Challenges
Datasets
Workspaces
Papers
Discussions
Leaderboard
Log inSign up
Challenges
Datasets
Workspaces
Papers
Discussions
Leaderboard
Blog
Job Board
Q3AS

© 2026 Aqora Quantum S.A.S.

TermsPrivacyLegal Notice

RESEARCH REVIEW International Journal of Multidisciplinary

Study on Machine Learning Application in Quantum Circuit Synthesis

Jyoti, Amitabh Wahi, S.B.L Tripathi

Published Apr 20, 2025• 0 citations
Publisher

Abstract

In this Research Paper we have highlighted about the Study on Machine Learning Application in Quantum Circuit Synthesis. Quantum circuit synthesis, a fundamental task in quantum computing, involves designing efficient circuits to execute quantum algorithms on quantum computers. Machine learning techniques have been increasingly applied to enhance this process. One key area where machine learning excels is in optimizing quantum circuits for specific tasks. Quantum circuit synthesis often involves a large search space of possible circuit configurations, making it computationally intensive to find optimal solutions. Machine learning algorithms, such as reinforcement learning or genetic algorithms, can efficiently navigate this search space to identify high-performing circuit configurations. These algorithms learn from past experiences and iteratively improve their performance, gradually converging towards optimal solutions. Machine learning can aid in automating the design process by predicting the performance of quantum circuits based on their characteristics. By analyzing large datasets of quantum circuits and their corresponding performance metrics, machine learning models can identify patterns and correlations, enabling the prediction of circuit performance without the need for exhaustive simulations. Additionally, machine learning techniques can assist in error mitigation in quantum circuits. Quantum computers are susceptible to various types of errors, which can degrade the performance of quantum algorithms. Machine learning algorithms can analyze error patterns and devise strategies to mitigate them, leading to more reliable quantum circuits.

DOI
10.31305/rrijm.2025.v10.n4.002

Related papers

Quantum Machine Learning for Optimizing Entanglement Distribution in Quantum Sensor Circuits

Laxmisha Ashok Attisara, Sathish Kumar

In the rapidly evolving field of quantum computing, optimizing quantum circuits for specific tasks is crucial for enhancing performance and efficiency. More recently, quantum sensing has become a distinct and rapidly growing branch of research within the area of quantum science and technology. The field is expected to provide new opportunities, especially regarding high sensitivity and precision. Entanglement is one of the key factors in achieving high sensitivity and measurement precision [3]. This paper presents a novel approach utilizing quantum machine learning techniques to optimize entanglement distribution in quantum sensor circuits. By leveraging reinforcement learning within a quantum environment, we aim to optimize the entanglement layout to maximize Quantum Fisher Information (QFI) and entanglement entropy, which are key indicators of a quantum system's sensitivity and coherence, while minimizing circuit depth and gate counts. Our implementation, based on Qiskit, integrates noise models and error mitigation strategies to simulate realistic quantum environments. The results demonstrate significant improvements in circuit performance and sensitivity, highlighting the potential of machine learning in quantum circuit optimization by measuring high QFI and entropy in the range of 0.84-1.0 with depth and gate count reduction by 20-86%.

