Quantum processors are being integrated into HPC ecosystems as co-processors, where compilation of quantum circuits into hardware-executable form determines both output fidelity and runtime. Current compilers use a fixed pass sequence and ignore the fact that optimal pass selection varies with circuit, hardware, and noise conditions. We present TuniQ, a reinforcement learning-based system that selects compilation passes at each pipeline stage, adapting to circuit, backend, and current noise profile. TuniQ introduces several novel design components like a dual-encoder for stage-aware representation, shaped rewards for cross-stage credit assignment, and dynamic action masking for valid compilation. Evaluated across diverse quantum workloads on multiple IBM Quantum Cloud processors, TuniQ improves fidelity and reduces compilation time over the state-of-the-art IBM Qiskit transpiler, generalizes across backends without retraining, and scales strongly to utility-scale circuits with growing advantage.
Quantum processors are being integrated into HPC ecosystems as co-processors, where compilation of quantum circuits into hardware-executable form determines both output fidelity and runtime. Current compilers use a fixed pass sequence and ignore the fact that optimal pass selection varies with circuit, hardware, and noise conditions. We present TuniQ, a reinforcement learning-based system that selects compilation passes at each pipeline stage, adapting to circuit, backend, and current noise profile. TuniQ introduces several novel design components like a dual-encoder for stage-aware representation, shaped rewards for cross-stage credit assignment, and dynamic action masking for valid compilation. Evaluated across diverse quantum workloads on multiple IBM Quantum Cloud processors, TuniQ improves fidelity and reduces compilation time over the state-of-the-art IBM Qiskit transpiler, generalizes across backends without retraining, and scales strongly to utility-scale circuits with growing advantage.
High Performance Computing (HPC) and Quantum Computing (QC) systems are increasingly converging towards unified High Performance Computing-Quantum Computing (HPCQC) infrastructures, driven by a growing need to bridge classical and quantum workflows, which affects all levels of the system stack, from the hardware to compilers and runtimes, all the way to applications. However, today's QC devices are still in the Noisy Intermediate-Scale Quantum (NISQ) era, are error-prone and resource-limited, and therefore require specialized optimizations and topology mappings to achieve sufficient fidelity. This places special emphasis on proper compilation and optimization within the overall quantum software stack. Many existing stacks remain fragmented, with separate components responsible for device selection, compiler-pass optimization, and job queue scheduling. This paper proposes a unified, learning-based selector that integrates these disparate stages into a cohesive framework. Our proposed selector scheme leverages reinforcement learning and deep learning models that can be extended to simultaneously optimize multiple objectives -- such as fidelity, compilation time, and scheduling latency -- while dynamically adapting to circuit characteristics and device conditions.
Quantum applications increasingly execute as multi-stage quantum-classical pipelines, interleaving QPU computation with classical stages like circuit generation, transpilation, layout mapping, quantum error mitigation (QEM), and post-processing. These stages have diverse resource requirements and exhibit stochastic behavior under drifting hardware noises, yet existing workflow frameworks treat them as static, isolated components. We present LLQM (Low-Level Quantum Machine), a profiling-driven meta-framework for quantum-classical pipelines. LLQM decomposes pipelines into fine-grained tasks and continuously profiles their CPU/GPU, memory, QPU, and queue dependencies alongside real-time hardware states. This unified runtime abstraction captures cross-stage resource dependencies and reveals how classical and quantum decisions interact, enabling characterization of their impact on fidelity and resource consumption. We evaluate LLQM using QEM as a representative pipeline stage, on IBM 156-qubit Heron r2 processors with circuits up to 100 qubits and 1e7 transpiled gates. Our results show that continuous profiling exposes runtime bottlenecks and enables hardware-, fidelity-, and workload-aware optimizations.
This paper proposes a portable quantum compilation optimization framework based on D3QN (Double Dueling Deep Q-Network) to automate quantum circuit tuning. Addressing challenges in adapting fixed strategies to diverse algorithms, the framework integrates reinforcement learning (RL) with a quantum compiler environment. The RL agent dynamically selects optimization passes, guided by a reward function balancing gate count, circuit depth, and hardware constraints. Quantum circuits are encoded as DAGs, with D3QN estimating Q-values and standardizing action-space encoding, state representation, and constraint validation. Experiments on the MQTBench dataset (430 circuits across 18 algorithms) show the framework outperforms QCOR-O3 and random strategies, achieving an average 8.7% gate reduction. Implemented on QCOR's MLIR-based compiler, the modular design ensures portability. Results validate generalization across algorithms, though performance varies for underrepresented circuits. This work establishes a standardized, RL-driven framework for quantum compilation optimization in NISQ systems.
