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Advances in computers

Quantum machine learning: Breaking classical boundaries for cancer identification in next-generation artificial intelligence

Ramendra Pratap Singh, Md. Sadruddin Ahmad, Vijayalakshmi Chintamaneni, Ch. Bhavani, Meenakshi Sharma, Bakshish Singh

Published Jan 1, 2025• 1 citation
Publisher
DOI
10.1016/bs.adcom.2025.02.003

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Quantum computing is rapidly advancing and offering new ways to improve artificial intelligence (AI). The most recent advancement is Quantum Machine Learning (QML), an exciting new field that involves the exploration of combining quantum computing principles with machine learning methods to solve complex problems that have high-dimensional problem-solving models that are impossible to address with classical models. The objective of this research was a descriptive-analytical examination of combining classical machine learning with quantum computing principles, specifically using Variational Quantum Classifiers (VQC) to train on a nonlinear XOR dataset, to assess the proposition of QML. The VQC was able to amongst quantum features, and learning how to classify using parameterized variational circuits to model nonlinear decision boundaries as models not achievable using classical linear classifiers. Training convergence was demonstrated with decreasing training and test losses, with the final model achieving test accuracy of nearly 0.85. The training curves and the decision boundary plots illustrated the model’s ability to learn the more complex decision boundaries. This study demonstrated QML's ability to coexist with classical machine learning studies with the ability to exploit quantum entanglement and quantum parallelism. This paper concluded that QML has great potential to challenge the concerns of next generation applications in finance, healthcare, and secure communications and to optimize computational power and scalability.
Background: Breast cancer diagnostic data is complex and accompanied by noise. Quantum machine learning can enhance the accuracy, efficiency, and scalability of artificial intelligence algorithms and has applications in various fields such as drug discovery and personalized medicine. Methods: In the systematic review conducted, the databases PubMed, Embase, Scopus, and Web of Science were searched in December 2024. The search strategy included the keywords "Breast Cancer," "Artificial Intelligence," and "Quantum machine learning" along with their synonyms in article titles. Descriptive, qualitative, review, and non-English studies were excluded. The qualitative evaluation of the articles and the assessment of their bias were determined based on the Joanna Briggs Institute (JBI) indicators checklist. Results: Twenty-nine studies utilizing artificial intelligence models for personalized breast cancer management were selected. Seventeen studies employing various deep learning methods achieved satisfactory results in predicting treatment response and prognosis, effectively contributing to the personalized management of breast cancer. Twenty-six studies demonstrated that machine learning methods could enhance the processes of classification, screening, diagnosis, and prognosis of breast cancer. The methods most frequently used in modeling were quantum support vector machine (QSVM), quantum convolutional neural network (QCNN), and quantum neural network (QNN), with an average AUC of 0.91. Additionally, the average accuracy, sensitivity, specificity, and precision indices of the models ranged from 90% to 96%. Conclusion: Quantum computing can address some challenges arising from the increasing complexity and size of artificial intelligence models. Overall, the combination of artificial intelligence and quantum computing can significantly accelerate the drug discovery process and the development of effective drugs.