Challenges
Datasets
Workspaces
Papers
Discussions
Leaderboard
Log inSign up
Challenges
Datasets
Workspaces
Papers
Discussions
Leaderboard
Blog
Job Board
Q3AS

© 2026 Aqora Quantum S.A.S.

TermsPrivacyLegal Notice

Expert Systems with Applications

Hybrid classical–quantum Convolutional Neural Network for stenosis detection in X-ray coronary angiography

Emmanuel Ovalle-Magallanes, Juan Gabriel Avina‐Cervantes, Iván Cruz-Aceves, José Ruiz-Pinales

Published Oct 28, 2021• 96 citations
Publisher
DOI
10.1016/j.eswa.2021.116112

Related papers

Hybrid classical–quantum neural networks enhanced by quantum architecture search for coronary artery stenosis detection

Shao‐Chun Li, Junzhi Cui, Jingli Ren

Neurocomputing•Dec 7, 2024•16 citations

Hybrid quantum-classical convolutional neural networks for multiclass lung X-ray image classification

Ariiq Islam Alfajri, Tony Ibnu Sumaryada, Sitti Yani +3 more

Journal of Radiation Research and Applied Sciences•Jan 13, 2026•3 citations

Hybrid quantum-classical 3D object detection using multi-channel quantum convolutional neural network

Emily Jimin Roh, Joo Yong Shim, Joongheon Kim +1 more

The Journal of Supercomputing•Feb 1, 2025•9 citations

A Hybrid Quantum Convolutional Neural Network Model for Detecting Covid-19 from Chest Radiographs Images

Madhulata Kumari, Kanad Ray, Saurav Mallik +1 more

Lecture notes in networks and systems•Nov 20, 2025•0 citations

Quantum Preprocessing for Deep Convolutional Neural Networks in Atherosclerosis Detection

Siddhartha Bhattacharyya, Mario Köppen, Elizabeth Behrman +1 more

Coronary artery disease is the leading cause of mortality rate worldwide. This condition is caused by an abnormal narrowing or occlusion of the artery lumen, known as atherosclerosis (a specific type of stenosis). Currently, many imaging techniques have been tested; nevertheless, conventional X-ray Coronary Angiography (XCA) remains the gold standard for coronary artery disease diagnosis, such as atherosclerosis. This study presents a Hybrid Quantum-Convolutional Neural Network to detect coronary artery atherosclerosis in XCA images automatically. It employs a Quantum Convolutional Layer (QCL) that resembles a typical Convolutional Layer. However, unlike the convolution operation where a classical convolutional filter is applied, a QCL transforms the input using a quantum circuit. This QCL generates a multichannel image from a single channel XCA that feeds a traditional Convolutional Neural Network (CNN). The CNN was trained and optimized using two different architectures previously employed for atherosclerosis detection, viz. a DenseNet-based and a VGG-based architectures. Additionally, a comparison of Stochastic Gradient Descent (SGD) and SGD with Momentum (SGDM) were conducted. These architectures were analyzed and compared using a real dataset composed of 250 real XCA images (split into 125 images for testing and 125 for training) regarding their training without the QCL preprocessing and SGDM. The results showed that the CNNs trained with the outcome of the QCL surpasses the baseline CNNs performance. Herein, the best atherosclerosis detection reached an accuracy of 83.36%, while in other metrics such as precision, sensitivity, specificity, and F1-score, achieved an 81.52%, 86.67%, 83.99%, and 80.00%, respectively.

CRC Press eBooks•Mar 31, 2022•0 citations

Lightweight Quantum-Enhanced ResNet for Coronary Angiography Classification: A Hybrid Quantum-Classical Feature Enhancement Framework

Jingsong Xia

Background: Coronary angiography (CAG) is the cornerstone imaging modality for evaluating coronary artery stenosis and guiding interventional decision-making. However, interpretation based on single-frame angiographic images remains highly operator-dependent, and conventional deep learning models still face challenges in modeling complex vascular morphology and fine-grained texture patterns.Methods: We propose a Lightweight Quantum-Enhanced ResNet (LQER) for binary classification of coronary angiography images. A pretrained ResNet18 is employed as a classical feature extractor, while a parameterized quantum circuit (PQC) is introduced at the high-level semantic feature space for quantum feature enhancement. The quantum module utilizes data re-uploading and entanglement structures, followed by residual fusion with classical features, enabling end-to-end hybrid optimization with a strictly controlled number of qubits.Results: On an independent test set, the proposed LQER outperformed the classical ResNet18 baseline in accuracy, AUC, and F1-score, achieving a test accuracy exceeding 90%. The results demonstrate that lightweight quantum feature enhancement improves discrimination of positive lesions, particularly under class-imbalanced conditions.Conclusion: This study validates a practical hybrid quantum--classical learning paradigm for coronary angiography analysis, providing a feasible pathway for deploying quantum machine learning in medical imaging applications.

quant-pharXiv:2601.18814•Jan 23, 2026•0 citations
Coronary artery disease is the leading cause of mortality rate worldwide. This condition is caused by an abnormal narrowing or occlusion of the artery lumen, known as atherosclerosis (a specific type of stenosis). Currently, many imaging techniques have been tested; nevertheless, conventional X-ray Coronary Angiography (XCA) remains the gold standard for coronary artery disease diagnosis, such as atherosclerosis. This study presents a Hybrid Quantum-Convolutional Neural Network to detect coronary artery atherosclerosis in XCA images automatically. It employs a Quantum Convolutional Layer (QCL) that resembles a typical Convolutional Layer. However, unlike the convolution operation where a classical convolutional filter is applied, a QCL transforms the input using a quantum circuit. This QCL generates a multichannel image from a single channel XCA that feeds a traditional Convolutional Neural Network (CNN). The CNN was trained and optimized using two different architectures previously employed for atherosclerosis detection, viz. a DenseNet-based and a VGG-based architectures. Additionally, a comparison of Stochastic Gradient Descent (SGD) and SGD with Momentum (SGDM) were conducted. These architectures were analyzed and compared using a real dataset composed of 250 real XCA images (split into 125 images for testing and 125 for training) regarding their training without the QCL preprocessing and SGDM. The results showed that the CNNs trained with the outcome of the QCL surpasses the baseline CNNs performance. Herein, the best atherosclerosis detection reached an accuracy of 83.36%, while in other metrics such as precision, sensitivity, specificity, and F1-score, achieved an 81.52%, 86.67%, 83.99%, and 80.00%, respectively.
Background: Coronary angiography (CAG) is the cornerstone imaging modality for evaluating coronary artery stenosis and guiding interventional decision-making. However, interpretation based on single-frame angiographic images remains highly operator-dependent, and conventional deep learning models still face challenges in modeling complex vascular morphology and fine-grained texture patterns.Methods: We propose a Lightweight Quantum-Enhanced ResNet (LQER) for binary classification of coronary angiography images. A pretrained ResNet18 is employed as a classical feature extractor, while a parameterized quantum circuit (PQC) is introduced at the high-level semantic feature space for quantum feature enhancement. The quantum module utilizes data re-uploading and entanglement structures, followed by residual fusion with classical features, enabling end-to-end hybrid optimization with a strictly controlled number of qubits.Results: On an independent test set, the proposed LQER outperformed the classical ResNet18 baseline in accuracy, AUC, and F1-score, achieving a test accuracy exceeding 90%. The results demonstrate that lightweight quantum feature enhancement improves discrimination of positive lesions, particularly under class-imbalanced conditions.Conclusion: This study validates a practical hybrid quantum--classical learning paradigm for coronary angiography analysis, providing a feasible pathway for deploying quantum machine learning in medical imaging applications.