Quantum software engineering is an emerging research field focusing on efficiently embedding the quantum programming paradigm into existing software ecosystems. A key aspect of this field is the realization of quantum algorithms using gate-based programming and the subsequent low-level optimization of the resulting quantum circuits, a process that is commonly performed by so-called transpilation pipelines. One significant challenge in these pipelines is determining which optimizations to apply to a given circuit. This decision is usually based on fixed default configurations that are uniformly applied to all circuits, frequently resulting in missed opportunities for more aggressive circuit optimization. In this work, we tackle this challenge by applying autotuning with supervised machine learning to develop an automated method for selection of transpiler passes. To train our machine-learning models, we employ feature-model based sampling to generate a representative dataset that examines how different combinations of Qiskit transpiler passes perform across thousands of circuits drawn from the state-of-the-art benchmarking suite MQT Bench. Using these data, we build a predictive model extension for the Qiskit transpilation pipeline that uses a machine learning model to automatically select combinations of transpiler passes aiming to achieve a maximum reduction in two-qubit gates. Our empirical evaluation shows that the combinations selected by our model are never outperformed by Qiskit's optimization levels, achieve on average an additional 19.1% - 32.4% reduction in two-qubit gates, and for some circuits finds reductions of up to 95.8% in cases where Qiskit achieves no reduction at all.
Classical simulation of quantum circuits remains indispensable for algorithm development, hardware validation, and error analysis in the noisy intermediate-scale quantum (NISQ) era. However, state-vector simulation faces exponential memory scaling, with an n-qubit system requiring O(2^n) complex amplitudes, and existing simulators often lack the flexibility to exploit heterogeneous computing resources at runtime. This paper presents a GPU-accelerated quantum circuit simulation framework that introduces three contributions: (1) an empirical backend selection algorithm that benchmarks CuPy, PyTorch-CUDA, and NumPy-CPU backends at runtime and selects the optimal execution path based on measured throughput; (2) a directed acyclic graph (DAG) based gate fusion engine that reduces circuit depth through automated identification of fusible gate sequences, coupled with adaptive precision switching between complex64 and complex128 representations; and (3) a memory-aware fallback mechanism that monitors GPU memory consumption and gracefully degrades to CPU execution when resources are exhausted. The framework integrates with Qiskit, Cirq, PennyLane, and Amazon Braket through a unified adapter layer. Benchmarks on an NVIDIA A100-SXM4 (40 GiB) GPU demonstrate speedups of 64x to 146x over NumPy CPU execution for state-vector simulation of circuits with 20 to 28 qubits, with speedups exceeding 5x from 16 qubits onward. Hardware validation on an IBM quantum processing unit (QPU) confirms Bell state fidelity of 0.939, a five-qubit Greenberger-Horne-Zeilinger (GHZ) state fidelity of 0.853, and circuit depth reduction from 42 to 14 gates through the fusion pipeline. The system is designed for portability across NVIDIA consumer and data-center GPUs, requiring no vendor-specific compilation steps.
Any quantum computing application, once encoded as a quantum circuit, must be compiled before being executable on a quantum computer. Similar to classical compilation, quantum compilation is a sequential process with many compilation steps and numerous possible optimization passes. Despite the similarities, the development of compilers for quantum computing is still in its infancy—lacking mutual consolidation on the best sequence of passes, compatibility, adaptability, and flexibility. In this work, we take advantage of decades of classical compiler optimization and propose a reinforcement learning framework for developing optimized quantum circuit compilation flows. Through distinct constraints and a unifying interface, the framework supports the combination of techniques from different compilers and optimization tools in a single compilation flow. Experimental evaluations show that the proposed framework—set up with a selection of compilation passes from IBM’s Qiskit and Quantinuum’s TKET—significantly outperforms both individual compilers in 73% of cases regarding the expected fidelity. The framework is available on GitHub (https://github.com/cda-tum/MQTPredictor) as part of the Munich Quantum Toolkit (MQT).