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Journal of Integrative Neuroscience

QUANTUM MECHANICS AND BRAIN UNCERTAINTY

Ronald J. MacGregor

Published Sep 1, 2006• 15 citations
Publisher

Abstract

This paper argues that molecular governing structures (such as receptors, gating molecules, or ionic channels) which operate pervasively in the brain, often with small number particle systems (as, for example, at the surfaces of membranes, synaptic clefts, or macromolecules), may plausibly be vehicles for the transmutation of quantum mechanical fluctuations to normal-level neural signaling.

DOI
10.1142/s0219635206001215

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This paper argues that molecular governing structures (such as receptors, gating molecules, or ionic channels) which operate pervasively in the brain, often with small number particle systems (as, for example, at the surfaces of membranes, synaptic clefts, or macromolecules), may plausibly be vehicles for the transmutation of quantum mechanical fluctuations to normal-level neural signaling.
Abstract. It is shown that if mental influence can change a position or momentum coordinate within the limits of the uncertainty principle, such change, when magnified by a single interaction, is sufficient to order the direction of traveling molecules. Mental influence could initiate an action potential in the brain through this process by using the impact of ordered molecules to open the gates of sodium channels in neuronal membranes. It is shown that about 80 ordered molecules, traveling at thermal velocity in the intercellular medium in the brain, can break an ionic or covalent bond, and that the number needed to initiate an action potential is relatively small. If mental influence can act within the brain, it is reasonable to suppose it can act to some extent outside of it. If mental influence could not only order the direction of individual molecules, but coordinate this effect to produce a longitudinal pressure wave which is reasonably coherent across a macroscopic surface, only 104 molecules need be simultaneously affected to produce a detectible sound wave. Such an effect is not ordinarily observed, which suggests that if mental influence acts by ordering the direction of molecules, it acts at the level of individual molecules, but does not coordinate their motion.
Abstract A human brain operates as a pattern of switching. An abstract definition of a quantum mechanical switch is given that allows for the continual random fluctuations in the warm wet environment of the brain. Among several switch-like entities in the brain, I choose to focus on the sodium channel proteins. After explaining what these are, I analyse the ways in which my definition of a quantum switch can be satisfied by portions of such proteins. I calculate the perturbing effects of normal variations in temperature and electric field on the quantum state of such a portion. These are shown to be acceptable within the fluctuations allowed for by my definition. Information processing and unpredictability in the brain are discussed. The ultimate goal underlying the paper is an analysis of quantum measurement theory based on an abstract definition of the physical manifestations of consciousness. The paper is written for physicists with no prior knowledge of neurophysiology, but enough introductory material has also been included to allow neurophysiologists with no prior knowledge of quantum mechanics to follow the central arguments.
The gut-brain axis is the communication link between the gut and the brain. Although it is known that the gut-brain axis plays a pivotal role in homeostasis, its overall mechanism is still not known. However, for neural synapses, classical molecular communication is described by the formation of ligand-receptor complexes, which leads to the opening of ion channels. Moreover, there are some conditions that need to be fulfilled before the opening of the ion channel. In this study, we consider the gut-brain axis, where neurotransmitters diffuse through the synaptic cleft, considering molecular communication. On the vagus nerve (VN) membrane, i.e., the post-synaptic membrane of the synapse, it undergoes a quantum communication (QC), which initiates the opening of the ion channel, thus initiating the communication signal from the gut to the brain. It evolves a new paradigm of communication approach, Molecular Quantum (MolQ) communication. Based on the QC model, we theoretically analyze the output states, and QC is simulated considering the incoming neurotransmitter’s concentration and validated by analyzing the entropy and the mutual information of the input, i.e., neurotransmitter’s concentration, and output, i.e., ion channel opening.