Orthodox Copenhagen quantum theory renounces the quest to understand the reality in which we are imbedded, and settles for practical rules that describe connections between our observations. However, an examination of certain nonlocal features of quantum theory suggests that the perceived need for this renunciation was due to the uncritical importation from classical physics of a crippling metaphysical prejudice, and that rejection of that prejudice opens the way to a dynamical theory of the interaction between mind and brain that has significant explanatory power.