Torsion and entropy driven denaturation of DNA

Michelle X. Yang

Subhamoy Singha Roy, Pratul Bandyopadhyay

The conformational properties of a DNA molecule when mapped onto a Heisenberg spin system denaturation transition can be formulated in terms of quantum phase transition induced by a quench where the temperature effect is incorporated in the quench time. Here torsion takes on the role of the external field. The denaturation transition occurs when the entanglement entropy of the spin system vanishes. As the critical region corresponds to a two-limit behaviour the entanglement entropy gradually decreases with the gradual increase in the fraction of open base pairs and when the entropy vanishes the two strands are separated. The sequence heterogeneity interplays with the entropy effects and we have the onset of denaturation bubbles. We have studied the melting profiles for different sequence-specific DNA molecules and the results are found to be in excellent agreement with experiment.

S. Zdravkovi

Subhamoy Singha Roy, Sania Parveen, Saiberi Farhan Khan

When a DNA molecules conformational characteristics are charted adjacent to a Heisenberg-spin-system, the denaturation shift be able to be expressed in stipulations of a QFT (quantum-phase-transition) brought on through a quench, in which the external field is torsion and the temperature effect is integrated into the quench time. When the spin system's entanglement entropy disappears, the denaturation transition takes place. The energy of torsion includes temperature, stress, and torque, the latter of which is correlated with the twist angle. A DNA molecule put on the Heisenberg spin chain experiences torsion as the outer field. When the EE (entanglement entropy) disappears, the transition to denaturation takes place. The entanglement entropy steadily drops as the proportion of unlock stand pairs gradually increases, the two strands split until the entropy disappears, since the dangerous area corresponding to a 2-boundary actions. The melting profiles of specific DNA molecules have been examined, and the findings show great agreement with biotechnology.

Faisal Harold O. Haider, Micah Danielle Lojera

Subhamoy Singha Roy, Spandan Karfa, Srija Nandi +5 more

One approach to imagine spins on the axis generating an antiferomagnatic chain is described as simulating a DNA molecule as a Heisenberg spin system. In a DNA molecule, the entanglement entropy of the spin system is shown to be in good agreement with the thermodynamic entropy. At times when the impact of temperature is included during the time of quench, It is shown that denaturation corresponds to a quantum phase change triggered by a quench. The critical point is attained and When the entanglement entropy is eliminated, it equates to a critical torsonal energy. DNA loops now appear as solitonic (skyrmionic) excitations upon base pair opening.