Emerging quantum applications such as error mitigation, system characterization, and hybrid protocols often require running large families of related quantum circuits. Existing intermediate representations (IRs) and frameworks such as Qiskit, QIR, MitiQ, and OpenQASM do not provide primitives to concisely express such workloads. These tools instead rely on explicit enumeration of the unique circuits within each workload. We introduce Ensemble-IR, an intermediate representation designed to concisely express these ensemble workloads. Rather than enumerating each circuit separately, Ensemble-IR encodes an entire workload through a rich, shared unified program. This program specifies common circuit structure along with symbolic operations to express points of variation - such as gate types, gate placement, parameter values, or qubit configurations. Ensemble-IR enables quantum systems to load an entire family of circuits onto a device as a single concise file, allowing contained circuits to instead be recreated on-the-fly at runtime. We demonstrate Ensemble-IR across 18 real-world workloads from prior literature, highlighting its widespread utility for scalable quantum system development.
Emerging quantum applications such as error mitigation, system characterization, and hybrid protocols often require running large families of related quantum circuits. Existing intermediate representations (IRs) and frameworks such as Qiskit, QIR, MitiQ, and OpenQASM do not provide primitives to concisely express such workloads. These tools instead rely on explicit enumeration of the unique circuits within each workload. We introduce Ensemble-IR, an intermediate representation designed to concisely express these ensemble workloads. Rather than enumerating each circuit separately, Ensemble-IR encodes an entire workload through a rich, shared unified program. This program specifies common circuit structure along with symbolic operations to express points of variation - such as gate types, gate placement, parameter values, or qubit configurations. Ensemble-IR enables quantum systems to load an entire family of circuits onto a device as a single concise file, allowing contained circuits to instead be recreated on-the-fly at runtime. We demonstrate Ensemble-IR across 18 real-world workloads from prior literature, highlighting its widespread utility for scalable quantum system development.
Abstract Intermediate representations (IRs) are fundamental to classical and quantum computing, bridging high-level quantum programming languages and the hardware-specific instructions required for execution. This paper reviews the development of quantum IRs, focusing on their evolution and the need for abstraction layers that facilitate portability and optimization. Monolithic quantum IRs, such as QIR (Lubinski et al. in Front Phys 10:940293, 2022. https://doi.org/10.3389/fphy.2022.940293), QSSA (Peduri et al. in Proceedings of the 31st ACM SIGPLAN international conference on compiler construction. CC 2022. Association for Computing Machinery, New York, 2022), or Q-MLIR (McCaskey and Nguyen in Proceedings-2021 IEEE International Conference on Quantum Computing and Engineering, QCE, 2021), their effectiveness in handling abstractions, and their hybrid support between quantum-classical operations are evaluated. However, a key limitation is their inability to address qubit locality, an essential feature for distributed quantum computing (DQC). To overcome this, InQuIR (Nishio and Wakizaka in InQuIR: Intermediate Representation for Interconnected Quantum Computers, 2023. https://arxiv.org/abs/2302.00267) was introduced as an IR specifically designed for distributed systems, providing explicit control over qubit locality and inter-node communication. While effective in managing qubit distribution, InQuIR’s dependence on manual manipulation of communication protocols increases complexity for developers. NetQIR (Vázquez-Pérez et al. in NetQIR: An Extension of QIR for Distributed Quantum Computing, 2024. https://arxiv.org/abs/2408.03712), an extension of QIR for DQC, emerges as a solution to achieve the abstraction of quantum communications protocols. This review emphasizes the need for further advancements in IRs for distributed quantum systems, which will play a crucial role in the scalability and usability of future quantum networks.
Quantum computing hardware has progressed rapidly. Simultaneously, there has been a proliferation of programming languages and program optimization tools for quantum computing. Existing quantum compilers use intermediate representations (IRs) where quantum programs are described as circuits. Such IRs fail to leverage existing work on compiler optimizations. In such IRs, it is non-trivial to statically check for physical constraints such as the no-cloning theorem, which states that qubits cannot be copied. We introduce QSSA, a novel quantum IR based on static single assignment (SSA) that enables decades of research in compiler optimizations to be applied to quantum compilation. QSSA models quantum operations as being side-effect-free. The inputs and outputs of the operation are in one-to-one correspondence; qubits cannot be created or destroyed. As a result, our IR supports a static analysis pass that verifies no-cloning at compile-time. The quantum circuit is fully encoded within the def-use chain of the IR, allowing us to leverage existing optimization passes on SSA representations such as redundancy elimination and dead-code elimination. Running our QSSA-based compiler on the QASMBench and IBM Quantum Challenge datasets, we show that our optimizations perform comparably to IBM’s Qiskit quantum compiler infrastructure. QSSA allows us to represent, analyze, and transform quantum programs using the robust theory of SSA representations, bringing quantum compilation into the realm of well-understood theory and practice.
