Quantum Computing Applications for Large-Scale Drug Utilization Review
Sravan Kumar Nidiganti
Drug Utilization Review (DUR) is needed within health care to assess prescribing, dispensing, and medication practices, and to determine if those practices are safe, effective, and affordable.The scale of DUR is currently growing, and will continue to grow with the availability of electronic health records (EHR), claims and real world evidence (RWE).As this scale increases, so do the challenges surrounding contracting with high dimensional data and identifying intricate relationships (e.g.polypharmacy, drug-disease interactions).These challenges are in part due to the current paradigm of classical computers.Quantum Computing (QC) creates the opportunity to advanced these challenges due to its ability to work through massive amounts of information and solve problems on the fly.Under this premise, this work explores the potential role of QC, specifically hybrid quantum-classical models, in the advancement of large scale DUR.This includes the current state of the QC drug discovery and computational chemistry DUR, the application QC could provide to several key DUR challenges, and the creation of a conceptual model which incorporates QC into the current state of DUR.The work also discusses the current state technical, regulatory, and practical impediments to the QC use case within health care, the foundational research needed to closed these gaps, and the use case benefits the work seeks to enable.Ultimately, this work creates a path to the integration of QC and the optimization of drug utilization practices to improve health systems cost effectiveness and patient outcomes.
International Journal of Drug Delivery Technology•Jul 30, 2026•0 citations