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npj Quantum Information

Quantum-enhanced imaging for characterizing anisotropic material

Mengyu Xie, Sujian Niu, Zhao-Qi-Zhi Han, Yin‐Hai Li, Renhui Chen, Xiao-Hua Wang, M. Gao, Li Chen, Yue-Wei Song, Zhi‐Yuan Zhou, Bao-Sen Shi

Published Apr 4, 2025• 9 citations
Publisher

Abstract

Polarimetric imaging, a technique that captures the invisible polarization-related properties of given materials, has broad applications from fundamental physics to advanced fields such as target recognition, stress detection, biomedical diagnosis and remote sensing. The introduction of quantum sources into classical imaging systems has demonstrated distinct advantages, yet few studies have explored their combination with polarimetric imaging. In this study, we present a quantum polarimetric imaging system that integrates polarization-entangled photon pairs into a polarizer-sample-compensator-analyzer-typed polarimeter. Our system visualizes the birefringence properties of a periodical-distributed anisotropic material under decreasing illumination levels and diverse disturbing light sources. Compared to the classical system, the quantum approach reveals the superior sensitivity and robustness in low-light conditions, particularly useful in biomedical studies where the low illumination and non-destructive detection are urgently needed. The study also highlights the nonlocality of entangled photons in birefringence measurement, indicating the potential of quantum polarimetric system in the remote sensing domain.