Extreme heterogeneity in emerging HPC systems are starting to include quantum accelerators, motivating runtimes that can coordinate between classical and quantum workloads. We present a proof-of-concept hybrid execution framework integrating the IRIS asynchronous task-based runtime with the XACC quantum programming framework via the Quantum Intermediate Representation Execution Engine (QIR-EE). IRIS orchestrates multiple programs written in the quantum intermediate representation (QIR) across heterogeneous backends (including multiple quantum simulators), enabling concurrent execution of classical and quantum tasks. Although not a performance study, we report measurable outcomes through the successful asynchronous scheduling and execution of multiple quantum workloads. To illustrate practical runtime implications, we decompose a four-qubit circuit into smaller subcircuits through a process known as quantum circuit cutting, reducing per-task quantum simulation load and demonstrating how task granularity can improve simulator throughput and reduce queueing behavior -- effects directly relevant to early quantum hardware environments. We conclude by outlining key challenges for scaling hybrid runtimes, including coordinated scheduling, classical-quantum interaction management, and support for diverse backend resources in heterogeneous systems.
A key challenge of quantum programming is uncomputation: the reversible deallocation of qubits. And while there has been much recent progress on automating uncomputation, state-of-the-art methods are insufficient for handling today's expressive quantum programming languages. A core reason is that they operate on primitive quantum circuits, while quantum programs express computations beyond circuits, for instance, they can capture families of circuits defined recursively in terms of uncomputation and adjoints. In this paper, we introduce the first modular automatic approach to synthesize correct and efficient uncomputation for expressive quantum programs. Our method is based on two core technical contributions: (i) an intermediate representation (IR) that can capture expressive quantum programs and comes with support for uncomputation, and (ii) modular algorithms over that IR for synthesizing uncomputation and adjoints. We have built a complete end-to-end implementation of our method, including an implementation of the IR and the synthesis algorithms, as well as a translation from an expressive fragment of the Silq programming language to our IR and circuit generation from the IR. Our experimental evaluation demonstrates that we can handle programs beyond the capabilities of existing uncomputation approaches, while being competitive on the benchmarks they can handle. More broadly, we show that it is possible to benefit from the greater expressivity and safety offered by high-level quantum languages without sacrificing efficiency.
Hybrid quantum-high performance computing (Q-HPC) workflows are emerging as a key strategy for running quantum applications at scale in current noisy intermediate-scale quantum (NISQ) devices. These workflows must operate seamlessly across diverse simulators and hardware backends since no single simulator offers the best performance for every circuit type. Simulation efficiency depends strongly on circuit structure, entanglement, and depth, making a flexible and backend-agnostic execution model essential for fair benchmarking, informed platform selection, and ultimately the identification of quantum advantage opportunities. In this work, we extend the Quantum Framework (QFw), a modular and HPC-aware orchestration layer, to integrate multiple local backends (Qiskit Aer, NWQ-Sim, QTensor, and TN-QVM) and a cloud-based quantum backend (IonQ) under a unified interface. Using this integration, we execute a number of non-variational as well as variational workloads. The results highlight workload-specific backend advantages: while Qiskit Aer’s matrix product state excels for large Ising models, NWQ-Sim not only leads on large-scale entanglement and Hamiltonian but also shows the benefits of concurrent subproblem execution in a distributed manner for optimization problems. These findings demonstrate that simulator-agnostic, HPC-aware orchestration is a practical path toward scalable, reproducible, and portable Q-HPC ecosystems, thereby accelerating progress toward demonstrating quantum advantage.
We present a tool QSeqSim, a Qiskit-integrated symbolic backend that fills the current gap of having no Qiskit-native support for simulating while-loop quantum programs and their induced sequential quantum circuits. QSeqSim takes Qiskit QuantumCircuit objects, translates them into OpenQASM 3 code, and organises the resulting program into a combination of combinational, dynamic, and sequential circuits, thereby assigning while-loops a precise sequential circuit semantics with explicit internal and external qubits. Building on this semantics, QSeqSim adopts a Binary Decision Diagram (BDD)-based symbolic representation and integrates weighted model counting to compute measurement probabilities efficiently by exploiting sharing in structured and sparse BDDs. On top of this Boolean backbone, it introduces dedicated symbolic operators for state composition and state retention, thereby enabling efficient symbolic execution of sequential quantum circuits. Our experiments demonstrate that QSeqSim scales to substantial while-induced sequential circuits; in particular, in the quantum random walk benchmark we successfully simulate circuits with over 1000 qubits for more than 10 loop iterations.
QSeqSim is available at https://github.com/Veri-Q/QSeqSim.