arXiv:2508.21252•Aug 28, 2025•0 citations

Quantum Optimization for Machine Learning

Asha Sohal, Ramesh Kait, Asha Sohal

The convergence of machine learning (ML) and quantum computing is quickly becoming a game-changing new frontier in computational science. The most intriguing area of overlap may be quantum optimization, which seeks to reduce the exponentially increasing complexity and computational cost of ML algorithms. As they grow larger and more complicated, traditional optimization methods, particularly in high-dimensional and non-convex space, will inevitably hit performance limits. Quantum optimization is the whole new paradigm that leverages quantum mechanical effects like superposition, entanglement, and tunnelling to explore solution spaces more efficiently. The chapter outlines the theory, practice, and potential of hybrid quantum-classical optimization algorithms for machine learning. The most brilliant research direction in the current NISQ (noisy intermediate-scale quantum) era is mixed systems leveraging classical computing capability augmented by quantum capacity. In such designs, computationally intensive subroutines like optimization for global optima or escape from local minima are left to quantum processors and data preprocessing, iterative refinement, and model testing are performed by classical processors. We start by defining the fundamental principles of quantum computing and acquainting readers with the fundamentals like qubits, quantum gates, and quantum circuits. These are the building blocks for quantum algorithms, which hopefully can be utilized for optimization, for example, the QAOA (quantum approximate optimization algorithm), the VQE (variational quantum Eigensolver), and quantum annealing. They all build to optimize the problems in some way differently: QAOA through parameterized quantum circuits, VQE through approximations of ground states of the Hamiltonians, and quantum annealing through quantum evolution to low-energy solutions. We then form a loop between these quantum algorithms and regular machine learning tasks. Optimization impacts virtually all ML phases, from training neural networks, where one reduces loss functions; feature selection, where one aims to discover the most relevant subset of input variables; and hyperparameter optimization, which often involves expensive search procedures over extremely large combinatorial spaces. Quantum optimization techniques can therefore, in principle, accelerate such procedures through computational complexity reduction and enhancing solutions over challenging landscapes. Realistic simulations and case studies emphasize the degree to which hybrid quantum-classical algorithms have been employed in solving ML problems, that is, QSVMs, quantum-enhanced clustering, and quantum reinforcement learning. Despite their experimental nature, these applications already show encouraging results in terms of improved performance metrics as well as reduction in time-to-solution compared to classical-only solutions. Notwithstanding that, this new field is not bereft of real challenges. Quantum hardware suffers from hard limits on qubit fidelity, decoherence, and scalability in the current times. Furthermore, quantum circuit integration into broad ML pipelines requires novel architectures and software platforms. As a counter to those issues, this chapter surveys recent advances in quantum programming languages, simulators, and hybrid platforms like PennyLane, Qiskit, and TensorFlow Quantum. We conclude by looking to the future possibility that quantum optimization will revolutionize the machine learning landscape. As hardware improves and algorithmic complexity increases, the possibility of quantum-powered learning systems solving hard problems becomes increasingly accessible. From speeding up deep network training to enabling new types of unsupervised learning, quantum optimization holds the potential to recast computational tractability in machine learning. This chapter is an all-encompassing introduction and state-of-the-art work for students, researchers, and practitioners interested in using quantum optimization for practical ML applications. It sets the foundation for understanding how to pursue hybrid approaches (how they may be applied today in the real world and bracing oneself for disruption in the future).

Auerbach Publications eBooks•Feb 24, 2026•0 citations

Integration of Machine Learning with Quantum Computing: Compilation of Quantum Circuit for Efficacy on Noisy Intermediate-Scale Quantum Devices

M. Praba, Ahmad Abdelhafiz Ali Samhan, V. Samuthira Pandi +3 more

Hybridizing machine learning (ML) with quantum computing has become an attractive strategy to increase computational power on Noisy Intermediate Scale Quantum (NISQ) devices. Although these can be potentially quantum advantage devices, their qubit numbers and noise are bounded and there are challenges when it comes to practical quantum circuit realization. This work concentrates on the creation of optimized quantum circuits via ML-based strategies, to enhance the performance of the circuits, to reduce the error rate and to accommodate the particular noise profile of the hardware of NISQ devices. The resulting suboptimal mappings with little or no consideration of noise and hardware topology in traditional quantum compilers can ruin the fidelity of quantum algorithm. Leveraging machine learning, and specifically reinforcement and supervised learning methods, our method learns to optimize compilation strategy for specific quantum hardware architecture. The paper proposes a framework that uses machine learning models to predict qubit mappings, gate decompositions, and transpilation paths that minimize gate depth and error accumulation. We also investigate transfer learning methods for propagating the learned compilation strategies to novel NISQ machines. Such methods are empirically validated on both simulated and real quantum hardware backends, providing evidence of circuit depth, execution time and error reductions. The results show that ML-assisted compilation can achieve better success probabilities for benchmark quantum algorithms like VQE and QAOA than conventional compilers. Furthermore, the work examines the interpretability of ML models providing hardware-aware optimization recommendations and understanding the noise patterns and methods of error correction. Our work highlights the key role of ML for transferring between theoretical quantum algorithms and their practical NISQ implementations. This integration boosts the immediate applicability of existing quantum devices and provides a basis for adaptive and scalable likelihood-based compilation for the era of fault-tolerant quantum computation. Our results motivate further investigation of hybrid classical-quantum workflows, in which ML iteratively improves compilation in accordance with changing hardware noise and capabilities. By improving quantum circuit compilation onNISQ computers, this work is taking steps toward the realization of quantum advantage in application scenarios such as optimization, cryptography, and quantum simulation without needing to wait for fully fault-tolerant large-scale quantum computers.

