Abstract The quantum-like paradigm has emerged over the last decade to describe non-linear, dynamical, complex phenomena using quantum mechanics as a tool. In essence, it takes advantage of the linearity of quantum information processing, allowing for complex correlations through entanglement. In a quantum- and neuroscience truly interdisciplinary research, we found that an open quantum spin network, mapping a neural system, can successfully simulate the human sense of number as a global dynamical property, in contrast with the poor performance of conventional Artificial Neural Networks. Here, we discuss how the simulation can be extended to other important complex perceptual phenomena like the perception of space, time, and numbers, known to be interdependent with each other, suggesting that a shared neuronal mechanism is operating in the brain. Here we present a research program that aims at creating a quantum toolbox to simulate this integrated space-time-number sensory ability of our brain, with open-quantum systems methods. We will explore the implications of more general quantum-matter paradigms, and their possible coding into a quantum technology.
Abstract The quantum-like paradigm has emerged over the last decade to describe non-linear, dynamical, complex phenomena using quantum mechanics as a tool. In essence, it takes advantage of the linearity of quantum information processing, allowing for complex correlations through entanglement. In a quantum- and neuroscience truly interdisciplinary research, we found that an open quantum spin network, mapping a neural system, can successfully simulate the human sense of number as a global dynamical property, in contrast with the poor performance of conventional Artificial Neural Networks. Here, we discuss how the simulation can be extended to other important complex perceptual phenomena like the perception of space, time, and numbers, known to be interdependent with each other, suggesting that a shared neuronal mechanism is operating in the brain. Here we present a research program that aims at creating a quantum toolbox to simulate this integrated space-time-number sensory ability of our brain, with open-quantum systems methods. We will explore the implications of more general quantum-matter paradigms, and their possible coding into a quantum technology.
This research investigates the potential of utilizing quantum entanglement to simulate information encoding and decoding mechanisms within biological neural networks. The core premise is that quantum phenomena, specifically entanglement, may play a more significant role in biological neuronal processing than previously acknowledged. This work proposes a novel approach employing quantum bits (qubits) to represent individual neurons, with connections between neurons established through quantum entanglement. The simulation aims to mimic the processes of synaptic transmission and signal propagation observed in biological neural networks. Mathematical formulations describe the evolution of the entangled qubit states under influence of simulated neuronal inputs, and the measurement processes are modeled to represent the observed output signals. This research offers a theoretical framework for exploring the interplay between quantum mechanics and biological neural systems, potentially leading to a deeper understanding of the fundamental principles governing brain function. The study utilizes a discrete-time simulation approach, allowing for a detailed analysis of the dynamics of the entangled neural network. Key performance indicators, such as the fidelity of information transfer and the robustness of the simulated network, are explored. The results suggest that quantum entanglement can provide a viable model for simulating complex neural processes, warranting further investigation into the potential for quantum computing to revolutionize our understanding of the brain.
Quantum neurobiology is concerned with potential quantum effects operating in the brain and the application of quantum information science to neuroscience problems, the latter of which is the main focus of the current paper. The human brain is fundamentally a multiscalar problem, with complex behavior spanning nine orders of magnitude-scale tiers from the atomic and cellular level to brain networks and the central nervous system. In this review, we discuss a new generation of bio-inspired quantum technologies in the emerging field of quantum neurobiology and present a novel physics-inspired theory of neural signaling (AdS/Brain (anti-de Sitter space)). Three tiers of quantum information science-directed neurobiology applications can be identified. First are those that interpret empirical data from neural imaging modalities (EEG, MRI, CT, PET scans), protein folding, and genomics with wavefunctions and quantum machine learning. Second are those that develop neural dynamics as a broad approach to quantum neurobiology, consisting of superpositioned data modeling evaluated with quantum probability, neural field theories, filamentary signaling, and quantum nanoscience. Third is neuroscience physics interpretations of foundational physics findings in the context of neurobiology. The benefit of this work is the possibility of an improved understanding of the resolution of neuropathologies such as Alzheimer’s disease.
This paper introduces the Quantum Mechanics Simulation of Neurons Model (QMNN), a novel approach to simulating neuronal behavior based on fundamental principles of quantum mechanics. Traditional artificial neural networks (ANNs) often struggle to accurately replicate the complex dynamics observed in biological neurons due to their reliance on classical computational methods. QMNN leverages concepts such as superposition and entanglement, key features of quantum mechanics, to represent neuronal states and interactions. The model employs a discrete quantum system, where neuronal activity is represented by quantum states, allowing for inherent parallelism and potentially capturing phenomena currently inaccessible to classical neural simulations. This work details the core concepts of QMNN, outlining its mathematical formulation, key components, and potential advantages over conventional ANN approaches. We present a simplified model of a single neuron utilizing a quantum bit (qubit) to represent its state. The model's equations reflect the Schrödinger equation and the evolution of quantum states under influence of external stimuli. The simulation explores scenarios demonstrating the potential for increased computational efficiency and the ability to model phenomena like quantum coherence within neuronal networks. Further research will focus on scaling the model to multi-neuron networks and investigating the model's applicability to various neurological conditions.
