Recently, there has been growing interest in medical image analysis methods based on multi-layer perceptron (MLP), which have demonstrated remarkable performance in this field. Typically, the MLP has been employed to flatten feature maps along the channel and spatial dimensions and encode them to capture the overall feature information. However, for MLP-based architecture, the whole learning process requires high computational complexity, a large number of parameters, and large-scale training datasets. Meanwhile, quantum tensor network (QTN), derived from quantum many-body systems, have gained popularity in machine learning due to their ability to reduce the number of parameters and explore the correlation of remote elements in an image through a tensor contraction operation. In this paper, we propose a novel framework named QTN-MLP based on QTN and MLP to tackle the weaknesses of MLP. This paper has been extensively validated on the COVID-CT dataset and ISIC 2018 dataset, and the experiments show that our method competes with state-of-the-art methods with lower computational complexity and fewer parameters.
Recently, there has been growing interest in medical image analysis methods based on multi-layer perceptron (MLP), which have demonstrated remarkable performance in this field. Typically, the MLP has been employed to flatten feature maps along the channel and spatial dimensions and encode them to capture the overall feature information. However, for MLP-based architecture, the whole learning process requires high computational complexity, a large number of parameters, and large-scale training datasets. Meanwhile, quantum tensor network (QTN), derived from quantum many-body systems, have gained popularity in machine learning due to their ability to reduce the number of parameters and explore the correlation of remote elements in an image through a tensor contraction operation. In this paper, we propose a novel framework named QTN-MLP based on QTN and MLP to tackle the weaknesses of MLP. This paper has been extensively validated on the COVID-CT dataset and ISIC 2018 dataset, and the experiments show that our method competes with state-of-the-art methods with lower computational complexity and fewer parameters.
In the Quantum-Train (QT) framework, mapping quantum state measurements to classical neural network weights is a critical challenge that affects the scalability and efficiency of hybrid quantum-classical models. The traditional QT framework employs a multi-layer perceptron (MLP) for this task, but it struggles with scalability and interpretability. To address these issues, we propose replacing the MLP with a tensor network-based model and introducing a distributed circuit ansatz designed for large-scale quantum machine learning with multiple small quantum processing unit nodes. This approach enhances scalability, efficiently represents high-dimensional data, and maintains a compact model structure. Our enhanced QT framework retains the benefits of reduced parameter count and independence from quantum resources during inference. Experimental results on benchmark datasets demonstrate that the tensor network-based QT framework achieves competitive performance with improved efficiency and generalization, offering a practical solution for scalable hybrid quantum-classical machine learning.
Quantum Convolutional Neural Networks (QCNNs) have became a promising field for quantum advantage in feature extraction and classification of different datasets like Handwritten datasets, Fashion datasets, particularly useful for complex datasets like medical images. Medical image classification has emerged as a critical component in modern healthcare diagnostics, particularly for tumor detection and cancer diagnosis. Normally, Classical CNN is used for image classification but they may face certain challenges in achieving further improvements in accuracy, computational efficiency, processing time. Also, it becomes difficult to train for high-dimensional medical datasets and extracting complex feature representations. Therefore, In this proposal, Image classification through a Scalable and Resource efficient QCNN is proposed which integrates classical CNN with quantum computing. This review examines the current state of medical image classification for tumor detection, analyzes the transition from classical CNNs to quantum-based architectures, and explores the potential of QCNNs in revolutionizing medical diagnostics. This research includes QCNN architecture which will include selective feature encoding using encoding technique such as Z Feature map and quantum circuits for convolutional layers and pooling layers to handle multi-modal medical data (e.g., MRI and CT scans). We aim to achieve superior accuracy with reduced parameters over classical CNNs. This work advances quantum ML toward practical deployment in resource-limited healthcare settings.
Introduction: Medical image classification is a crucial task in cancer diagnosis, relying on the accurate analysis of high-dimensional imaging data. While Convolutional Neural Networks (CNNs) have shown great success in this domain, their performance is often limited by the shallow feature expressiveness and overfitting, particularly in small or heterogeneous datasets. Methods: Quantum machine learning offers new opportunities through high-dimensional representations and nonlinear transformations. In this work, we propose a Quantum-Enhanced Sandwich Convolutional Neural Network (QSCNN), a layered hybrid architecture that integrates quantum and classical modules. The model employs a quanvolutional layer for localized quantum feature extraction, followed by conventional convolution and pooling for hierarchical representation learning, and a variational quantum classifier for nonlinear decision-making. Results: QSCNN achieved higher accuracy and training stability than classical CNNs and QCCNN baselines across three medical imaging tasks.: brain tumor MRI, skin cancer dermoscopy, and lung cancer CT. Circuit depth analysis revealed a trade-off between expressiveness and robustness, and additional experiments with depolarizing noise confirmed the model’s resilience under realistic quantum error conditions. Discussion: This suggests that circuit design choices influence hybrid model behavior and generalization, supporting the feasibility of quantum-enhanced methods for small-sample medical imaging. However, the current evaluation is limited to relatively small benchmark datasets, and broader validation on large-scale data will be essential to confirm clinical applicability. Conclusion: In summary, QSCNN presents a feasible hybrid framework for enhancing medical image classification with quantum features. While preliminary, our results suggest potential advantages in accuracy and stability under NISQ conditions.