DOI
10.1038/s41534-025-01014-z

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Polarimetric imaging, a technique that captures the invisible polarization-related properties of given materials, has broad applications from fundamental physics to advanced fields such as target recognition, stress detection, biomedical diagnosis and remote sensing. The introduction of quantum sources into classical imaging systems has demonstrated distinct advantages, yet few studies have explored their combination with polarimetric imaging. In this study, we present a quantum polarimetric imaging system that integrates polarization-entangled photon pairs into a polarizer-sample-compensator-analyzer-typed polarimeter. Our system visualizes the birefringence properties of a periodical-distributed anisotropic material under decreasing illumination levels and diverse disturbing light sources. Compared to the classical system, the quantum approach reveals the superior sensitivity and robustness in low-light conditions, particularly useful in biomedical studies where the low illumination and non-destructive detection are urgently needed. The study also highlights the nonlocality of entangled photons in birefringence measurement, indicating the potential of quantum polarimetric system in the remote sensing domain.
Polarimetric imaging, a technique that captures the invisible polarization-related properties of given materials, has broad applications from fundamental physics to advanced fields such as target recognition, stress detection, biomedical diagnosis and remote sensing. The introduction of quantum sources into classical imaging systems has demonstrated distinct advantages, yet few studies have explored their combination with polarimetric imaging. In this study, we present a quantum polarimetric imaging system that integrates polarization-entangled photon pairs into a polarizer-sample-compensator-analyzer (PSRA)-type polarimeter. Our system visualizes the birefringence properties of a periodical-distributed anisotropic material under decreasing illumination levels and diverse disturbing light sources. Compared to the classical system, the quantum approach reveals the superior sensitivity and robustness in low-light conditions, particularly useful in biomedical studies where the low illumination and non-destructive detection are urgently needed. The study also highlights the nonlocality of entangled photons in birefringence measurement, indicating the potential of quantum polarimetric system in the remote sensing domain.
Abstract Quantum imaging is an advanced method for microscopy or investigating the optical properties of materials or bio-medical inspections with high accuracy, low noise, and extremely low photo-damage. In previous work, we proposed a quantum imaging technique, in which variations in polarization angle due to reflection or transmission at the sample enhance image contrast in the second-order autocorrelation function at zero delay g 2(0). However, the image resolution observed was not satisfactory. In this report, to improve the image quality, the parameters such as coincidence window was optimized to distinguish photon statistics effectively due to change in polarization angle and the objective lens was utilized to focus the entangled photon beams. These modifications enabled optical imaging by accurately detecting slight polarization variations in different media. Although this method is effective for various samples, it has certain limitations for samples that exhibit polarization disturbances, such as those involving photon scattering. Nevertheless, the proposed approach demonstrates superior imaging performance under noisy conditions and low illumination, offering promising possibilities for high-quality quantum imaging applications.
Developing advanced technologies for sensing and imaging biological samples is crucial for medical applications, making quantum-enhanced methods particularly valuable, as they promise significant benefits over classical techniques. An important aspect of biological imaging is the characterization of tissue, which often involves resolving complex structural information such as birefringence and diattenuation. These measures require polarization-sensitive sensing which remains largely unaddressed in quantum-imaging techniques with undetected light. However, the bicolor nature and supreme phase sensitivity of nonlinear interferometers make them particularly advantageous for biological sensing. Hence, we theoretically introduce controllable polarizations of the interrogating light in a quantum-imaging setup and show the potential of nonlinear interferometers to simultaneously sense birefringence and diattenuation with undetected light while discussing both the low- and high-gain regime.
With the advancement of non-classical light sources such as single-photon and entangled-photon sources, innovative microscopy based on quantum principles has been proposed for traditional microscopy. This paper introduces the experimental demonstration of a quantum polarization microscopic technique that incorporates a quantum-entangled photon source. Although the point that employs the variation in polarization angle due to reflection or transmission at the sample is similar to classical polarization microscopy, the method for constructing the image contrast is significantly different. The image contrast is constructed by the coincidence count of signal and idler photons. In the case that the coincidence count is recorded from both the signal and idler photons, the photon statistics resemble a thermal state, similar to the blackbody radiation, but with a significantly higher peak intensity in the second-order autocorrelation function at zero delay that is derived from the coincidence count, while, when the coincidence count is taken from either the signal or idler photon only, although the photon state exhibits a thermal state again, the photon statistics become more dispersive and result in a lower peak intensity of the autocorrelation function. These different thermal states can be switched by slightly changing the photon polarization, which is suddenly aroused within a narrow range of the analyzer angle. The autocorrelation function g2(0) at the thermal state exhibits a sensitivity that is three times higher compared to the classical coincidence count rate, and this concept can be effectively utilized to enhance the contrast of the image. One of the key achievements of our proposed method is ensuring a low power of illumination (in the order of Pico-joules) for constructing the image. In addition, the robustness without any precise setup is also favorable for practical use. This polarization microscopic technique can provide a superior imaging technique compared to the classical method, opening a new frontier for research in material sciences, biology, and other fields requiring high-resolution imaging.
Abstract A nonlocal quantum approach is presented to polarimetry, leveraging the phenomenon of entanglement in photon pairs to enhance the precision in sample property determination. By employing two distinct channels, one containing the sample of interest and the other serving as a reference, the conditions are explored under which the inherent correlation between entangled photons can increase measurement sensitivity. Specifically, the quantum Fisher information (QFI) is calculated and compare the accuracy and sensitivity for the cases of single sample channel versus two channel quantum state tomography measurements. The theoretical results are verified by experimental analysis. The theoretical and experimental framework demonstrates that the nonlocal strategy enables enhanced precision and accuracy in extracting information about sample characteristics more than the local measurements. Depending on the chosen estimators and noise channels present, theoretical and experimental results show that noise‐induced bias decreases the precision for the estimated parameter. Such a quantum‐enhanced nonlocal polarimetry holds promise for advancing diverse fields including material science, biomedical imaging, and remote sensing, via high‐precision measurements through quantum entanglement.
Quantum techniques can be used to enhance the signal-to-noise ratio in optical imaging. Leveraging the latest advances in single-photon avalanche diode array cameras and multiphoton detection techniques, here, we introduce a supersensitive phase imager, which uses space-polarization hyperentanglement to operate over a large field of view without the need of scanning operation. We show quantum-enhanced imaging of birefringent and nonbirefringent phase samples over large areas, with sensitivity improvements over equivalent classical measurements carried out with equal number of photons. The potential applicability is demonstrated by imaging a biomedical protein microarray sample. Our technology is inherently scalable to high-resolution images and represents an essential step toward practical quantum-enhanced imaging.