Asian Conference on Innovation in Technology (ASIANCON)•Aug 22, 2025•1 citation

Machine learning and quantum computing

BORDONI, SIMONE

This thesis presents original contributions at the intersection of quantum computing and machine learning, investigating how these two fields can benefit from each other. The first part of the thesis presents two applications of machine learning techniques in quantum computing. The first contribution involves the use of artificial neural networks for the decoding of quantum error correction codes, resulting in faster decoding times while maintaining a high level of accuracy. The originality of this work lies in the application of explainable machine learning techniques to both improve the decoding performance and to provide insights into the decoding process. The second contribution introduces a novel technique based on reinforcement learning to characterize and simulate the noise affecting a quantum chip. This technique reduces the heuristic assumption on the noise model, making it more adaptable to the specific noise characteristics of the quantum device. In the second part of the thesis, we demonstrate, with two examples, how it is possible to implement machine learning algorithms on quantum devices by replacing artificial neural networks with parametrized quantum circuits. The first contribution in this section introduces a quantum anomaly detection algorithm, applied to the field of high-energy physics. This algorithm allows for the identification of anomalous patterns in quantum data, maintaining a level of accuracy comparable to classical algorithms. The novelty of this work lies in the first use of quantum circuits for the task of anomaly detection in a muon drift chamber trigger system, with possible future applications to quantum detector systems in high-energy physics experiments. The second contribution presents the quantum version of a generative diffusion model, able to sample quantum states from a well-defined distribution. This first implementation of a quantum diffusion model is not meant to outperform classical models, but rather to show potential advantages and limitations of these kinds of algorithms. The aim of the thesis is to show how quantum computing can benefit from machine learning, and how machine learning can be implemented on quantum devices, setting the stage for future advancements in both fields.

•Sep 25, 2025•0 citations

Machine Learning Algorithms in Quantum Computing: A Survey

Somayeh Bakhtiari Ramezani, Alexander Sommers, Harish Kumar Manchukonda +2 more

Machine Learning (ML) aims at designing models that learn from previous experience, without being explicitly formulated. Applications of machine learning are inexhaustible, including recognizing patterns, predicting future trends and making decisions, and they are capable of handling sizable quantities of multi-dimensional data in the form of large vectors and tensors. To perform these operations on classical computers, however, requires vast time and computational resources. Unlike the classical computers that rely on computations using binary bits, Quantum Computers (QC) benefit from qubits which can hold combinations of 0 and 1 at the same time via superposition and entanglement. This makes QCs powerful at handling and post processing large tensors, making them a prime target for implementing ML algorithms. While several models used for ML on QCs are based on concepts from their classical computing counterparts, utilization of the QC's potential has made them the superior of the two. This paper presents an overview of the current state of knowledge in application of ML on QC, and evaluates the speed up, and complexity advantages of using quantum machines.

International Joint Conference on Neural Networks (IJCNN)•Jul 1, 2020•122 citations

AI/ML-Driven Electronic Design Automation Framework for Quantum-Aware VLSI Circuit Synthesis and Optimization in High-Performance Computing Applications

