Moore's law has accurately predicted the growth of computing power from the increasing density of transistor devices on integrated circuit (IC) chips. Many believe this trend will continue indefinitely; however, quantum physics may define a future limit to electronic miniaturization and ever-increasing computing power. Heisenberg uncertainty in terms of the Compton wavelength of particle physics suggests such a boundary, even for anticipated advances in quantum computing. Moore's law has been a reliable predictor of the pace of electronic technology advancement; however, quantum physics may provide the ultimate limit to this mathematical model.