM’s cloud quantum computer platform. In our experiments, we successfully implemented a quantum algorithm for linear equations while protecting our privacy. This demonstration opens a feasible path to the next stage of development of cloud quantum information technology.
Growing interest in the field of quantum computing is fueled by quantum computers projected ”quantum supremacy” in speed and security. The potential for ultra-high speeds may produce a dramatic change in data science, machine learning, analytics, and information processing. This research study will focus on encryption algorithms where quantum computing may affect protocols and deciphering codes. Specifically, homomorphic encryption (HE) enables mathematical operations to be performed on encrypted data without having to decrypt the data in the process. Quantum homomorphic encryption (QHE) enables quantum circuits to be performed on encrypted qubits. In this research experience for undergraduates (REU) study, we design quantum circuits to implement QHE on a quantum teleportation circuit. The teleportation algorithm is profiled in terms of performance and complexity and comparative results are provided for encoded versus unencoded circuits. This work serves as a building block for encrypting more complex quantum algorithms such as Quantum Neural Networks (QNN).
Cloud computing allows clients with limited computational resources to offload computations to more powerful remote servers. In this paradigm, homomorphic encryption (HE) schemes enable a server to run any computation on a client's encrypted data. These schemes are widely used in cloud computing protocols such as delegated computing, two-party secure computation, and zero-knowledge proofs. Quantum homomorphic encryption (QHE) aims to achieve the objectives of HE with quantum data and quantum circuits, enabling cloud quantum servers to compute on encrypted quantum data uploaded by clients. In this work, we consider a scenario where a client has access to a quantum “encryption/decryption device”, which allows the encryption, transmission, reception, and decryption of quantum states, but not universal quantum computation. In this setting, we provide a proof-of-concept software simulation of quantum homomorphic encryption. Our code implements the “EPR scheme” of Broadbent and Jeffery, which allows for the execution of universal quantum circuits by the server at the cost of requiring shared EPR pairs between the client and server. Our implementation explores the near-term viability of the EPR scheme. Perhaps unsurprisingly, our experiments indicate that the additional cost of homomorphic circuit evaluation is minor in comparison to the simulation cost of the quantum operations. Our simulation toolkit is implemented in Python and is open-source.
This chapter presents a novel approach to securing sensitive healthcare data using quantum homomorphic encryption (QHE) integrated with the RSA encryption scheme. In an era where privacy-preserving data analysis is critical, particularly in healthcare, this method demonstrates how encrypted medical datasets, specifically the Diabetes dataset, can undergo computations such as homomorphic addition without compromising confidentiality. The chapter simulates encryption, quantum circuit-based homomorphic operations, and decryption using classical and quantum paradigms. It compares computational accuracy and efficiency between quantum and classical homomorphic models, establishing the feasibility of QHE for real-world medical applications. Performance is evaluated across multiple input sizes, demonstrating secure computation scalability. The results show that QHE offers promising capabilities for privacy-preserving analytics in healthcare and other sensitive domains, bridging quantum and classical cryptographic methods to support secure, efficient, and scalable data processing.