Increased development of high-performance computing (HPC) has increased the pressure on new paradigms in VLSI circuit design, as device scaling is approaching scaling limits where quantum effects become important.Conventional electronic design automation (EDA) processes have difficulties in dealing with nonlinear interactions that occur when quantum tunnelling, leakage currents, and probabilistic switching are also present in the deeply scaled technology.To overcome them, this paper suggests an all-encompassing AI/ML-based EDA architecture, which incorporates quantum-aware modelling, predictive synthesis, and adaptive optimization of future HPC-oriented next-generation VLSI systems.The framework has incorporated machine learning (ML)-based parametric estimation, reinforcement learning (RL) on layout exploration, and physics-guided neural models: nonclassical effects in nanoscale transistors.Furthermore, the system uses generative learning algorithms to create multiobjective design trade-offs in terms of timing, power, area, and quantum reliability.The hybrid digital-quantum design flow is presented, allowing to easily interchange the classical EDA operations and quantum-inspired device tests.Nanometer-scale benchmark circuit confirmation of the efficiency of synthesis, accuracy of leakage prediction, and rate of convergence of optimization are shown to be much enhanced with respect to more traditional EDA pipelines.The given methodology puts the emphasis on the role of intelligent automation as the means of guiding the VLSI research toward the point of quantum-awareness as the key to ensuring reliability, scalability, and energy efficiency in an HPC system.

