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arXiv:2406.13196 · Machine Learning Science and Technology

Quantum generative learning for high-resolution medical image generation

Amena Khatun, Kübra Yeter Aydeniz, Yaakov S. Weinstein, Muhammad Usman

Published Apr 28, 2025• 19 citations
arXivHTMLPDF

Abstract

Abstract Integration of quantum computing in generative machine learning models has the potential to offer benefits such as training speed-up and superior feature extraction. However, the existing quantum generative adversarial networks (QGANs) fail to generate high-quality images due to their patch-based, pixel-wise learning approaches. These methods capture only local details, ignoring the global structure and semantic information of images. In this work, we address these challenges by proposing a quantum image generative learning (QIGL) approach for high-quality medical image generation. Our proposed quantum generator leverages variational quantum circuit approach addressing scalability issues by extracting principal components from the images instead of dividing them into patches. Additionally, we integrate the Wasserstein distance within the QIGL framework to generate a diverse set of medical samples. Through a systematic set of simulations on x-ray images from knee osteoarthritis and medical MNIST datasets, our model demonstrates superior performance, achieving the lowest Fréchet inception distance scores compared to its classical counterpart and advanced QGAN models reported in the literature.

DOI
10.1088/2632-2153/add1a9

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Quantum generative adversarial networks (QGANs) have attracted increasing attention for their potential to surpass classical generative models by leveraging the expressive power of parameterized quantum circuits (PQCs). However, in the current noisy intermediate-scale quantum era, the implementation of fully quantum algorithms is hindered by hardware limitations, restricting most existing approaches to low-resolution generated image. To address this challenge, we propose a hybrid quantum-classical generative adversarial network for patch-based image generation. Our method employs dual PQC-based generators that decompose images into structured patches, while local and global classical discriminators jointly capture local details and preserve global structural coherence. This design addresses scalability limitations of existing QGANs and mitigates patch-boundary artifacts, thereby enabling high-resolution image generation on hardware with restricted qubit counts. Experimental results validate the effectiveness of the proposed method, demonstrating improvements in image fidelity over existing baselines, and providing insights into the influence of qubit count on generative performance.
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