The tantalizing hypothesis that quantum phenomena underpin the brain’s remarkable computational abilities has sparked intense interdisciplinary interest. This study delves into quantum neuroscience by computationally exploring quantum coherence in neural systems, aiming to uncover whether quantum effects enhance information processing. We developed a sophisticated model simulating a 1,000-qubit neural network, with each qubit representing a neuron entangled under biologically relevant conditions (310 K, 0.15 µs coherence time). Using IBM’s Qiskit framework, we tested signal propagation efficiency, latency, and coherence duration across four conditions: quantum models with full, moderate, and high decoherence, and a classical benchmark. Our results reveal a striking 19.4% improvement in signal propagation efficiency in the full-coherence quantum model (95.8% ± 2.9%) compared to the classical model (76.4% ± 5.1%; p < 0.001). Latency was reduced by 31%, with the quantum model achieving 0.68 µs versus 0.98 µs for the classical model. Coherence persisted for up to 1.5 µs, sufficient for short-range neural signaling. Extensive sensitivity analyses, varying temperature (300–325 K), noise (0.01–0.12 µs^-1), and network size (500–1,500 qubits), confirmed robustness, with efficiency remaining above 90% under moderate perturbations. These findings suggest quantum coherence could complement classical neural mechanisms, potentially enhancing processes like sensory integration or consciousness. However, biological complexity, including biochemical interactions, warrants further exploration. We advocate for experimental validation using advanced quantum sensors, such as nitrogen-vacancy centers, to detect coherence in neural tissue. This study bridges quantum physics and neuroscience, offering a robust computational framework to probe the brain’s quantum potential and inspiring future interdisciplinary research into cognition’s mechanistic underpinnings.
Biological neuronal networks represent a fundamental component of complex systems, including the brain. Simulating these networks accurately and efficiently is a significant challenge, largely due to the intricate, non-linear interactions between neurons. Traditional simulation methods, often relying on numerical integration techniques like the Hodgkin-Huxley model, are computationally intensive, particularly when scaling to large networks. This paper proposes a novel approach to neuronal network simulation inspired by quantum mechanics, specifically leveraging concepts of superposition and entanglement. We introduce a framework that utilizes quantum-inspired algorithms to represent and evolve neuronal states, aiming to dramatically reduce computational overhead. The core idea involves mapping neuronal dynamics onto a quantum system, where neurons are represented by qubits, and synaptic connections are modeled as quantum gates. The simulation process then utilizes quantum algorithms to evolve the system, effectively capturing the parallel and interconnected nature of neuronal networks. We present a mathematical formulation of the simulation process, focusing on the evolution equation for neuronal states. We explore key concepts like wave function collapse and measurement in the context of neuronal network simulation, offering a potential pathway for more realistic and efficient modeling of biological neural systems. The ultimate goal is to provide a computationally tractable method for simulating large-scale neuronal networks, leading to improved understanding of brain function and potentially facilitating the development of advanced neurotechnologies. The presented framework offers a distinct alternative to conventional methods, promising significant advantages in terms of speed and scalability.
ABSTRACT Recent advances at the intersection of quantum physics, neuroscience, and cognitive science have renewed interest in whether quantum phenomena and quantum‐inspired formalisms can inform models of human cognition and decision‐making. While classical neural and computational models explain many aspects of perception and behavior, they face limitations in accounting for contextuality, order effects, probabilistic reasoning violations, ambiguity resolution, and rapid information integration. This review synthesizes evidence and theoretical frameworks linking quantum‐related principles to cognition, with emphasis on quantum sensing in biological systems, molecular and subcellular quantum‐relevant mechanisms, quantum‐to‐classical transition pathways, quantum‐inspired models of perception and decision‐making, and quantum‐inspired computational approaches. It also extends beyond the probabilistic arm of quantum cognition by considering emerging equilibrium‐based and causal‐logical theories, including mental equilibrium, brain‐universe similarity, mind‐light‐matter unity, quantum emergence, and quantum intelligence. Throughout, the review distinguishes physically instantiated quantum mechanisms from abstract quantum‐like formalisms that model contextuality, mental entanglement, and non‐separable cognitive dynamics without requiring sustained macroscopic quantum coherence in the brain. Finally, it identifies methodological challenges and future directions for advancing quantum cognitive science toward experimentally testable and biologically meaningful theories.