Summary form only given, as follows. The complete presentation was not made available for publication as part of the conference proceedings. Quantum computing has the potential to achieve breakthroughs in simulation, optimization, machine learning, finance, cybersecurity, medical science and healthcare, logistics, transportation, and many more. Over the last five years, quantum computing has evolved from a field of scientific research to a full-fledged technology industry. Much progress is still needed to solve real-world problems with quantum technology and achieve true blue quantum advantage. Industry, governments and universities are all experimenting with advanced quantum computing technology to become quantum ready and eventually achieve quantum advantage. They combine quantum and classical approaches to form hybrid models, architectures, runtimes, algorithms and techniques to overcome the limitations NISQ (noisy intermediate quantum) computers thereby integrating internet accessible HPC centers and quantum clouds provided by IBM Quantum, D-Wave Systems, Microsoft Azure, Honeywell, Google, Rigetti, Amazon Braket, Xanadu, or IonQ. Such hybrid approaches are rapidly emerging to explore quantum computing killer applications, such as molecule simulations and exponential algorithm speed-up for hard problems. In this talk, we will discuss challenges and opportunities in the realm of hybrid quantum-classical computing when integrating HPC and quantum computing platforms in the quest of achieving quantum advantage through scalable infrastructure.
Summary form only given, as follows. The complete presentation was not made available for publication as part of the conference proceedings. Quantum computing has the potential to achieve breakthroughs in simulation, optimization, machine learning, finance, cybersecurity, medical science and healthcare, logistics, transportation, and many more. Over the last five years, quantum computing has evolved from a field of scientific research to a full-fledged technology industry. Much progress is still needed to solve real-world problems with quantum technology and achieve true blue quantum advantage. Industry, governments and universities are all experimenting with advanced quantum computing technology to become quantum ready and eventually achieve quantum advantage. They combine quantum and classical approaches to form hybrid models, architectures, runtimes, algorithms and techniques to overcome the limitations NISQ (noisy intermediate quantum) computers thereby integrating internet accessible HPC centers and quantum clouds provided by IBM Quantum, D-Wave Systems, Microsoft Azure, Honeywell, Google, Rigetti, Amazon Braket, Xanadu, or IonQ. Such hybrid approaches are rapidly emerging to explore quantum computing killer applications, such as molecule simulations and exponential algorithm speed-up for hard problems. In this talk, we will discuss challenges and opportunities in the realm of hybrid quantum-classical computing when integrating HPC and quantum computing platforms in the quest of achieving quantum advantage through scalable infrastructure.
The convergence of quantum computing and cloud platforms represents a significant paradigm shift in the landscape of digital services, creating unprecedented opportunities for technological advancement. This article provides an extensive review of this integration, examining its technological underpinnings, the current state of commercial and public-sector services, emerging applications, and the persistent challenges that define its developmental trajectory. By synthesizing recent academic literature, detailed industry reports, and policy analyses, we explore the transition from theoretical concepts to practical, accessible quantum systems. We detail the progress made in the Noisy Intermediate-Scale Quantum (NISQ) era, marked by significant hardware advancements from leaders like IBM and Google, and the development of crucial error mitigation techniques that extend the utility of current processors. Key findings indicate that cloud access is the primary mechanism for democratizing quantum resources, accelerating research, and enabling the exploration of high-value use cases in sectors such as finance, pharmaceuticals, and manufacturing. Furthermore, we investigate the growing adoption by non-profit organizations to tackle complex social and environmental challenges. However, substantial hurdles related to quantum decoherence, hardware scalability, software architecture, and the quantum-classical interface remain. The discussion contextualizes these findings, highlighting the strategic importance of national policies, the industry's push towards fault-tolerant systems, and the long-term vision of hybrid quantum-classical supercomputing. We conclude that while the path to achieving full-scale, fault-tolerant quantum computing is long and complex, its integration with cloud infrastructure is the critical catalyst, paving the way for a new frontier in computational capability and societal problem-solving.
Hybrid computing models, which integrate both classical and quantum systems, represent a promising frontier in enhancing computational power and efficiency. Classical computing systems, while highly efficient for a broad range of tasks, encounter significant limitations when addressing complex, large-scale problems such as optimization, cryptography, and molecular simulations. Quantum computing, on the other hand, offers exponential speedup for specific algorithms, particularly in areas like factorization, search, and simulation of quantum systems. However, quantum systems are not yet mature enough to replace classical systems entirely, due to issues like error rates, qubit coherence, and the need for cryogenic environments. As a result, hybrid models are emerging as the most viable solution, combining the strengths of both paradigms to tackle computationally intensive tasks more efficiently. This paper provides a comprehensive analysis of the development and application of hybrid computing models. It explores how these models leverage the parallel processing power of quantum systems while utilizing the robustness and data handling capabilities of classical systems. We discuss various architectures proposed for hybrid computing, focusing on their scalability, efficiency, and real-world applications across industries such as healthcare, finance, cryptography, and artificial intelligence. Additionally, we examine the challenges involved in integrating classical and quantum systems, including synchronization, resource management, and algorithm development. The paper concludes with future directions for hybrid computing, emphasizing the potential for these models to revolutionize fields that rely on high-performance computing by offering unprecedented computational capabilities. In summary, hybrid computing models stand at the intersection of classical and quantum technologies, providing a synergistic approach to solving some of the most challenging computational problems faced today.
