In the present paper, we develop a general mathematical framework for discrimination between
r≥2 quantum states by
N≥1 sequential receivers for the case in which every receiver obtains a conclusive result. This type of discrimination constitutes an
N -sequential extension of the minimum-error discrimination by one receiver. The developed general framework, which is valid for a conclusive discrimination between any number
r≥2 of quantum states, pure or mixed, of an arbitrary dimension and any number
N≥1 of sequential receivers, is based on the notion of a quantum state instrument, and this allows us to derive new important general results. In particular, we find a general condition on
r≥2 quantum states under which, within the strategy in which all types of receivers’ quantum measurements are allowed, the optimal success probability of the
N -sequential conclusive discrimination between these
r≥2 states is equal to that of the first receiver for any number
N≥2 of further sequential receivers and specify the corresponding optimal protocol. Furthermore, we extend our general framework to include an
N -sequential conclusive discrimination between
r≥2 arbitrary quantum states under a noisy communication. As an example, we analyze analytically and numerically a two-sequential conclusive discrimination between two qubit states via depolarizing quantum channels. The derived new general results are important both from the theoretical point of view and for the development of a successful multipartite quantum communication via noisy quantum channels.