Challenges
Datasets
Workspaces
Papers
Discussions
Leaderboard
Log inSign up
Challenges
Datasets
Workspaces
Papers
Discussions
Leaderboard
Blog
Job Board
Q3AS

© 2026 Aqora Quantum S.A.S.

TermsPrivacyLegal Notice

arXiv:2401.15804

Brain Tumor Diagnosis Using Quantum Convolutional Neural Networks

Muhammad Al-Zafar Khan, Abdullah Al Omar Galib, Nouhaila Innan, Mohamed Bennai

Published Jan 28, 2024• 8 citations
arXivHTMLPDF

Abstract

Accurate classification of brain tumors from MRI scans is critical for effective treatment planning. This study presents a Hybrid Quantum Convolutional Neural Network (HQCNN) that integrates quantum feature-encoding circuits with depth-wise separable convolutional layers to analyze images from a publicly available brain tumor dataset. Evaluated on this dataset, the HQCNN achieved 99.16% training accuracy and 91.47% validation accuracy, demonstrating robust performance across varied imaging conditions. The quantum layers capture complex, non-linear relationships, while separable convolutions ensure computational efficiency. By reducing both parameter count and circuit depth, the architecture is compatible with near-term quantum hardware and resource-constrained clinical environments. These results establish a foundation for integrating quantum-enhanced models into medical-imaging workflows with minimal changes to existing software platforms. Future work will extend evaluation to multi-center cohorts, assess real-time inference on quantum simulators and hardware, and explore integration with surgical-planning systems.

DOI
10.48550/arxiv.2401.15804

Related papers

A Hybrid Quantum-Classical Deep Learning Framework for Efficient Brain Tumor Classification Using MRI Images

Sayali Nale, Tejashree Jena, Anita Atiwadkar

Accurate and computationally efficient classification of brain tumors from MRI scans is critical for deployment in resource-constrained clinical settings, where conventional deep CNN architectures-despite achieving strong accuracy-often require large parameter counts that limit scalability. This work proposes a hybrid quantum-classical deep learning framework that combines a classical convolutional feature extractor with a variational quantum circuit (VQC) for multi-class tumor classification. Spatial features extracted by the CNN backbone will be dimensionality-reduced and encoded into quantum states using angle encoding; a parameterized quantum circuit will then process these features in a higher-dimensional Hilbert space, leveraging superposition and entanglement to capture non-linear feature correlations. Measurement outputs from the quantum layer will be passed to a classical fully connected layer for classification into glioma, meningioma, pituitary tumor, and no-tumor categories. The proposed framework will be evaluated on a publicly available benchmark MRI dataset and benchmarked against state-of-the-art classical CNN architectures in terms of accuracy, precision, recall, F1-score, and parameter efficiency. This study aims to demonstrate that quantum-enhanced layers can achieve competitive classification performance while substantially reducing trainable parameters, offering a practical direction for efficient, quantum-assisted medical image analysis.

International Journal of Innovative Research in Technology•Sep 15, 2026•0 citations

Application of Quantum Convolutional Neural Networks for MRI-Based Brain Tumor Detection and Classification

Sugih Pratama Nugraha, Ariiq Islam Alfajri, Tony Ibnu Sumaryada +4 more

This study explores the application of Quantum Convolutional Neural Networks (QCNNs) for brain tumor classification using MRI images, leveraging quantum computing for enhanced computational efficiency. A dataset of 3,264 MRI images, including glioma, meningioma, pituitary tumors, and non-tumor cases, was utilized. The data was split into 80% training and 20% testing, with an oversampling technique applied to address class imbalance. The QCNN model consists of quantum convolution layers, flatten layers, and dense layers, with a filter size of 2, depth of 4, and 4 qubits, trained over 10 epochs. Two models were developed: a binary classification model distinguishing tumor presence and a multiclass classification model categorizing tumor types. The binary model achieved 88% accuracy, improving to 89% after data balancing, while the multiclass model achieved 52% accuracy, increasing to 62% after oversampling. Despite strong binary classification performance, the multiclass model faced challenges due to dataset complexity and quantum circuit limitations. These findings suggest that QCNNs hold promise for medical imaging applications, particularly in binary classification. However, further refinements, including optimized quantum circuit architectures and hybrid classical-quantum approaches, are necessary to enhance multiclass classification accuracy and improve QCNN applicability in clinical settings.