With the increasing adoption of machine learning tools like neural networks across several domains, interesting connections and comparisons to concepts from other domains are coming to light. In this work, we focus on the class of Tensor Networks, which has been a work horse for physicists in the last two decades to analyse quantum many-body systems. Building on the recent interest in tensor networks for machine learning, we extend the Matrix Product State tensor networks (which can be interpreted as linear classifiers operating in exponentially high dimensional spaces) to be useful in medical image analysis tasks. We focus on classification problems as a first step where we motivate the use of tensor networks and propose adaptions for 2D images using classical image domain concepts such as local orderlessness of images. With the proposed locally orderless tensor network model (LoTeNet), we show that tensor networks are capable of attaining performance that is comparable to state-of-the-art deep learning methods. We evaluate the model on two publicly available medical imaging datasets and show performance improvements with fewer model hyperparameters and lesser computational resources compared to relevant baseline methods.
Purpose This study investigates the integration of quantum-enhanced machine learning (QML) into medical image analysis, focusing on classification and feature extraction tasks. It aims to evaluate whether hybrid quantum-classical models can overcome the limitations of traditional machine learning in handling high-dimensional, clinically relevant imaging data. Design/methodology/approach Hybrid architectures combining classical preprocessing with quantum components, specifically variational quantum circuits (VQCs) and quantum kernel methods, were developed and implemented in simulated quantum environments using Qiskit and PennyLane on Google Colab. Publicly available datasets (ChestX-ray14, Brain Tumor MRI and CT Hemorrhage) were preprocessed and encoded into quantum states. Model performance was evaluated against classical baselines (MLP and CNN) using accuracy, precision, recall, F1-score, convergence speed and trainable parameters. Findings Quantum-enhanced models achieved competitive or superior performance compared to classical models with significantly fewer trainable parameters and faster convergence. The Quantum Kernel SVM demonstrated the highest precision (89.1%) and F1-score (88.5%) using only 8 parameters, while VQC models converged up to 2× faster than classical baselines. These results highlight the potential of QML to improve efficiency, robustness and scalability in diagnostic imaging workflows, particularly in resource-constrained or data-limited settings. Research limitations/implications The study relies on simulated quantum environments, which do not capture hardware noise or qubit limitations. Future work will extend to real quantum devices, multimodal data integration and interpretability strategies. Practical implications Quantum kernel methods and lightweight VQC architectures enable faster, resource-efficient diagnostic modeling, making them suitable for clinical environments with limited computational capacity or time-sensitive decision-making needs. Social implications Improving the efficiency and accessibility of medical image analysis has the potential to support faster diagnosis and enhance healthcare delivery, particularly in underserved or resource-limited regions. Originality/value This study provides a practical evaluation of hybrid quantum-classical models applied to multiple real medical imaging datasets in a reproducible simulated environment. It offers an early-stage framework demonstrating how QML techniques can be integrated into existing machine learning pipelines for medical image analysis.
Multilayer Perceptron (MLP) is a simple practice of Neural Network (NN) and the cornerstone of research and development of deep learning. Each neuron is connected to all neurons in the previous layer and implements a non-linear mapping through activation functions. MLP can learn complex non-linear relationships among features through the superposition of multiple hidden layers, but it still cannot discover the inherent strong correlation among features. The reason is that each neuron uses a simple weighted summation method to organize all the neurons in the previous layer. Inspired by quantum theory, this paper builds a non-linear NN layer that can mine strong correlations among features based on multi-body quantum systems, and then constructs a multi-layer perceptron, called Quantum-inspired MLP (QiMLP). It is conceivable that QiMLP will have important inspirational significance in reshaping machine learning, deep learning and large language models. We theoretically analyzed the basis for QiMLP to mine strong correlations among features, and implemented experiments on multiple classic deep learning datasets. Experimental results verify that QiMLP not only learns strong correlations among features, but also significantly reduces the number of parameters with hundreds of times improvement.