Correlation spectrosopy of single eitters : fundamental studies and applications related to quantum optics and life science

Hans Blom

Published Jan 1, 2003• 0 citations

OpenAlex

Abstract

Related papers

Correlation spectroscopy of single emitters : fundamental studies and applications

Hans Blom

Jan 1, 20010 citations

Elliptical line focus in fluorescence spectroscopy : theory and application

Hans Blom, Niklas Bark, Michael Gösch +5 more

Correlation analysis and correlation spectroscopy has eversince the first developments, to characterise light emittingprocesses and biomolecular dynamics, continued to extend itspractical applicability. Today, correlation spectroscopy can beused in life science to study dynamical processes even at thesingle molecule level. Correlation analysis can in one of itsextreme be applied to investigate single photon processes fromsolid-state emitters. This thesis is an account of my studiesof fluorescent emitter related to quantum optics and lifescience. It presents some fundamental results and discussesapplications of emitters like single quantum dots or singledyes attached to biomolecules. The studies were performed bythe means of correlation analysis and correlation spectroscopyon self-made optical setups. One task of this thesis was todevelop fluorescence correlation spectroscopy for ultravioletexcitation and emission. With ultraviolet excitation thenatural intrinsic chromophores of certain nucleotides and aminoacids can be used. No external labelling of biomolecules couldbecome a reality using ultraviolet excitation and emission. Asecond task was to apply correlation spectroscopy to performhigh spatial-resolution flow profiling and trafficking ofsingle dye-labeled biomolecules in microstructured channels.Future transports effects, flow monitoring, flow profiling andprolonged fluorescence detection in artificial microstructuresor in cells, could benefit from this application. An additionaltask was to apply correlation spectroscopy to so-calledmicroarrays for parallel acquisition of dynamical data at thesingle molecule level. Parallel excitation and detection wasachieved with the use of diffractive optical elements andintegrated semiconductor single-photon sensitive detectors. Thecurrent throughput rate in biological diagnostic or screeninganalysis could be increased dramatically with implementation ofthis parallel confocal excitation and detection technique. Yetanother task of this thesis was to investigations single-photongeneration by InAs-semiconductor quantum dots. We show that aquantum dots can be used for single-photon generation ondemand. Besides the single-photon generation in quantum dots,the possibility of two-photon generation, and generation ofentangled photon-pair, has also been investigated

Jan 1, 20100 citations

Single-nanocrystal photon correlation : a versatile tool for elucidating basic physics and characterizing applications-relevant properties

Andrew P. Beyler

Jan 1, 20151 citation

Applications of single photons in quantum metrology, biology and the foundations of quantum physics

Christophe Couteau, Stefanie Barz, Thomas Durt +6 more

Nature Reviews PhysicsMay 26, 202381 citations

Foundations of Quantum Optics for Quantum Information: Crash Course on Nonclassical States and Quantum Correlations

Jhoan Eusse, Esteban Vasquez, Tom Rivlin +1 more

Nonclassical states of light and their correlations lie at the heart of quantum optics, serving as fundamental resources that underpin both the exploration of quantum phenomena and the realisation of quantum information protocols. These lecture notes provide an accessible yet rigorous introduction to the foundations of quantum optics, emphasising their relevance to quantum information science and technology. Starting from the quantisation of the electromagnetic field and the bosonic formalism of Fock space, the notes develop a unified framework for describing and analysing quantum states of light. Key families of states -- thermal, coherent, and squeezed -- are introduced as paradigmatic examples illustrating the transition from classical to nonclassical behaviour. The concepts of convexity, classicality, and quasiprobability representations are presented as complementary tools for characterising quantumness and defining operational notions such as P-nonclassicality. The discussion extends naturally to Gaussian states, composite systems, and continuous-variable entanglement, highlighting how nonclassicality serves as a resource for generating and quantifying quantum correlations. Theoretical developments are complemented by computational and experimental perspectives, including simulations of optical states using the Python library Strawberry Fields and data analysis from simulated data. Together, these notes aim to bridge the foundational concepts of quantum optics and modern quantum information, offering both conceptual insight and practical tools for students and researchers entering the field.