arXiv:2509.02582•Aug 28, 2025•0 citations

MRI Brain Tumor Detection using Hybrid Quantum and Classical Neural Networks

Ragavamsi Davuluri, Chitturi Jayasree, Abdul Naasir Ahamad +2 more

Brain tumor detection from MRI images is a critical and challenging task in medical diagnostics, where early identification greatly improves treatment outcomes. This paper presents a Hybrid Quantum– Classical Convolutional Neural Network (HQCNN) that integrates the strengths of ResNet-18 and a Variational Quantum Circuit for efficient and accurate tumor classification. The proposed model first employs ResNet-18 as a classical feature extractor, where 17 convolutional layers and pooling operations capture both low-level and high-level spatial features from MRI images. The final fully connected layer of ResNet-18 is replaced by a quantum processing layer implemented using PennyLane. In this layer, the extracted classical features are encoded onto qubits using RY rotation gates, while CNOT gates introduce entanglement between them, forming a VQC with trainable parameters. After quantum computation, Pauli-Z measurements convert the processed quantum states back into classical values, which are passed to a final fully connected layer for binary classification as Tumor or No Tumor. The hybrid integration of classical CNN feature learning with quantum entanglement– based representation enhances model generalization and interpretability. Experimental analysis demonstrates that the proposed HQCNN achieved 94.65% accuracy, outperforming traditional CNN models and confirming the potential of hybrid quantum–classical architectures for reliable and interpretable medical image diagnosis.

International Conference on Image Processing and Capsule Networks (ICIPCN)•Jan 27, 2026•1 citation

Brain Tumour Detection Using Quantum Convolutional Neural Networks (QCNN)

Sivaraju Venkata Sai Karthik, K Snehanvitha, Addanki Sai Kumar +3 more

Brain tumor detection is a vital and challenging task in medical diagnosis, requiring highly precise and efficient methods to improve patient treatment outcomes. Traditional approaches rely on classical machine learning and deep learning techniques, which, while effective to a degree, often struggle with capturing the complex and high-dimensional patterns present in medical imaging data. A significant limitation of these conventional methods is their inability to process and analyze intricate features efficiently, which can impact diagnostic accuracy. To address these challenges, this work proposes a novel Quantum Convolutional Neural Network (QCNN) framework that combines quantum computing principles, via quantum circuits, with classical machine learning architectures implemented through tools like PyTorch and PennyLane. This hybrid approach enhances feature extraction and classification capabilities, leading to superior performance. Experimental results demonstrate that the QCNN model achieves an improved accuracy of 90 percent on the test dataset, surpassing traditional methods and showing promise for advancing brain tumor detection technology. This improvement is supported by consistent decreases in training and validation loss during model training, highlighting the robustness and efficacy of the quantum-enhanced model.

OITS International Conference on Information Technology (OCIT)•Dec 18, 2025•1 citation

Brain Tumor Detection Using Quantum Convolution Neural Networks

Karvi Pranay Kumar, Aryan Mahawar, Kunal Pratap Singh +3 more

Brain Tumor detection knows as tedious job poses huge intricacies. Though MRI(Magnetic Resonance Imaging) has made the life of clinicians easier by providing detailed cross-sections of the brain, thus making it easy to detect abnormalities, it is still very difficult to accurately categorize the different types of Brain Tumors. For addressing this problem, this research work proposes a novel approach to use a Hybrid Quantum Classical Convolutional Neural Network (HQC-CNN) model. The proposed model has been experimented on the BraTS2023 dataset, with a result of 98.7% accuracy, which is an improvement of 5.2% over traditional CNNs (ResNet, VGG). The HQC-CNN model simplifies parameter complexity by 40% and training time by 2.5 times via quantum parallelism. The complete flow is described in the architecture, hybrid training regimes, and issues in deploying QCNNs on near-term quantum hardware in this work. These findings strongly indicates the power of Deep Learning approaches and incorporation of Quantum ideas in medical imaging.

