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Nature Computational Science

Reducing qubit budget in quantum machine learning

Jie Pan

Published Sep 16, 2021• 0 citations
Publisher
DOI
10.1038/s43588-021-00133-9

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Despite significant progress in quantum computing in recent years, executing quantum circuits for practical problems remains challenging due to error-prone quantum hardware. Hence, quantum error correction becomes essential but induces significant overheads in qubits and execution time, often by orders of magnitude. Obviously, these overheads must be reduced. Since many quantum applications can tolerate some noise, end users can provide a maximum tolerated error, the error budget, to be considered during compilation and execution. This error budget, or, more precisely, its distribution, can be a key factor in achieving the overhead reduction. Conceptually, an errorcorrected quantum circuit can be divided into different parts that each have a specific purpose. Errors can happen in any of these parts and their errors sum up to the mentioned error budget-but how to distribute it among them actually constitutes a degree of freedom. This work is based on the idea that some of the circuit parts can compensate for errors more efficiently than others. Consequently, these parts should contribute more to satisfy the total error budget than the parts where it is more costly. However, this poses the challenge of finding optimal distributions. We address this challenge not only by providing general guidelines on distributing the error budget, but also a method that automatically determines resource-efficient distributions for arbitrary circuits by training a machine learning model on an accumulated dataset. The approach is evaluated by analyzing the machine learning model's predictions on so far unseen data, reducing the estimated space-time costs for more than 75% of the considered quantum circuits, with an average reduction of15.6%\mathbf{1 5. 6 \%}15.6%, including cases without improvement, and a maximum reduction of77.7%\mathbf{7 7. 7 \%}77.7%.
Clinical registries and wearable sensors support early health-risk assessment, yet models trained on these records may leak sensitive information when released. Differential privacy (DP) bounds this leakage by injecting noise whose total magnitude grows with the number of trainable parameters, a cost especially severe for small health cohorts. This motivates parameter efficient models including quantum machine learning (QML), whose variational circuits can represent complex decision boundaries with few trainable parameters. It raises a question: at matched input dimensionality and privacy budget, does a quantum model retain more utility than a classical one? We investigate this question on three clinical cohorts and one wearable cohort, treating each clinical record or participant as a privacy unit. We compare capacity-matched quantum, multilayer perceptron, and logistic regression models across five privacy budgets and five seeds. The quantum model leads on three clinical cohorts by up to 0.104 ROC AUC averaged across budgets; however, trails on the wearable cohort, where the small number of participants requires substantial noise. No difference survives Holm correction across 24 tests, so these results indicate a trend rather than a quantum advantage. An analytic gradient bound shows that lower clipping thresholds can improve utility by reducing noise despite clipping bias. Finally, an experiment on IBM quantum computer (ibm_fez, a 156-qubit superconducting processor) using eight fixed test cases yields mean absolute probability errors of 0.046 (private) and 0.063 (non-private) relative to simulation, supporting the feasibility of inference on noisy intermediate-scale quantum (NISQ) hardware. Code is publicly available at https://github.com/TITANS-Lab-Artifacts/DP-QML-Health.