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Science

Helical Beams Give Particles a Whirl

Sunny Bains

Published Jul 5, 1996• 1 citation
Publisher

Abstract

For the past 25 years, physicists wanting to pick up and hold particles as small as a single molecule have used very precise laser beams in setups known as “optical tweezers.” Now two teams of researchers, in the United Kingdom and in Australia, have found that by using specially sculpted laser beams they can do more than just hold a molecule: They can make it spin, speed up and slow down its spinning, and even bring it to a stop and spin it the other way. The researchers say the technique may one day be useful in nanotechnology and, because it requires less power than conventional optical tweezers, can be used to manipulate living biological tissue without killing it.

DOI
10.1126/science.273.5271.36

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For the past 25 years, physicists wanting to pick up and hold particles as small as a single molecule have used very precise laser beams in setups known as “optical tweezers.” Now two teams of researchers, in the United Kingdom and in Australia, have found that by using specially sculpted laser beams they can do more than just hold a molecule: They can make it spin, speed up and slow down its spinning, and even bring it to a stop and spin it the other way. The researchers say the technique may one day be useful in nanotechnology and, because it requires less power than conventional optical tweezers, can be used to manipulate living biological tissue without killing it.
This important volume contains selected papers and extensive commentaries on laser trapping and manipulation of neutral particles using radiation pressure forces. Such techniques apply to a variety of small particles, such as atoms, molecules, macroscopic dielectric particles, living cells, and organelles within cells. These optical methods have had a revolutionary impact on the fields of atomic and molecular physics, biophysics, and many aspects of nanotechnology.In atomic physics, the trapping and cooling of atoms down to nanokelvins and even picokelvin temperatures are possible. These are the lowest temperatures in the universe. This made possible the first demonstration of Bose–Einstein condensation of atomic and molecular vapors. Some of the applications are high precision atomic clocks, gyroscopes, the measurement of gravity, cryptology, atomic computers, cavity quantum electrodynamics and coherent atom lasers.A major application in biophysics is the study of the mechanical properties of the many types of motor molecules, mechanoenzymes, and other macromolecules responsible for the motion of organelles within cells and the locomotion of entire cells. Unique in vitro and in vivo assays study the driving forces, stepping motion, kinetics, and efficiency of these motors as they move along the cell's cytoskeleton. Positional and temporal resolutions have been achieved, making possible the study of RNA and DNA polymerases, as they undergo their various copying, backtracking, and error correcting functions on a single base pair basis.Many applications in nanotechnology involve particle and cell sorting, particle rotation, microfabrication of simple machines, microfluidics, and other micrometer devices. The number of applications continues to grow at a rapid rate.The author is the discoverer of optical trapping and optical tweezers. With his colleagues, he first demonstrated optical levitation, the trapping of atoms, and tweezer trapping and manipulation of living cells and biological particles.This is the only review volume covering the many fields of optical trapping and manipulation. The intention is to provide a selective guide to the literature and to teach how optical traps really work.
Tightly focused laser beams form optical tweezers that can hold and manipulate individual atoms. They give superb control over microscopic quantum systems and have paved the way for bottom up assembly of few-atom systems. Such assembled systems provide an ideal starting point for many fundamental studies of atomic interactions and few-atom phenomena. Here we review the present stage of these fields, as well as some of the basic experimental techniques required for these experiments Figure from [74].
The techniques of optical trapping and manipulation of neutral particles by lasers provide unique means to control the dynamics of small particles. These new experimental methods have played a revolutionary role in areas of the physical and biological sciences. This paper reviews the early developments in the field leading to the demonstration of cooling and trapping of neutral atoms in atomic physics and to the first use of optical tweezers traps in biology. Some further major achievements of these rapidly developing methods also are considered.
Abstract Many areas of physics—precision measurements, quantum information, and physical chemistry, to name a few—are starting to benefit from the enormous advantages offered by cold and ultracold polar molecules. Molecules have more states, more interactions, and more chemical properties compared to atoms, which make them exciting to study but difficult to tame. In particular, the powerful techniques of atomic laser cooling cannot be naïvely applied to molecules due to their complicated structure. Developments over the past few years have made directly laser cooled and trapped molecules a reality, and now much effort is focused on making these samples larger, denser, and colder—an important step to realizing many of their exciting applications. A careful experimental and numerical study by Truppe et al (2017 New J. Phys. 19 022001 ) demonstrates a significant improvement and advance in understanding of one of the most limiting steps in laser cooling and trapping of molecules—slowing them from a molecular beam to a near-standstill, with small enough kinetic energy that they can be loaded into a trap.
Cold Molecules Arrays of optical tweezers have been used to trap atoms, but trapping and laser-cooling molecules in this setting is tricky. Such an approach would, however, be generalizable to many molecular species. Anderegg et al. created an optical tweezer array of calcium monofluoride molecules, which were laser cooled to their ground state (see the Perspective by Kotochigova). By distinguishing between single and multiple molecules in the tweezers, the researchers were able to observe molecular collisions. Boasting exquisite control over individual molecules, the optical tweezer array platform holds much promise for extending the applications of ultracold molecules. Science , this issue p. [1156][1]; see also p. [1079][2] [1]: /lookup/doi/10.1126/science.aax1265 [2]: /lookup/doi/10.1126/science.aay3989