Hard combinatorial optimization problems, often mapped to Ising models, promise potential solutions with quantum advantage but are constrained by limited qubit counts in near-term devices. We present an innovative quantum-inspired framework that dynamically compresses large Ising models to fit available quantum hardware of different sizes. Thus, we aim to bridge the gap between large-scale optimization and current hardware capabilities. Our method leverages a physics-inspired GNN architecture to capture complex interactions in Ising models and accurately predict alignments among neighboring spins (aka qubits) at ground states. By progressively merging such aligned spins, we can reduce the model size while preserving the underlying optimization structure. It also provides a natural trade-off between the solution quality and size reduction, meeting different hardware constraints of quantum computing devices. Extensive numerical studies on Ising instances of diverse topologies show that our method can reduce instance size at multiple levels with virtually no losses in solution quality on the latest D-wave quantum annealers.
Hard combinatorial optimization problems, often mapped to Ising models, promise potential solutions with quantum advantage but are constrained by limited qubit counts in near-term devices. We present an innovative quantum-inspired framework that dynamically compresses large Ising models to fit available quantum hardware of different sizes. Thus, we aim to bridge the gap between large-scale optimization and current hardware capabilities. Our method leverages a physics-inspired GNN architecture to capture complex interactions in Ising models and accurately predict alignments among neighboring spins (aka qubits) at ground states. By progressively merging such aligned spins, we can reduce the model size while preserving the underlying optimization structure. It also provides a natural trade-off between the solution quality and size reduction, meeting different hardware constraints of quantum computing devices. Extensive numerical studies on Ising instances of diverse topologies show that our method can reduce instance size at multiple levels with virtually no losses in solution quality on the latest D-wave quantum annealers.
Hard combinatorial optimization problems, often mapped to Ising models, promise potential solutions with quantum advantage but are constrained by limited qubit counts in near-term devices. We present an innovative quantum-inspired framework that dynamically compresses large Ising models to fit available quantum hardware of different sizes. Thus, we aim to bridge the gap between large-scale optimization and current hardware capabilities. Our method leverages a physics-inspired GNN architecture to capture complex interactions in Ising models and accurately predict alignments among neighboring spins (aka qubits) at ground states. By progressively merging such aligned spins, we can reduce the model size while preserving the underlying optimization structure. It also provides a natural trade-off between the solution quality and size reduction, meeting different hardware constraints of quantum computing devices. Extensive numerical studies on Ising instances of diverse topologies show that our method can reduce instance size at multiple levels with virtually no losses in solution quality on the latest D-Wave quantum annealers. Additionally, we demonstrate that GNN architectures can address the parameter initialization challenge in variational quantum algorithms, specifically QAOA for MaxCut problems, by learning structure-to-parameter mappings that achieve performance comparable with physics-based heuristics when trained on sufficiently large datasets.
Quantum computing has emerged as a promising computational paradigm with the potential to solve problems that are intractable for classical computers. This paper provides an overview of the current state of quantum computing, including its historical development, hardware advancements, applications, and challenges. Special attention is given to combinatorial optimization, which is considered one of the most promising application domains. The limitations of current quantum systems and future research directions are also discussed. This paper presents a comparative study between a conventional D-Wave-based simulated annealing approach and a proposed hybrid optimization model for solving largescale combinatorial optimization problems. The study focuses on benchmark problems, including AES, TSP gr24, and a real-world load balancing problem, all formulated as QUBO models. The D-Wave approach employs the dwave-neal simulated annealing engine with various parameter settings, while the proposed model introduces a decomposition-based framework combined with adaptive parameter control and iterative refinement. The experimental results demonstrate that the proposed model consistently outperforms the conventional approach in terms of solution quality, achieving significantly lower energy values across all problem instances. In particular, for the TSP gr24 problem, the proposed model achieves near-optimal solutions with substantially reduced computation time. For large-scale problems such as AES and load balancing, the proposed model maintains scalability and robustness, whereas the conventional approach suffers from increased computational cost and performance degradation. Although the proposed method introduces additional computational steps, its hybrid structure effectively mitigates limitations related to local minima, parameter sensitivity, and scalability. These findings indicate that integrating classical optimization techniques with quantum-inspired methods is essential for practical applications. The proposed model provides a promising framework for solving complex real-world optimization problems and highlights the importance of hybrid approaches in advancing quantum annealing technologies.
