Affine transformations (dilatations and translations) are used to define a deformation of one-dimensional
N=2 supersymmetric quantum mechanics. Resulting physical systems do not have conserved charges and degeneracies in the spectra. Instead, superpartner Hamiltonians are
q-isospectral, i.e. the spectrum of one can be obtained from another (with possible exception of the lowest level) by
q2-factor scaling. This construction allows easily to rederive a special self-similar potential found by Shabat and to show that for the latter a
q-deformed harmonic oscillator algebra of Biedenharn and Macfarlane serves as the spectrum generating algebra. A general class of potentials related to the quantum conformal algebra
suq(1,1) is described. Further possibilities for
q-deformation of known solvable potentials are outlined. Talk presented at the workshop on Harmonic Oscillators, College Park, 25-28 March 1992.