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arXiv:2311.05680 · Physical Review Research

Real-time error mitigation for variational optimization on quantum hardware

Matteo Robbiati, Alejandro Sopena, Andrea Papaluca, Stefano Carrazza

Published Jan 12, 2026• 3 citations
arXivHTMLPDF

Abstract

In this work, we put forward the inclusion of error mitigation routines in the process of training variational quantum circuit (VQC) models. In detail, we define a real-time quantum error mitigation (RTQEM) algorithm to assist in fitting functions on quantum chips with VQCs. While state-of-the-art QEM methods cannot address the exponential loss concentration induced by noise in current devices, we demonstrate that our RTQEM routine can enhance VQCs’ trainability by reducing the corruption of the loss function. We tested the algorithm by simulating and deploying the fit of a monodimensional u -quark parton distribution function on a superconducting single-qubit device, and we further analyzed the scalability of the proposed technique by simulating a multidimensional fit with up to eight qubits.

DOI
10.1103/zyb2-zl2d

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In this work, we put forward the inclusion of error mitigation routines in the process of training variational quantum circuit (VQC) models. In detail, we define a real-time quantum error mitigation (RTQEM) algorithm to assist in fitting functions on quantum chips with VQCs. While state-of-the-art QEM methods cannot address the exponential loss concentration induced by noise in current devices, we demonstrate that our RTQEM routine can enhance VQCs’ trainability by reducing the corruption of the loss function. We tested the algorithm by simulating and deploying the fit of a monodimensional u -quark parton distribution function on a superconducting single-qubit device, and we further analyzed the scalability of the proposed technique by simulating a multidimensional fit with up to eight qubits.
Quantum noise poses a significant challenge for current near-term quantum computing. Quantum error mitigation (QEM) has therefore emerged as a key strategy, offering a practical and effective solution to reduce error impacts and enhance the performance of near-term variational quantum circuits (VQC). Given the lack of a comprehensive survey on this important topic in the literature, this article provides a dedicated overview of QEM, including both during and after the training of VQC. Specifically, during VQC training, we explore and discuss key QEM techniques such as optimal control and dynamical decoupling. For the post-processing stage of VQC, we will examine and discuss mitigation techniques such as zero-noise extrapolation (ZNE) and probabilistic error cancellation (PEC). For each of these QEM techniques, we will investigate the fundamentals, mitigation concepts, and recent advances. Subsequently, we also explore research toolboxes, including Mitiq and Qiskit Aer, as well as provide a case study that demonstrates contextual multi-armed bandit-guided ZNE. Finally, we discuss ongoing problems and future research initiatives, including ML-assisted mitigation and integration with error correction. This survey article aims to synthesize the state-of-the-art in QEM, offer organized insights across approaches, and propose potential paths towards error-resilient quantum computing.
Machine Learning-based quantum error mitigation (ML-QEM) has emerged as a promising approach for improving the performance of noisy quantum algorithms. However, existing ML-QEM methods often have restricted applicability to variational circuits and rely on inaccessible noiseless training data. In this work, we propose a practical ML-QEM protocol tailored to variational quantum algorithms, which generates training data by simulating (near-)Clifford circuits. This data is used for model selection and training, producing a mitigation model that can correct variational circuits with arbitrary parameters and transfer across different target Hamiltonians of similar structure. We benchmark the proposed method on the Variational Quantum Eigensolver (VQE) task for the Sherrington-Kirkpatrick Hamiltonian of up to n=12n=12n=12 qubits under various noise models, analyzing its effect on trainability and comparing its performance against standard Zero-Noise Extrapolation (ZNE). The results demonstrate consistent several-fold error suppression across all tested settings and superior performance over ZNE in the high-noise regime, providing evidence for the applicability of the proposed protocol to present-day NISQ processors.