Journal of VLSI Circuits and Systems•May 1, 2025•0 citations
In this Research Paper we have highlighted about the Study on Machine Learning Application in Quantum Circuit Synthesis. Quantum circuit synthesis, a fundamental task in quantum computing, involves designing efficient circuits to execute quantum algorithms on quantum computers. Machine learning techniques have been increasingly applied to enhance this process. One key area where machine learning excels is in optimizing quantum circuits for specific tasks. Quantum circuit synthesis often involves a large search space of possible circuit configurations, making it computationally intensive to find optimal solutions. Machine learning algorithms, such as reinforcement learning or genetic algorithms, can efficiently navigate this search space to identify high-performing circuit configurations. These algorithms learn from past experiences and iteratively improve their performance, gradually converging towards optimal solutions. Machine learning can aid in automating the design process by predicting the performance of quantum circuits based on their characteristics. By analyzing large datasets of quantum circuits and their corresponding performance metrics, machine learning models can identify patterns and correlations, enabling the prediction of circuit performance without the need for exhaustive simulations. Additionally, machine learning techniques can assist in error mitigation in quantum circuits. Quantum computers are susceptible to various types of errors, which can degrade the performance of quantum algorithms. Machine learning algorithms can analyze error patterns and devise strategies to mitigate them, leading to more reliable quantum circuits.
In the rapidly evolving field of quantum computing, optimizing quantum circuits for specific tasks is crucial for enhancing performance and efficiency. More recently, quantum sensing has become a distinct and rapidly growing branch of research within the area of quantum science and technology. The field is expected to provide new opportunities, especially regarding high sensitivity and precision. Entanglement is one of the key factors in achieving high sensitivity and measurement precision [3]. This paper presents a novel approach utilizing quantum machine learning techniques to optimize entanglement distribution in quantum sensor circuits. By leveraging reinforcement learning within a quantum environment, we aim to optimize the entanglement layout to maximize Quantum Fisher Information (QFI) and entanglement entropy, which are key indicators of a quantum system's sensitivity and coherence, while minimizing circuit depth and gate counts. Our implementation, based on Qiskit, integrates noise models and error mitigation strategies to simulate realistic quantum environments. The results demonstrate significant improvements in circuit performance and sensitivity, highlighting the potential of machine learning in quantum circuit optimization by measuring high QFI and entropy in the range of 0.84-1.0 with depth and gate count reduction by 20-86%.
The convergence of machine learning (ML) and quantum computing is quickly becoming a game-changing new frontier in computational science. The most intriguing area of overlap may be quantum optimization, which seeks to reduce the exponentially increasing complexity and computational cost of ML algorithms. As they grow larger and more complicated, traditional optimization methods, particularly in high-dimensional and non-convex space, will inevitably hit performance limits. Quantum optimization is the whole new paradigm that leverages quantum mechanical effects like superposition, entanglement, and tunnelling to explore solution spaces more efficiently. The chapter outlines the theory, practice, and potential of hybrid quantum-classical optimization algorithms for machine learning. The most brilliant research direction in the current NISQ (noisy intermediate-scale quantum) era is mixed systems leveraging classical computing capability augmented by quantum capacity. In such designs, computationally intensive subroutines like optimization for global optima or escape from local minima are left to quantum processors and data preprocessing, iterative refinement, and model testing are performed by classical processors. We start by defining the fundamental principles of quantum computing and acquainting readers with the fundamentals like qubits, quantum gates, and quantum circuits. These are the building blocks for quantum algorithms, which hopefully can be utilized for optimization, for example, the QAOA (quantum approximate optimization algorithm), the VQE (variational quantum Eigensolver), and quantum annealing. They all build to optimize the problems in some way differently: QAOA through parameterized quantum circuits, VQE through approximations of ground states of the Hamiltonians, and quantum annealing through quantum evolution to low-energy solutions. We then form a loop between these quantum algorithms and regular machine learning tasks. Optimization impacts virtually all ML phases, from training neural networks, where one reduces loss functions; feature selection, where one aims to discover the most relevant subset of input variables; and hyperparameter optimization, which often involves expensive search procedures over extremely large combinatorial spaces. Quantum optimization techniques can therefore, in principle, accelerate such procedures through computational complexity reduction and enhancing solutions over challenging landscapes. Realistic simulations and case studies emphasize the degree to which hybrid quantum-classical algorithms have been employed in solving ML problems, that is, QSVMs, quantum-enhanced clustering, and quantum reinforcement learning. Despite their experimental nature, these applications already show encouraging results in terms of improved performance metrics as well as reduction in time-to-solution compared to classical-only solutions. Notwithstanding that, this new field is not bereft of real challenges. Quantum hardware suffers from hard limits on qubit fidelity, decoherence, and scalability in the current times. Furthermore, quantum circuit integration into broad ML pipelines requires novel architectures and software platforms. As a counter to those issues, this chapter surveys recent advances in quantum programming languages, simulators, and hybrid platforms like PennyLane, Qiskit, and TensorFlow Quantum. We conclude by looking to the future possibility that quantum optimization will revolutionize the machine learning landscape. As hardware improves and algorithmic complexity increases, the possibility of quantum-powered learning systems solving hard problems becomes increasingly accessible. From speeding up deep network training to enabling new types of unsupervised learning, quantum optimization holds the potential to recast computational tractability in machine learning. This chapter is an all-encompassing introduction and state-of-the-art work for students, researchers, and practitioners interested in using quantum optimization for practical ML applications. It sets the foundation for understanding how to pursue hybrid approaches (how they may be applied today in the real world and bracing oneself for disruption in the future).
