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arXiv:2408.03376 · Nature Communications

Entanglement-enhanced learning of quantum processes at scale

Alireza Seif, Senrui Chen, Swarnadeep Majumder, Haoran Liao, Derek S. Wang, Moein Malekakhlagh, Ali Javadi-Abhari, Liang Jiang, Zlatko Minev

Published Jul 23, 2026• 1 citation
arXivHTMLPDF

Abstract

Learning unknown noise processes in quantum systems reveals their physical origin and informs error suppression, mitigation, and correction. Characterizing a general quantum process requires exponentially many parameters inferred from noncommuting measurements. Because these measurements cannot be performed simultaneously, the sample complexity grows exponentially. For Pauli channels, quantum memory and entangling operations can transform this task into measurements of commuting observables, reducing complexity exponentially. However, noise in these resources increases the overhead, leaving open whether any advantage remains in realistic devices. Here, we introduce error-mitigated entanglement-enhanced learning, analyze it theoretically, and demonstrate it experimentally. We quantify the noise-induced overhead, perform hypothesis testing with up to 64 qubits, and learn intrinsic noise in parallel-gate layers using up to 16 qubits of a superconducting processor. We show that noisy quantum memory provides a learning advantage, with a current experimental overhead of 1.33 ± 0.05 per qubit, below the no-entanglement lower bound of 2. The authors show that entanglement with noisy quantum memory can significantly speed up learning of quantum processes. With error mitigation, their method characterizes quantum noise at scale and outperforms entanglement-free approaches.

DOI
10.1038/s41467-026-75553-0

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Learning unknown noise processes in quantum systems reveals their physical origin and informs error suppression, mitigation, and correction. Characterizing a general quantum process requires exponentially many parameters inferred from noncommuting measurements. Because these measurements cannot be performed simultaneously, the sample complexity grows exponentially. For Pauli channels, quantum memory and entangling operations can transform this task into measurements of commuting observables, reducing complexity exponentially. However, noise in these resources increases the overhead, leaving open whether any advantage remains in realistic devices. Here, we introduce error-mitigated entanglement-enhanced learning, analyze it theoretically, and demonstrate it experimentally. We quantify the noise-induced overhead, perform hypothesis testing with up to 64 qubits, and learn intrinsic noise in parallel-gate layers using up to 16 qubits of a superconducting processor. We show that noisy quantum memory provides a learning advantage, with a current experimental overhead of 1.33 ± 0.05 per qubit, below the no-entanglement lower bound of 2. The authors show that entanglement with noisy quantum memory can significantly speed up learning of quantum processes. With error mitigation, their method characterizes quantum noise at scale and outperforms entanglement-free approaches.
We develop a framework for learning from noisy quantum experiments in which fault-tolerant devices access uncharacterized systems through noisy couplings. Introducing the complexity class NBQP\textsf{NBQP}NBQP ("noisy BQP''), we model noisy fault-tolerant quantum computers that cannot generally error-correct the oracle systems they query. Using this class, we prove that while noise can eliminate the exponential quantum learning advantages of unphysical, noiseless learners, a superpolynomial gap remains between NISQ\textsf{NISQ}NISQ and fault-tolerant devices. Turning to canonical learning tasks in noisy settings, we find that the exponential two-copy advantage for purity testing collapses under local depolarizing noise. Nevertheless, we identify a setting motivated by AdS/CFT in which noise-resilient physical structure restores this quantum learning advantage. We then analyze noisy Pauli shadow tomography, deriving lower bounds characterizing how instance size, quantum memory and noise jointly control sample complexity, and design algorithms with parametrically matching scalings. We study similar tradeoffs in quantum metrology, and show that the Heisenberg-limited sensitivity of existing error-correction-based protocols persists only up to a timescale inverse-polynomial in the error rate per probe qubit. Together, our results demonstrate that the primitives underlying quantum-enhanced experiments are fundamentally fragile to noise, and that realizing meaningful quantum advantages in future experiments will require interfacing noise-robust physical properties with available algorithmic techniques.
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Quantum computers may reveal features of Nature inaccessible to conventional experiments, but manipulating raw quantum data introduces noise that degrades inference even when the processor is fault-tolerant, creating a data-input bottleneck for robust quantum learning. Here we show that quantum fault tolerance can substantially improve the sample complexity of learning from noisy experiments. We encode unknown quantum states from physical experiments into protected quantum memory, enabling fault-tolerant implementations of quantum learning algorithms otherwise degraded by errors. Using this quantum uploading procedure, we prove that noisy randomized measurement and multi-copy learning tasks can be performed exponentially faster than by any adaptive strategy that does not immediately encode physical states into error-corrected memory. These separations are not simply due to a reduced effective noise rate: they hold even when uploading is substantially noisier than the bare experimental interface, rigorously establishing immediate encoding as the optimal approach to noise-robust learning. We numerically illustrate the speedups in astronomical imaging, where quantum processing of uploaded photons locates an exoplanet obscured by a bright star using orders of magnitude fewer shots than unencoded baselines. Our results establish a robust interface between quantum computers and natural systems, enabling powerful and practical quantum-enhanced experiments.
Quantum computing holds unparalleled potentials to enhance machine learning. However, a demonstration of quantum learning advantage has not been achieved so far. We make a step forward by rigorously establishing a noise-robust, unconditional quantum learning advantage in expressivity, inference speed, and training efficiency, compared to commonly-used classical models. Our proof is information-theoretic and pinpoints the origin of this advantage: entanglement can be used to reduce the communication required by non-local tasks. In particular, we design a task that can be solved with certainty by quantum models with a constant number of parameters using entanglement, whereas commonly-used classical models must scale linearly to achieve a larger-than-exponentially-small accuracy. We show that the quantum model is trainable with constant resources and robust against constant noise. Through numerical and trapped-ion experiments on IonQ Aria, we demonstrate the desired advantage. Our results provide valuable guidance for demonstrating quantum learning advantages with current noisy intermediate-scale devices.
Understanding what can be learned from experiments is central to scientific progress. In this work, we use a learning-theoretic perspective to study the task of learning physical operations in a quantum machine when all operations (state preparation, dynamics, and measurement) are a priori unknown. We prove that, without any prior knowledge, if one can explore the full quantum state space by composing the operations, then every operation can be learned. When one cannot explore the full state space but all operations are approximately known and noise in Clifford gates is gate-independent, we find an efficient algorithm for learning all operations up to a single unlearnable parameter characterizing the fidelity of the initial state. For learning a noise channel on Clifford gates to a fixed accuracy, our algorithm uses quadratically fewer experiments than previously known protocols. Under more general conditions, the true description of the noise can be unlearnable; for example, we prove that no benchmarking protocol can learn gate-dependent Pauli noise on Clifford+T gates even under perfect state preparation and measurement. Despite not being able to learn the noise, we show that a noisy quantum computer that performs entangled measurements on multiple copies of an unknown state can yield a large advantage in learning properties of the state compared to a noiseless device that measures individual copies and then processes the measurement data using a classical computer. Concretely, we prove that noisy quantum computers with two-qubit gate error rate εεε can achieve a learning task using NNN copies of the state, while NΩ(1/ε)N^{Ω(1/ε)}NΩ(1/ε) copies are required classically.