Variational quantum circuits (VQCs) solving partial differential equations (PDEs) on near-term quantum hardware face a critical challenge: hardware noise degrades solution fidelity and disrupts convergence. We present a systematic study of three noise channels; depolarizing, amplitude damping, and bit-flip on VQCs constrained by PDE residual loss functions for the heat equation, Burgers' equation, and the Saint-Venant shallow water equations. We benchmark three error mitigation strategies: zero-noise extrapolation (ZNE) via Richardson polynomial fitting, probabilistic error cancellation (PEC), and measurement error mitigation through inverse confusion matrices. Our numerical experiments on 6-qubit, 4-layer circuits demonstrate that ZNE reduces absolute error by 82-96% at low noise (p = 0.001), with effectiveness degrading gracefully at higher noise strengths. We prove analytically and confirm numerically that physics-constrained circuits exhibit inherent noise resilience: at p = 0.01, constrained circuits maintain 25-47% higher fidelity than unconstrained counterparts, with the advantage scaling with PDE complexity. PEC provides near-exact correction at low gate counts but incurs exponential sampling overhead, rendering it impractical beyond ~60 gates at p >= 0.02. Error budget decomposition reveals that systematic errors dominate at all noise levels (43-58%), while the PDE residual component grows from ~10% to ~31% as noise increases, indicating that physics constraints absorb noise through structured gradient information. These results establish practical guidelines for deploying variational PDE solvers on NISQ hardware.
Quantum error mitigation techniques are at the heart of quantum hardware implementation, and are the key to performance improvement of the variational quantum learning scheme (VQLS). Although VQLS is partially robust to noise, both empirical and theoretical results exhibit that noise would rapidly deteriorate the performance of most variational quantum algorithms in large-scale problems. Furthermore, VQLS suffers from the barren plateau phenomenon---the gradient generated by the classical optimizer vanishes exponentially with respect to the qubit number. Here we devise a resource and runtime efficient scheme, the quantum architecture search scheme (QAS), to maximally improve the robustness and trainability of VQLS. In particular, given a learning task, QAS actively seeks an optimal circuit architecture to balance benefits and side-effects brought by adding more quantum gates. Specifically, while more quantum gates enable a stronger expressive power of the quantum model, they introduce a larger amount of noise and a more serious barren plateau scenario. Consequently, QAS can effectively suppress the influence of quantum noise and barren plateaus. We implement QAS on both the numerical simulator and real quantum hardware, via the IBM cloud, to accomplish data classification and quantum chemistry tasks. Numerical and experimental results show that QAS significantly outperforms conventional variational quantum algorithms with heuristic circuit architectures. Our work provides practical guidance for developing advanced learning-based quantum error mitigation techniques on near-term quantum devices.
Abstract We present a method to improve the convergence of variational algorithms based on hidden inverses (HIs) to mitigate coherent errors. In the context of error mitigation, this means replacing the hardware implementation of certain Hermitian gates with their inverses. Doing so results in noise cancellation and a more resilient quantum circuit. This approach improves performance in a variety of two-qubit error models where the noise operator also inverts with the gate inversion. We apply the mitigation scheme on superconducting quantum processors running the variational quantum eigensolver (VQE) algorithm to find the H 2 ground-state energy. When implemented on superconducting hardware we find that the mitigation scheme effectively reduces the energy fluctuations in the parameter learning path in VQE, reducing the number of iterations for a converged value. We also provide a detailed numerical simulation of VQE performance under different noise models and explore how HIs and randomized compiling affect the underlying loss landscape of the learning problem. These simulations help explain our experimental hardware outcomes, helping to connect lower-level gate performance to application-specific behavior in contrast to metrics like fidelity which often do not provide an intuitive insight into observed high level performance.
Variational Quantum Algorithms (VQAs) are often viewed as the best hope for near-term quantum advantage. However, recent studies have shown that noise can severely limit the trainability of VQAs, e.g., by exponentially flattening the cost landscape and suppressing the magnitudes of cost gradients. Error Mitigation (EM) shows promise in reducing the impact of noise on near-term devices. Thus, it is natural to ask whether EM can improve the trainability of VQAs. In this work, we first show that, for a broad class of EM strategies, exponential cost concentration cannot be resolved without committing exponential resources elsewhere. This class of strategies includes as special cases Zero Noise Extrapolation, Virtual Distillation, Probabilistic Error Cancellation, and Clifford Data Regression. Second, we perform analytical and numerical analysis of these EM protocols, and we find that some of them (e.g., Virtual Distillation) can make it harder to resolve cost function values compared to running no EM at all. As a positive result, we do find numerical evidence that Clifford Data Regression (CDR) can aid the training process in certain settings where cost concentration is not too severe. Our results show that care should be taken in applying EM protocols as they can either worsen or not improve trainability. On the other hand, our positive results for CDR highlight the possibility of engineering error mitigation methods to improve trainability.