quant-pharXiv:2601.20619Jan 29, 20260 citations

Fluorescence correlation spectroscopy with Lorentzian intensity distribution

Hans Blom, Gunnar G. Bjork, Michael Gösch +1 more

Correlation analysis and correlation spectroscopy has eversince the first developments, to characterise light emittingprocesses and biomolecular dynamics, continued to extend itspractical applicability. Today, correlation spectroscopy can beused in life science to study dynamical processes even at thesingle molecule level. Correlation analysis can in one of itsextreme be applied to investigate single photon processes fromsolid-state emitters. This thesis is an account of my studiesof fluorescent emitter related to quantum optics and lifescience. It presents some fundamental results and discussesapplicationsof emitters like single quantum dots or singledyes attached to biomolecules. The studies were performed bythe means of correlation analysis and correlation spectroscopyon self-made optical setups. One task of this thesis was todevelop fluorescence correlation spectroscopy for ultravioletexcitation and emission. With ultraviolet excitation thenatural intrinsic chromophores of certain nucleotides and aminoacids can be used. No external labelling of biomolecules couldbecome a reality using ultraviolet excitation and emission. Asecond task was to apply correlation spectroscopy to performhigh spatial-resolution flow profiling and trafficking ofsingle dye-labeled biomolecules in microstructured channels.Future transports effects, flow monitoring, flow profiling andprolonged fluorescence detection in artificial microstructuresor in cells, could benefit from this application. An additionaltask was to apply correlation spectroscopy to so-calledmicroarrays for parallel acquisition of dynamical data at thesingle molecule level. Parallel excitation and detection wasachieved with the use of diffractive optical elements andintegrated semiconductor single-photon sensitive detectors. Thecurrent throughput rate in biological diagnostic or screeninganalysis could be increased dramatically with implementation ofthis parallel confocal excitation and detection technique. Yetanother task of this thesis was to investigations single-photongeneration by InAs-semiconductor quantum dots. We show that aquantum dots can be used for single-photon generation ondemand. Besides the single-photon generation in quantum dots,the possibility of two-photon generation, and generation ofentangled photon-pair, has also been investigated.

Jan 1, 20100 citations

Correlation analysis and correlation spectroscopy has eversince the first developments, to characterise light emittingprocesses and biomolecular dynamics, continued to extend itspractical applicability. Today, correlation spectroscopy can beused in life science to study dynamical processes even at thesingle molecule level. Correlation analysis can in one of itsextreme be applied to investigate single photon processes fromsolid-state emitters. This thesis is an account of my studiesof fluorescent emitter related to quantum optics and lifescience. It presents some fundamental results and discussesapplicationsof emitters like single quantum dots or singledyes attached to biomolecules. The studies were performed bythe means of correlation analysis and correlation spectroscopyon self-made optical setups. One task of this thesis was todevelop fluorescence correlation spectroscopy for ultravioletexcitation and emission. With ultraviolet excitation thenatural intrinsic chromophores of certain nucleotides and aminoacids can be used. No external labelling of biomolecules couldbecome a reality using ultraviolet excitation and emission. Asecond task was to apply correlation spectroscopy to performhigh spatial-resolution flow profiling and trafficking ofsingle dye-labeled biomolecules in microstructured channels.Future transports effects, flow monitoring, flow profiling andprolonged fluorescence detection in artificial microstructuresor in cells, could benefit from this application. An additionaltask was to apply correlation spectroscopy to so-calledmicroarrays for parallel acquisition of dynamical data at thesingle molecule level. Parallel excitation and detection wasachieved with the use of diffractive optical elements andintegrated semiconductor single-photon sensitive detectors. Thecurrent throughput rate in biological diagnostic or screeninganalysis could be increased dramatically with implementation ofthis parallel confocal excitation and detection technique. Yetanother task of this thesis was to investigations single-photongeneration by InAs-semiconductor quantum dots. We show that aquantum dots can be used for single-photon generation ondemand. Besides the single-photon generation in quantum dots,the possibility of two-photon generation, and generation ofentangled photon-pair, has also been investigated.