Quantum Optimization (QO) is emerging as a promising approach to tackle hard combinatorial optimization problems by leveraging the unique computational properties of quantum hardware. In recent years, QO has gained traction in Machine Learning (ML), where problems such as clustering and vector quantization can be naturally expressed as Quadratic Unconstrained Binary Optimization (QUBO) problems. These ML applications often involve complex, high-dimensional data, which directly influences both the structure and scale of the resulting QUBO formulations. However, current quantum devices fall under the category of Noisy Intermediate-Scale Quantum (NISQ) hardware, which imposes significant limitations on qubit counts and small error rates. This dissertation investigates the impact of data complexity and data scale—as encountered in ML settings—on the effectiveness and feasibility of QO on NISQ devices. We propose novel, hardware-aware methods to overcome these challenges. The first part of this thesis focuses on the effect of data complexity for QO. We analyze how problem structure—particularly when QUBO formulations are derived from ML tasks—affects quantum solvability. We identify the spectral gap as a key factor in the success of adiabatic quantum algorithms and provide a theoretical and empirical analysis linking data-induced complexity to optimization performance.To address noise sensitivity and limited precision, we introduce a preprocessing framework based on a principled Branch-and-Bound algorithm that reduces dynamic range while preserving global optima. This improves robustness on both quantum annealers and classical solvers. In the second part, the thesis addresses challenges introduced by data scale. First, we propose a recursive Divide-and-Conquer strategy that breaks down large QUBO problems into tractable subproblems, demonstrated through an application to Bundle Adjustment in 3D scene reconstruction. Second, we introduce a variable and constraint generation method inspired by column generation for Integer Linear Programming, enabling dynamic QUBO size growth. This technique is successfully applied to Multi-Agent Pathfinding, where it scales well on NISQ devices while maintaining compatibility with classical solvers. Finally, we explore QUBO reformulations that reduce problem size through compact encodings and cyclic expansion, enabling the use of quantum hardware for tasks such as FPGA placement in chip design. Across all contributions, the developed algorithms are evaluated both theoretically and empirically, with experiments conducted on real quantum and quantum-inspired hardware. These methods significantly improve solution quality, scalability, and hardware compatibility, paving the way for more effective use of QO in practical settings. While tailored for NISQ era constraints, the results remain relevant for fault-tolerant quantum computing, offering insights into the long-term viability of QO across hardware generations.
The Ising machine, as a quantum-inspired computing system, can be used to efficiently solve combinatorial optimization problems. Ongoing studies have positioned it to potentially surpass the performance limitations of traditional computers. However, such Ising machines also suffer from scalability as the solution quality becomes sub-optimal when the problem size increases. In this work, we propose an Ising-based framework that uses a distributed Ising algorithm to find the near-optimal solution for large-scale Max-Cut problems through parallel processing via graph segmentation and reassembly. We selected the coherent Ising machine as the hardware solver and successfully found the solution for a 2000-node instance utilizing 20 computational bits on the Gset standard dataset. Additionally, we investigated the key factors influencing the system's performance and discovered that setting the number of reorganizations to one results in higher accuracy. Building on this configuration, we utilized a 100-bit CIM hardware platform (CPQC-1) to solve instances with varying numbers of nodes. The experimental results agree well with the theoretical simulations, confirming the practical feasibility of our method. Moreover, compared to existing Ising-based solvers, our algorithm significantly reduces computational resource requirements while achieving superior performance on large-scale combinatorial optimization problems, highlighting its effectiveness on quantum-inspired hardware.
Quantum computing promises to have a tremendous advantage over its classical counterpart for solving computationally hard problems, yet remains in a relatively early stage for practical applications owing to the limited capabilities of today’s quantum computers. The approach to the special purposes of quantum computers by exploiting the special-purpose physics-inspired or quantum-inspired computers is emerging as a novel alternative to its quantum counterpart in tackling hard problems in high-performance computing. Inspired by physics, the Ising machine — a type of special-purpose computer that implements or emulates physics or quantum effects of the Ising model to speed up finding solutions to optimization problems — has recently become an active research area in the field of combinatorial optimization. This paper is to address the key enabling software and hardware technology underlying physics-inspired optimization using Ising machines in the unified quadratic unconstrained binary optimization (QUBO) framework for modeling and solving computationally hard combinatorial optimization problems, and with an aim to shed some light on the challenges and opportunities associated with the ever-growing landscape of this novel high-performance computing.
Large-scale combinatorial scheduling problems -- job-shop scheduling, flow-shop scheduling, and vehicle routing among them -- remain NP-hard at practically relevant scale, and quantum computing has entered this space along two related tracks: genuinely quantum solvers, principally quantum annealers and gate-based devices running the quantum approximate optimization algorithm (QAOA), and quantum-inspired classical solvers, such as coherent Ising machines and digital annealers, that borrow the same Ising/QUBO problem structure without requiring quantum hardware. This article synthesizes both tracks as applied specifically to scheduling. We trace the theoretical foundations from quantum and simulated annealing through the QUBO formulation techniques that make scheduling problems solver-ready, then review direct applications to job-shop, flow-shop, and vehicle-routing problems, reporting the concrete, verified numbers the underlying studies provide. The consistent finding is that quantum hardware remains constrained by qubit connectivity, embedding overhead, and shallow achievable circuit depth to small benchmark instances, while quantum-inspired classical solvers, unconstrained by qubit count, already reach scheduling-relevant problem sizes with reported performance competitive with or exceeding classical heuristics. We close by identifying benchmarking rigor, hardware connectivity, and the near-total absence of work on dynamic, online scheduling as the field's clearest open problems.