International Conference on Intelligent Systems for Communication, IoT and Security (ICISCoIS)•Jan 8, 2026•1 citation

Hybrid Quantum-Classical Convolutional Neural Networks with Gradient Variance-Controlled Optimization for Medical Images Classification

Mohammed Yousif, Mohammad Amjad Kamal

Medical image classification poses significant challenges due to the complex and nonlinear patterns present in imaging data. Traditional deep learning models often struggle to capture the intricate relationships inherent in such data, especially under conditions of noise and training instability. To address these limitations, this study proposes a novel Hybrid Quantum Convolutional Neural Network (HQCNN) integrated with a Gradient Variance-Controlled Optimizer (GVCO). The aim is to enhance diagnostic accuracy by combining classical convolutional layers for shallow feature extraction with a parameterized quantum circuit (PQC) that enables richer and more discriminative feature representations. The GVCO dynamically adjusts learning rates and momentum coefficients based on real-time gradient variance, improving convergence speed and generalization performance. The proposed HQCNN-GVCO model was evaluated on two public brain imaging datasets: the Kaggle Brain MRI dataset and the REMBRANDT dataset. It achieved classification accuracies of 99.2% and 98.2%, respectively. Compared to baseline HQCNN and other state-of-the-art models, HQCNN-GVCO demonstrated superior and more consistent performance. These findings highlight the potential of integrating quantum computing techniques with adaptive optimization strategies to advance reliable and accurate medical image analysis.