Hybridizing machine learning (ML) with quantum computing has become an attractive strategy to increase computational power on Noisy Intermediate Scale Quantum (NISQ) devices. Although these can be potentially quantum advantage devices, their qubit numbers and noise are bounded and there are challenges when it comes to practical quantum circuit realization. This work concentrates on the creation of optimized quantum circuits via ML-based strategies, to enhance the performance of the circuits, to reduce the error rate and to accommodate the particular noise profile of the hardware of NISQ devices. The resulting suboptimal mappings with little or no consideration of noise and hardware topology in traditional quantum compilers can ruin the fidelity of quantum algorithm. Leveraging machine learning, and specifically reinforcement and supervised learning methods, our method learns to optimize compilation strategy for specific quantum hardware architecture. The paper proposes a framework that uses machine learning models to predict qubit mappings, gate decompositions, and transpilation paths that minimize gate depth and error accumulation. We also investigate transfer learning methods for propagating the learned compilation strategies to novel NISQ machines. Such methods are empirically validated on both simulated and real quantum hardware backends, providing evidence of circuit depth, execution time and error reductions. The results show that ML-assisted compilation can achieve better success probabilities for benchmark quantum algorithms like VQE and QAOA than conventional compilers. Furthermore, the work examines the interpretability of ML models providing hardware-aware optimization recommendations and understanding the noise patterns and methods of error correction. Our work highlights the key role of ML for transferring between theoretical quantum algorithms and their practical NISQ implementations. This integration boosts the immediate applicability of existing quantum devices and provides a basis for adaptive and scalable likelihood-based compilation for the era of fault-tolerant quantum computation. Our results motivate further investigation of hybrid classical-quantum workflows, in which ML iteratively improves compilation in accordance with changing hardware noise and capabilities. By improving quantum circuit compilation onNISQ computers, this work is taking steps toward the realization of quantum advantage in application scenarios such as optimization, cryptography, and quantum simulation without needing to wait for fully fault-tolerant large-scale quantum computers.
This thesis presents original contributions at the intersection of quantum computing and machine learning, investigating how these two fields can benefit from each other. The first part of the thesis presents two applications of machine learning techniques in quantum computing. The first contribution involves the use of artificial neural networks for the decoding of quantum error correction codes, resulting in faster decoding times while maintaining a high level of accuracy. The originality of this work lies in the application of explainable machine learning techniques to both improve the decoding performance and to provide insights into the decoding process. The second contribution introduces a novel technique based on reinforcement learning to characterize and simulate the noise affecting a quantum chip. This technique reduces the heuristic assumption on the noise model, making it more adaptable to the specific noise characteristics of the quantum device. In the second part of the thesis, we demonstrate, with two examples, how it is possible to implement machine learning algorithms on quantum devices by replacing artificial neural networks with parametrized quantum circuits. The first contribution in this section introduces a quantum anomaly detection algorithm, applied to the field of high-energy physics. This algorithm allows for the identification of anomalous patterns in quantum data, maintaining a level of accuracy comparable to classical algorithms. The novelty of this work lies in the first use of quantum circuits for the task of anomaly detection in a muon drift chamber trigger system, with possible future applications to quantum detector systems in high-energy physics experiments. The second contribution presents the quantum version of a generative diffusion model, able to sample quantum states from a well-defined distribution. This first implementation of a quantum diffusion model is not meant to outperform classical models, but rather to show potential advantages and limitations of these kinds of algorithms. The aim of the thesis is to show how quantum computing can benefit from machine learning, and how machine learning can be implemented on quantum devices, setting the stage for future advancements in both fields.
Machine Learning (ML) aims at designing models that learn from previous experience, without being explicitly formulated. Applications of machine learning are inexhaustible, including recognizing patterns, predicting future trends and making decisions, and they are capable of handling sizable quantities of multi-dimensional data in the form of large vectors and tensors. To perform these operations on classical computers, however, requires vast time and computational resources. Unlike the classical computers that rely on computations using binary bits, Quantum Computers (QC) benefit from qubits which can hold combinations of 0 and 1 at the same time via superposition and entanglement. This makes QCs powerful at handling and post processing large tensors, making them a prime target for implementing ML algorithms. While several models used for ML on QCs are based on concepts from their classical computing counterparts, utilization of the QC's potential has made them the superior of the two. This paper presents an overview of the current state of knowledge in application of ML on QC, and evaluates the speed up, and complexity advantages of using quantum machines.
Increased development of high-performance computing (HPC) has increased the pressure on new paradigms in VLSI circuit design, as device scaling is approaching scaling limits where quantum effects become important.Conventional electronic design automation (EDA) processes have difficulties in dealing with nonlinear interactions that occur when quantum tunnelling, leakage currents, and probabilistic switching are also present in the deeply scaled technology.To overcome them, this paper suggests an all-encompassing AI/ML-based EDA architecture, which incorporates quantum-aware modelling, predictive synthesis, and adaptive optimization of future HPC-oriented next-generation VLSI systems.The framework has incorporated machine learning (ML)-based parametric estimation, reinforcement learning (RL) on layout exploration, and physics-guided neural models: nonclassical effects in nanoscale transistors.Furthermore, the system uses generative learning algorithms to create multiobjective design trade-offs in terms of timing, power, area, and quantum reliability.The hybrid digital-quantum design flow is presented, allowing to easily interchange the classical EDA operations and quantum-inspired device tests.Nanometer-scale benchmark circuit confirmation of the efficiency of synthesis, accuracy of leakage prediction, and rate of convergence of optimization are shown to be much enhanced with respect to more traditional EDA pipelines.The given methodology puts the emphasis on the role of intelligent automation as the means of guiding the VLSI research toward the point of quantum-awareness as the key to ensuring reliability, scalability, and energy efficiency in an HPC system.