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arXiv:2310.02748 · IEEE International Conference on Quantum Computing and Engineering (QCE)

Hybrid Quantum Machine Learning Assisted Classification of COVID-19 from Computed Tomography Scans

Leo Sünkel, Darya Martyniuk, Julia Reichwald, Andrei Morariu, Raja Havish Seggoju, Philipp J. Altmann, Christoph Roch, Adrian Paschke

Published Sep 17, 2023• 9 citations
arXivHTMLPDF

Abstract

Practical quantum computing (QC) is still in its in-fancy and problems considered are usually fairly small, especially in quantum machine learning when compared to its classical counterpart. Image processing applications in particular require models that are able to handle a large amount of features, and while classical approaches can easily tackle this, it is a major challenge and a cause for harsh restrictions in contemporary QC. In this paper, we apply a hybrid quantum machine learning approach to a practically relevant problem with real world-data. That is, we apply hybrid quantum transfer learning to an image processing task in the field of medical image processing. More specifically, we classify large CT-scans of the lung into COVID-19, CAP, or Normal. We discuss quantum image embedding as well as hybrid quantum machine learning and evaluate several approaches to quantum transfer learning with various quantum circuits and embedding techniques.

DOI
10.1109/qce57702.2023.00048

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Practical quantum computing (QC) is still in its in-fancy and problems considered are usually fairly small, especially in quantum machine learning when compared to its classical counterpart. Image processing applications in particular require models that are able to handle a large amount of features, and while classical approaches can easily tackle this, it is a major challenge and a cause for harsh restrictions in contemporary QC. In this paper, we apply a hybrid quantum machine learning approach to a practically relevant problem with real world-data. That is, we apply hybrid quantum transfer learning to an image processing task in the field of medical image processing. More specifically, we classify large CT-scans of the lung into COVID-19, CAP, or Normal. We discuss quantum image embedding as well as hybrid quantum machine learning and evaluate several approaches to quantum transfer learning with various quantum circuits and embedding techniques.
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Classifying the severity of medical images using the quantum-classical model with respect to the desperately required COVID-19 virus screening area. It is a pandemic concern that is having an impact on millions of people’s lives. The most frequent result that involves expert evaluation in COVID-19 Computed Tomography(CT) images of the lungs is ground glass turbidity. Quantum Machine Learning (QML), is one of the fields that quantum computing has the ability to explore. These days, with so much data available, machine learning might gain from increased speed, computational complexity in which it needs a lot of weights for better performance. In this paper, exploring a machine learning issue using a quantum technique and quantum-classical hybrid model use for severity classification that perform on different input images 28*28, 32*32 and 64*64 that’s run on simulator. The research laid out in this paper shows that the hybrid model succeeds over CNN in terms of low resolution image size and fewer trainable parameters. Quantum-Classical model categorizes the patient’s Computed Tomography images into three severity classes: moderate, severe and critical. The best hybrid model in this study uses a 32*32 image size with accuracy of 96.82% and 3075 trainable parameters , whereas the VGG-19 model uses a 64*64 image size with 262659 trainable parameters provide accuracy of 85.97%.
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Quantum Transfer Learning (QTL) recently gained popularity as a hybrid quantum-classical approach for image classification tasks by efficiently combining the feature extraction capabilities of large Convolutional Neural Networks with the potential benefits of Quantum Machine Learning (QML). Existing approaches, however, only utilize gate-based Variational Quantum Circuits for the quantum part of these procedures. In this work we present an approach to employ Quantum Annealing (QA) in QTL-based image classification. Specifically, we propose using annealing-based Quantum Boltzmann Machines as part of a hybrid quantum-classical pipeline to learn the classification of real-world, large-scale data such as medical images through supervised training. We demonstrate our approach by applying it to the three-class COVID-CT-MD dataset, a collection of lung Computed Tomography (CT) scan slices. Using Simulated Annealing as a stand-in for actual QA, we compare our method to classical transfer learning, using a neural network of the same order of magnitude, to display its improved classification performance. We find that our approach consistently outperforms its classical baseline in terms of test accuracy and AUC-ROC-Score and needs less training epochs to do this.
Quantum Machine Learning (QML) is an emerging, powerful paradigm at the intersection of quantum computing and artificial intelligence, with the potential to enhance medical image analysis. We compared their performance with classical counterparts, while critically examining the gap between theoretical quantum advantages and the practical constraints of current Noisy Intermediate-Scale Quantum (NISQ) implementations. This review explored the current landscape of QML-based methodologies applied to key medical imaging modalities - Magnetic Resonance Imaging (MRI), Computed Tomography (CT), X-rays, and histopathology. We systematically analyzed how quantum-enhanced models were employed for critical tasks such as image classification, segmentation, and reconstruction, and we compared their performance with that of classical counterparts. The review delved into the architectural innovations that enabled these quantum approaches, including hybrid quantum-classical frameworks, variational quantum circuits, and quantum convolutional neural networks. Particular emphasis was given to the clinical relevance of QML applications, from early diagnostics to real-time surgery planning, and how quantum advantage might influence data efficiency, interpretability, along computational scalability. Finally, we highlighted current challenges in data encoding, noise resilience, and hardware limitations, and discussed promising future directions that could enable the practical deployment of QML in healthcare settings. This comprehensive review aimed to serve as a foundational reference for researchers and practitioners looking to harness quantum computing in medical imaging and precision medicine.