Journal of Artificial Intelligence in Medical Applications•Sep 16, 2025•1 citation
Accurate classification of brain tumors from MRI scans is critical for effective treatment planning. This study presents a Hybrid Quantum Convolutional Neural Network (HQCNN) that integrates quantum feature-encoding circuits with depth-wise separable convolutional layers to analyze images from a publicly available brain tumor dataset. Evaluated on this dataset, the HQCNN achieved 99.16% training accuracy and 91.47% validation accuracy, demonstrating robust performance across varied imaging conditions. The quantum layers capture complex, non-linear relationships, while separable convolutions ensure computational efficiency. By reducing both parameter count and circuit depth, the architecture is compatible with near-term quantum hardware and resource-constrained clinical environments. These results establish a foundation for integrating quantum-enhanced models into medical-imaging workflows with minimal changes to existing software platforms. Future work will extend evaluation to multi-center cohorts, assess real-time inference on quantum simulators and hardware, and explore integration with surgical-planning systems.
Accurate and computationally efficient classification of brain tumors from MRI scans is critical for deployment in resource-constrained clinical settings, where conventional deep CNN architectures-despite achieving strong accuracy-often require large parameter counts that limit scalability. This work proposes a hybrid quantum-classical deep learning framework that combines a classical convolutional feature extractor with a variational quantum circuit (VQC) for multi-class tumor classification. Spatial features extracted by the CNN backbone will be dimensionality-reduced and encoded into quantum states using angle encoding; a parameterized quantum circuit will then process these features in a higher-dimensional Hilbert space, leveraging superposition and entanglement to capture non-linear feature correlations. Measurement outputs from the quantum layer will be passed to a classical fully connected layer for classification into glioma, meningioma, pituitary tumor, and no-tumor categories. The proposed framework will be evaluated on a publicly available benchmark MRI dataset and benchmarked against state-of-the-art classical CNN architectures in terms of accuracy, precision, recall, F1-score, and parameter efficiency. This study aims to demonstrate that quantum-enhanced layers can achieve competitive classification performance while substantially reducing trainable parameters, offering a practical direction for efficient, quantum-assisted medical image analysis.
This study explores the application of Quantum Convolutional Neural Networks (QCNNs) for brain tumor classification using MRI images, leveraging quantum computing for enhanced computational efficiency. A dataset of 3,264 MRI images, including glioma, meningioma, pituitary tumors, and non-tumor cases, was utilized. The data was split into 80% training and 20% testing, with an oversampling technique applied to address class imbalance. The QCNN model consists of quantum convolution layers, flatten layers, and dense layers, with a filter size of 2, depth of 4, and 4 qubits, trained over 10 epochs. Two models were developed: a binary classification model distinguishing tumor presence and a multiclass classification model categorizing tumor types. The binary model achieved 88% accuracy, improving to 89% after data balancing, while the multiclass model achieved 52% accuracy, increasing to 62% after oversampling. Despite strong binary classification performance, the multiclass model faced challenges due to dataset complexity and quantum circuit limitations. These findings suggest that QCNNs hold promise for medical imaging applications, particularly in binary classification. However, further refinements, including optimized quantum circuit architectures and hybrid classical-quantum approaches, are necessary to enhance multiclass classification accuracy and improve QCNN applicability in clinical settings.
Brain tumor detection from MRI images is a critical and challenging task in medical diagnostics, where early identification greatly improves treatment outcomes. This paper presents a Hybrid Quantum– Classical Convolutional Neural Network (HQCNN) that integrates the strengths of ResNet-18 and a Variational Quantum Circuit for efficient and accurate tumor classification. The proposed model first employs ResNet-18 as a classical feature extractor, where 17 convolutional layers and pooling operations capture both low-level and high-level spatial features from MRI images. The final fully connected layer of ResNet-18 is replaced by a quantum processing layer implemented using PennyLane. In this layer, the extracted classical features are encoded onto qubits using RY rotation gates, while CNOT gates introduce entanglement between them, forming a VQC with trainable parameters. After quantum computation, Pauli-Z measurements convert the processed quantum states back into classical values, which are passed to a final fully connected layer for binary classification as Tumor or No Tumor. The hybrid integration of classical CNN feature learning with quantum entanglement– based representation enhances model generalization and interpretability. Experimental analysis demonstrates that the proposed HQCNN achieved 94.65% accuracy, outperforming traditional CNN models and confirming the potential of hybrid quantum–classical architectures for reliable and interpretable medical image diagnosis.
Brain tumor detection is a vital and challenging task in medical diagnosis, requiring highly precise and efficient methods to improve patient treatment outcomes. Traditional approaches rely on classical machine learning and deep learning techniques, which, while effective to a degree, often struggle with capturing the complex and high-dimensional patterns present in medical imaging data. A significant limitation of these conventional methods is their inability to process and analyze intricate features efficiently, which can impact diagnostic accuracy. To address these challenges, this work proposes a novel Quantum Convolutional Neural Network (QCNN) framework that combines quantum computing principles, via quantum circuits, with classical machine learning architectures implemented through tools like PyTorch and PennyLane. This hybrid approach enhances feature extraction and classification capabilities, leading to superior performance. Experimental results demonstrate that the QCNN model achieves an improved accuracy of 90 percent on the test dataset, surpassing traditional methods and showing promise for advancing brain tumor detection technology. This improvement is supported by consistent decreases in training and validation loss during model training, highlighting the robustness and efficacy of the quantum-enhanced model.
Brain Tumor detection knows as tedious job poses huge intricacies. Though MRI(Magnetic Resonance Imaging) has made the life of clinicians easier by providing detailed cross-sections of the brain, thus making it easy to detect abnormalities, it is still very difficult to accurately categorize the different types of Brain Tumors. For addressing this problem, this research work proposes a novel approach to use a Hybrid Quantum Classical Convolutional Neural Network (HQC-CNN) model. The proposed model has been experimented on the BraTS2023 dataset, with a result of 98.7% accuracy, which is an improvement of 5.2% over traditional CNNs (ResNet, VGG). The HQC-CNN model simplifies parameter complexity by 40% and training time by 2.5 times via quantum parallelism. The complete flow is described in the architecture, hybrid training regimes, and issues in deploying QCNNs on near-term quantum hardware in this work. These findings strongly indicates the power of Deep Learning approaches and incorporation of Quantum ideas in medical imaging.
Medical image classification poses significant challenges due to the complex and nonlinear patterns present in imaging data. Traditional deep learning models often struggle to capture the intricate relationships inherent in such data, especially under conditions of noise and training instability. To address these limitations, this study proposes a novel Hybrid Quantum Convolutional Neural Network (HQCNN) integrated with a Gradient Variance-Controlled Optimizer (GVCO). The aim is to enhance diagnostic accuracy by combining classical convolutional layers for shallow feature extraction with a parameterized quantum circuit (PQC) that enables richer and more discriminative feature representations. The GVCO dynamically adjusts learning rates and momentum coefficients based on real-time gradient variance, improving convergence speed and generalization performance. The proposed HQCNN-GVCO model was evaluated on two public brain imaging datasets: the Kaggle Brain MRI dataset and the REMBRANDT dataset. It achieved classification accuracies of 99.2% and 98.2%, respectively. Compared to baseline HQCNN and other state-of-the-art models, HQCNN-GVCO demonstrated superior and more consistent performance. These findings highlight the potential of integrating quantum computing techniques with adaptive optimization strategies to advance reliable and accurate medical image analysis.