Quantum computing has emerged as a transformative computational paradigm capable of addressing limitations increasingly encountered by classical computing systems as Moore’s law approaches physical and economic constraints. By leveraging quantum mechanical principles such as superposition, entanglement, and interference, quantum systems offer the potential for significant computational advantages in solving complex problems that are currently infeasible for conventional architectures. This review critically synthesizes recent advances in quantum computing by examining foundational principles, major algorithmic breakthroughs, evolving hardware platforms, and interdisciplinary real-world applications. A structured narrative literature review was conducted using major scientific databases, including PubMed, IEEE Xplore, Nature, ScienceDirect, and arXiv, with emphasis on peer-reviewed studies, landmark foundational research, and major industry developments published between 2018 and 2026. Key findings indicate substantial progress in superconducting, trapped ion, photonic, and topological quantum systems, alongside innovations in algorithms such as Shor’s, Grover’s, variational quantum methods, and quantum machine learning. Despite these advancements, major challenges including decoherence, noise, scalability limitations, and fault-tolerant error correction remain substantial barriers to commercial maturity. Future implications suggest quantum computing may profoundly influence artificial intelligence, cybersecurity, optimization, molecular simulation, and scientific discovery, particularly through hybrid classical-quantum systems and cloud-based democratization. Although practical deployment remains transitional, quantum computing is positioned to become a foundational technology with broad scientific, industrial, and societal implications.
The rapid advancement of quantum computing technology presents an opportunity to revolutionize cloud computing platforms, enabling the execution of complex workloads that are beyond the reach of classical systems. This paper explores the potential of quantum-enhanced cloud platforms, focusing on bridging classical and quantum computing to support future workloads. We examine the integration of quantum processors with classical cloud infrastructure, highlighting the challenges and benefits of hybrid architectures that combine the strengths of both paradigms. Key topics include quantum resource management, quantum programming models, and the development of algorithms that leverage quantum speedup for optimization, machine learning, and data analysis. Additionally, we address the scalability, security, and interoperability concerns that must be overcome for effective deployment in real-world cloud environments. By offering insights into the convergence of classical and quantum computing, this paper provides a roadmap for the evolution of cloud platforms capable of supporting next-generation applications and workloads.
Abstract: This article presents a comprehensive review of the integration of quantum computing with High-Performance Computing (HPC), examining current trends, challenges, and future directions. We explore the fundamental principles of quantum computing and their relevance to HPC, followed by an analysis of state-of-the-art quantum algorithms and hybrid quantum-classical systems. The article addresses key technical challenges in hardware and software integration, as well as scalability and stability issues in quantum-enhanced HPC systems. Through a series of case studies, we demonstrate the practical applications and potential impact of quantum-HPC integration across various industries, including finance, drug discovery, and logistics. Our findings highlight the transformative potential of quantum computing in HPC, suggesting unprecedented improvements in computational speed and efficiency. The article concludes with an overview of emerging quantum technologies and identifies promising research opportunities, emphasizing the importance of collaboration between academia and industry. This work serves as a valuable resource for researchers, engineers, and industry professionals seeking to understand and leverage the synergy between quantum computing and HPC, paving the way for future innovations in computational capabilities
Quantum computing is a paradigm shift in computational science, where computational tasks that cannot be computationally tackled with binary computing systems can be tackled using quantum mechanics principles, including superposition, entanglement, and quantum interference. The present paper gives a comprehensive summary of the present condition of quantum computing, including the most advanced hardware systems, such as topological qubits, photonics processors, trapped-ion systems and superconducting qubits, and their corresponding advantages and technical challenges. Also, quantum algorithms, including the Quantum Approximate Optimization Algorithm (QAOA) and the variational quantum eigen solvers (VQE), include a summary of the first algorithm, Shor's factorization method, and the second algorithm, Grover's search algorithm. Applications of such algorithms are evaluated in such areas as financial modeling, machine learning, material science, drug discovery, and cryptography. Taking into account the information provided by large research facilities and technology firms, the conditions under which quantum systems can outperform conventional technology, such a concept as quantum advantage is given specific focus in this review. Moreover, this paper pays particular attention to the key barriers to effective implementation, such as qubit decoherence, large error rates, scalability issues, and the lack of fault-tolerant quantum devices that can be sold commercially. Regarding the noisy intermediate-scale quantum (NISQ) devices that are expected to be available in the near future, we discuss novel approaches to quantum error correction, especially surface code and concatenated code. The quantum software industry, such as IBM Qiskit, Google Cirq, and Microsoft Q, and an evaluation of quantum workforce and research facility readiness across the globe is also discussed. In the end, this work highlights essential potential future paths, such as standards for post-quantum cryptography, hybrid quantum-classical computation, quantum networking and the quantum internet, and the long-term aims for universal fault- tolerant quantum computers. The review should provide researchers, graduate students, and practitioners with a systematic and up-to-date base to understand the fast-growing discipline of quantum computing and its extensive implications on science and business.